CONTENTS; 1 Development of Endoscopic Devices:Past, Present and Future; 1.1 Introduction; 1.2 The Present; 1.3 The Future; References; 2 Surface Analysis with MagnifyingChromoendoscopy in the Colon; 2.1 Background; 2.2 Classification of Superficial Neoplastic ColorectalNeoplasia - a Consensus Workshop Approach; 2.3 Stereomicroscopy and 'Pit Patterns' in theHuman Colon; 2.4 Pit-pattern Classification and Magnification-Chromoscopic Appearances; 2.5 Magnification Chromoscopy in RoutineClinical Practice; 2.6 Current Endoluminal In Vivo Imaging Techniques; 2.6.1 Limitations and Data Summary 2.6.2 In Vivo Staging of Colorectal Lesions UsingMagnifying Chromoendoscopy2.6.3 Summary of Limitations of Current Technology; 2.7 Chromoscopic Colonoscopy and MagnifyingChromoendoscopy Imaging as an AdjunctiveScreening Tool in Colitis; 2.8 Clinical Recommendations and Conclusions; References; 3 Development and Current TechnologicalStatus of Confocal Laser Endomicroscopy; 3.1 Introduction; 3.2 Principles of Confocal Microscopy; 3.3 Miniaturisation - Fibre-Optic ConfocalMicroscopy; 3.4 Current Technology in the flexible GIendomicroscope 3.5 Current Technology - Key Features forEndomicroscopy of the GI Tract3.6 Summary and »Take-home« messages; References; 4 Examination Technique of Confocal LaserEndomicroscopy; 4.1 Introduction; 4.2 The Confocal Endomicroscope; 4.3 Patient Preparation; 4.4 In Vivo Confocal Imaging; 4.5 Fluorescent Agents; References; 5 The Technique of Confocal LaserEndomicroscopy from the Perspectiveof a New User; 5.1 Introduction; 5.2 Preparation for Endomicroscopic Imaging; 5.2.1 Entering Case Data and Imaging Sites; 5.2.2 Study the Control Screen; 5.2.3 Check the Laser and Calibrate 5.2.4 Obtaining Informed Consent5.3 General Technique of Confocal EndomicroscopicImaging; 5.3.1 Targeting of a Lesion or Area; 5.3.2 Achieving Contact of the Confocal Windowwith the Mucosa; 5.3.3 Acquiring a Stable Position; 5.3.4 Performing Endomicroscopic Imaging; 5.3.5 Planning the Anatomical Sites for EndomicroscopicImaging; 5.3.6 Identifying and Minimising Image Artefact; 5.3.7 Limitations; 5.4 Image Annotation, Export, Archive andReview; 5.4.1 Annotating Images; 5.4.2 Saving and Exporting Images; 5.4.3 Reviewing Images 6 Microarchitecture of the Normal GutSeen with Conventional Histology andEndomicroscopy6.1 Introduction; 6.2 General Structure and Components of theGastrointestinal Tract; 6.3 Mucosal Layer; 6.3.1 Oesophagus; 6.3.2 Endomicroscopic Imaging of NormalOesophageal Mucosa; 6.3.3 Stomach; 6.3.4 Endomicroscopic Imaging of Gastric Mucosa; 6.3.5 Small Bowel; 6.3.6 Endomicroscopic Imaging of Small BowelArchitecture; 6.3.7 Colon; 6.3.8 Endomicroscopic Imaging of Colonic Mucosa; 6.4 Lymphoid Tissue; 6.5 Innervation; 6.6 Endocrine Cells; 6.7 Vasculature; 6.8 Conclusion; References 7 Endomicroscopy of GI Disorders |