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Minimal Gene Regulatory Circuits for a Lysis-Lysogeny Choice in the Presence of Noise

Figure 4

Examples of two-protein+CII networks that can perform the decision task in the presence of noise.

In each network and are co-transcribed. The upper two networks (p.lyt.cII) work at the standard 6% noise level, while in the lower network CII production is shut off after the first replication (cII shut-off). This network functions at a 20% noise level. The left panels are as in Figure 3. The right panels show the time development of CII. All times are shown in units of the phage genome replication time, whereas CII levels are shown in units of its binding constant for activation of Lys protein production.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0015037.g004