- AutorIn
- Manfred P. Wirth
- Michael Fröhner
- Titel
- Adjuvant Hormonal Treatment for Prostate Cancer: The Bicalutamide Early Prostate Cancer Program
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa-133551
- Quellenangabe
- Oncology 2003;65(suppl 1):1–4, ISSN: 0030-2414
- Erstveröffentlichung
- 2003
- Abstract (DE)
- Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
- Abstract (EN)
- Adjuvant hormonal therapy has been demonstrated to be able to delay disease progression in nonmetastatic prostate cancer. To date, however, a favorable impact on survival has only been demonstrated in lymph-node-positive disease and in external-beam radiotherapy series with locally advanced and probably mainly micrometastatic tumors. The Bicalutamide Early Prostate Cancer Program is the largest study under way to define the role of adjuvant treatment in early prostate cancer and identify subgroups of patients likely to benefit from immediate hormonal therapy. At the time of the most recently published analysis, the risk of objective clinical progression was significantly reduced in the bicalutamide arm (hazards ratio 0.58, 95% confidence interval 0.51–0.66, p < 0.0001). However, further maturation of data is needed to see whether this difference will lead to a survival advantage.
- Andere Ausgabe
- DOI: 10.1159/000072484
- Volltext des Artikels, der zuerst in der Zeitschrift "Oncology" des Karger-Verlages erschienen ist.
Link: http://dx.doi.org/10.1159/000072484 - Freie Schlagwörter (DE)
- Prostatakrebs, Prostatakarzinom, Hilfsstoff, Hormonbehandlung, Bicalutamid, radikale Prostatektomie, Strahlentherapie
- Freie Schlagwörter (EN)
- Prostate cancer, Adjuvant, Hormonal treatment, Bicalutamide, Radical prostatectomy, Radiotherapy, Watchful waiting
- Klassifikation (DDC)
- 610
- Klassifikation (RVK)
- XA 10000
- Verlag
- Karger, Basel
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa-133551
- Veröffentlichungsdatum Qucosa
- 12.02.2014
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis