1653862424     

491717539                        

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In silico toxicology : principles and applications / [edited by] Mark Cronin, Judith Madden

Cronin, Mark T. D. ; Madden, Judith

Cambridge : Royal Society of Chemistry, 2010 [Original: 2010]

Online-Ressource (581 p)

Englisch

9781849730044; i_iv; v_vi; vii_viii; ix_xviii; 001_010; 011_030; 031_058; 059_117; 118_147; 148_192; 193_209; 210_227; 228_251; 252_274; 275_300; 301_333; 334_345; 346_371; 372_384; 385_407; 408_445; 446_477; 478_507; 508_530; 531_557; 558_583; 584_605; 606_623; 624_644; 645_658; 659_670

Includes bibliographical references and index

Print version: In Silico Toxicology

1-84973-209-4 ; 978-1-84973-004-4 ; 978-1-84973-209-3

1849730040=9781849730044 (ISBN der Printausgabe)

741479559; 803186924

OCoLC: 642693514 (aus SWB)     

Digital Object Identifier (DOI): 10.1039/9781849732093

RA1235

547 ; 615.950113     Ähnliche Literatur

bisacsh: SCI 013040

LOC-SH: Organic compounds; Toxicity testing ; Animal Testing Alternatives; methods ; Computational Biology; methods ; Organic Chemicals; chemistry ; Organic Chemicals; toxicity ; Pharmaceutical Preparations; chemistry ; Toxicity Tests; methods ; Organic compounds -- Toxicity testing ; Organic compounds -- Toxicology -- Computer simulation

MeSH: Animal Testing Alternatives ; Computational Biology ; Organic Chemicals ; Organic Chemicals ; Pharmaceutical Preparations ; Toxicity Tests

In Silico methods to predict toxicity have become increasingly important recently, particularly in light of European legislation such as REACH and the Cosmetics Regulation. They are also being used extensively worldwide e.g. in the USA, Canada, Japan and Australia. In assessing the risk that a chemical may pose to human health or to the environment, focus is now being directed towards exploitation of in silico methods to replace in vivo or in vitro techniques. A prediction of potential toxicity requires several stages: 1) Collation and organisation of data available for the compound, or if thi