Observations of Raman optical activity in the carbon–halogen stretching modes of both 1-chloro- and 1-bromo-2-methylbutanes demonstrate the unique sensitivity of this new chiroptical technique to the optical activity of individual conformers of the molecular skeleton.
M. Diem, M. J. Diem, B. A. Hudgens, J. L. Fry and D. F. Burow, J. Chem. Soc., Chem. Commun., 1976, 1028 DOI: 10.1039/C39760001028
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