Co-localization of plaque macrophages with calcification is associated with a more vulnerable plaque phenotype and a greater calcification burden in coronary target segments as determined by OCT
Fig 3
OCT image of a co-localization between macrophages and calcification.
Macrophage accumulation is highlighted with two white arrows, macrocalcification is contoured with a white dotted line. In the magnified section, the distance of 90μm (below the defined threshold for co-localization of 100μm) between macrophages and calcification is shown.