The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses
Fig 5
Effect of SUMOylation pathway on AAV transduction is independent of MOI.
HeLa cells were transfected with different siRNAs and 48 h later transduced with ssAAV-firefly luciferase vectors at different MOIs as indicated. A: relative light units after 24 h incubation determined in three independent experiments, B: ratio of luciferase activity of cells treated with siRNA targeting Ubc9 and cells treated with ‘AllStars negative control siRNA’ (scrambled).