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Bile Acids Specifically Increase Hepatitis C Virus RNA-Replication

Figure 3

Influence of BAs on HCV particle production and infectivity.

Cells were transfected, seeded and treated as described in Fig. 2. Release of core protein as a measure of viral particles in the culture fluid was determined by a commercial core-specific ELISA (A). Infectivity of release particles was assessed by inoculation of naïve Lunet G-luc cells (B). Mean values of duplicates and the standard deviation are shown.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0036029.g003