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Herpes Virus Infection Is Associated with Vascular Remodeling and Pulmonary Hypertension in Idiopathic Pulmonary Fibrosis

Figure 3

Vascular remodelling in IPF lung tissue.

Significantly increased arterial thickening (A) particularly of the intimal layer (B) is seen in virus positive cases. Elastic Van Gieson stained sections showed increased wall thickening (increased elastic and collagen fibers) especially of the intimal layer (arrow) in virus positive (C) compared to virus negative cases (D). Bar scale: 100 µm. L = lumen.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0055715.g003