1753134641     

Diagnosis and Management of Hereditary Cancer : Tabular-Based Clinical and Genetic Aspects

San Diego : Elsevier Science & Technology, 2021 [©2021]

1 online resource (386 pages)

Englisch

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Erscheint auch als: (Druck-Ausgabe)

978-0-323-88582-9

978-0-323-90746-0 (ISBN der Printausgabe)

Elektronische Ressource: Zugang über Aggregator-Datenbank (Lizenzangabe: Lizenzpflichtig)

616.994042     Ähnliche Literatur

LOC-SH: Cancer -- Genetic aspects ; Cancer-Genetic aspects

Intro -- Diagnosis and Management of Hereditary Cancer: Tabular-Based Clinical and Genetic Aspects -- Copyright -- Dedications -- Contents -- Foreword -- Abbreviations -- Introduction -- Section A: Genetics -- Table 1. Concepts in hereditary cancer genetics -- Table 2. Genetic alterations in hereditary cancer -- Section B: Genetic testing -- Table 3. Genetic counseling considerations -- Table 4. Genetic testing-constitutional -- Table 5. Genetic testing-tumor -- Table 6. DNA sources for genetic testing -- Table 7. Variant annotation -- Table 8. Analysis of a detected alteration -- Table 9. ACMG evidence of pathogenicity -- Table 10. ACMG rules for variant classification -- Table 11. Oncogenes in hereditary cancers -- Table 12. Autosomal recessive hereditary cancers -- Table 13. Autosomal recessive, nonneoplastic hereditary conditions from cancer genes -- Table 14. Digenic modifiers, contiguous genes, and phenocopies -- Table 15. Mechanisms of phenotypic variability -- Table 16. Pseudogenes of cancer susceptibility genes -- Section C: Clinical features -- Table 17. Red flags suggesting hereditary cancer -- Table 18. Key issues in eliciting and evaluating family histories -- Table 19. Pedigree symbols-Common symbols and definitions -- Table 20. Pedigree symbols-Line definitions -- Table 21. Pedigree symbols-evaluation and testing information -- Table 22. Physical examination-body region (Cephalad to Caudad) -- Table 23. Physical examination-syndrome -- Table 24. Risk estimation models -- Table 25. Screening, surveillance, and diagnostic tests for cancer -- Table 26. Physiologic imaging tests for PCC/PGL/neuroendocrine tumors -- Table 27. Management of known alterations -- Section D: Tumors-Syndromes-Genes -- Table 28. Tumors, syndromes, genes -- Table 29. Syndromes, tumors, genes -- Table 30. Genes, tumors, syndromes.