Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells
Figure 6
Tozasertib-induced apoptosis in UKF-NB-3 cells transduced with a lentiviral vector encoding shRNA directed against p53 (UKF-NB-3p53shRNA) and UKF-NB-3 transduced with a control vector expressing non-targeting scrambled shRNA (UKF-NB-3scr) as indicated by BAX activation, caspase 3/7 activation, and determination of sub-G1 cells.
* P<0.05 relative to UKF-NB-3scr.