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  • Book
  • © 2011

Vaccines against Allergies

  • We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy.
  • In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients.
  • Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 352)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xi
  2. Immunological Approaches for Tolerance Induction in Allergy

    • Melanie L. Conrad, Harald Renz, Kurt Blaser
    Pages 1-26
  3. Clinical Experience with Recombinant Molecules for Allergy Vaccination

    • Oliver Cromwell, Verena Niederberger, Friedrich Horak, Helmut Fiebig
    Pages 27-42
  4. Allergen-Specific Immunotherapy with Recombinant Allergens

    • G. Pauli, Hans-Jørgen Malling
    Pages 43-54
  5. Vaccine Approaches for Food Allergy

    • Philip Rancitelli, Alison Hofmann, A. Wesley Burks
    Pages 55-69
  6. Intralymphatic Immunotherapy: From the Rationale to Human Applications

    • Gabriela Senti, Pål Johansen, Thomas M. Kündig
    Pages 71-84
  7. Induction of Allergen-Specific Tolerance via Mucosal Routes

    • Laurent Mascarell, Aline Zimmer, Laurence Van Overtvelt, Sophie Tourdot, Philippe Moingeon
    Pages 85-105
  8. T Cell Epitope-Based Allergy Vaccines

    • Mark Larché
    Pages 107-119
  9. Allergen-Specific Immunotherapy: Towards Combination Vaccines for Allergic and Infectious Diseases

    • Johanna Edlmayr, Katarzyna Niespodziana, Margarete Focke-Tejkl, Birgit Linhart, Rudolf Valenta
    Pages 121-140
  10. Passive Immunization with Allergen-Specific Antibodies

    • Sabine Flicker, Elisabeth Gadermaier, Christoph Madritsch, Rudolf Valenta
    Pages 141-159
  11. Cell-Based Therapy in Allergy

    • Ulrike Baranyi, Martina Gattringer, Rudolf Valenta, Thomas Wekerle
    Pages 161-179
  12. Back Matter

    Pages 181-182

About this book

We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients. Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects. In fact, more than 25% of the population suffer from IgE-mediated allergies which therefore represent a major health burden of our society, particularly because untreated allergy often progresses to severe disabling forms of disease, such as asthma and sometimes kills sensitized people through anaphylaxis.

Editors and Affiliations

  • Christian Doppler Laboratory for Allergy, Medical University of Vienna, Vienna, Austria

    Rudolf Valenta

  • Dynavax Technologies, Berkeley, USA

    Robert L. Coffman

Bibliographic Information

  • Book Title: Vaccines against Allergies

  • Editors: Rudolf Valenta, Robert L. Coffman

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-20054-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2011

  • Hardcover ISBN: 978-3-642-20053-3Published: 28 August 2011

  • Softcover ISBN: 978-3-642-27100-7Published: 25 November 2013

  • eBook ISBN: 978-3-642-20054-0Published: 26 August 2011

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XI, 182

  • Number of Illustrations: 20 b/w illustrations

  • Topics: Vaccine, Immunology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access