Skip to main content

Advertisement

Log in

Repeated IL-10 measurement in aqueous humor and OCT imaging are valuable tools to monitor intraocular lymphoma treated with intravitreal injections of methotrexate

  • Case Report
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Nasir S, DeAngelis LM (2000) Update on the management of primary CNS lymphoma. Oncology (Williston Park) 14:228–234, discussion 237–242, 244

    CAS  Google Scholar 

  2. Whitcup SM, de Smet MD, Rubin BI, Palestine AG, Martin DF, Burnier M Jr, Chan CC, Nussenblatt RB (1993) Intraocular lymphoma. Clinical and histopathologic diagnosis. Ophthalmology 100:1399–1406

    PubMed  CAS  Google Scholar 

  3. Batchelor TT, Kolak G, Ciordia R, Foster CS, Henson JW (2003) High-dose methotrexate for intraocular lymphoma. Clin Cancer Res 9:711–715

    PubMed  CAS  Google Scholar 

  4. Velez G, Yuan P, Sung C, Tansey G, Reed GF, Chan CC, Nussenblatt RB, Robinson MR (2001) Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma. Arch Ophthalmol 119:1518–1524

    PubMed  CAS  Google Scholar 

  5. Frenkel S, Hendler K, Siegal T, Shalom E, Pe’er J (2008) Intravitreal methotrexate for treating vitreoretinal lymphoma: 10 years of experience. Br J Ophthalmol 92:383–388

    Article  PubMed  CAS  Google Scholar 

  6. Rajagopal R, Harbour JW (2011) Diagnostic testing and treatment choices in primary vitreoretinal lymphoma. Retina 31:435–440

    Article  PubMed  CAS  Google Scholar 

  7. de Smet MD, Vancs VS, Kohler D, Solomon D, Chan CC (1999) Intravitreal chemotherapy for the treatment of recurrent intraocular lymphoma. Br J Ophthalmol 83:448–451

    Article  PubMed  Google Scholar 

  8. Martin DF, Ficker LA, Aguilar HA, Gardner SK, Wilson LA, Meredith TA (1990) Vitreous cefazolin levels after intravenous injection. Effects of inflammation, repeated antibiotic doses, and surgery. Arch Ophthalmol 108:411–414

    Article  PubMed  CAS  Google Scholar 

  9. Voorzanger N, Touitou R, Garcia E, Delecluse HJ, Rousset F, Joab I, Favrot MC, Blay JY (1996) Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin’s lymphoma cells and act as cooperative growth factors. Cancer Res 56:5499–5505

    PubMed  CAS  Google Scholar 

  10. Cassoux N, Giron A, Bodaghi B, Tran TH, Baudet S, Davy F, Chan CC, Lehoang P, Merle-Beral H (2007) IL-10 measurement in aqueous humor for screening patients with suspicion of primary intraocular lymphoma. Invest Ophthalmol Vis Sci 48:3253–3259

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maher Saleh.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Saleh, M., Nikolitch, K., Bourcier, T. et al. Repeated IL-10 measurement in aqueous humor and OCT imaging are valuable tools to monitor intraocular lymphoma treated with intravitreal injections of methotrexate. Graefes Arch Clin Exp Ophthalmol 250, 761–764 (2012). https://doi.org/10.1007/s00417-011-1718-5

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-011-1718-5

Keywords

Navigation