539042765

Systems biology : properties of reconstructed networks / Bernhard Ø. Palsson

1. publ., Repr.

Englisch

Cambridge [u.a.] : Cambridge University Press, 2007

XII, 322 Seiten : Ill., graph. Darst.

2005035008

Literaturangaben und Literaturverz. S. 299 - 315

0-521-85903-4

978-0-521-85903-5

Preface; 1. Introduction; 2. Basic concepts in systems biology; Part I. Reconstruction of Biochemical Networks: 3. Metabolic networks; 4. Regulatory networks; 5. Signalling networks; Part II. Mathematical Representation of Reconstructed Networks: 6. Basic features of S; 7. Topological properties; 8. Fundamental subspaces; 9. Null space of S; 10. The left null space of S; 11. The row and column spaces of S; Part III. Capabilities of Reconstructed Networks: 12. Dual causality; 13. Properties of solution spaces; 14. Sampling properties of solution spaces; 15. Finding functional states; 16. Parametric sensitivity; 17. Epilogue; Appendix A. Nomenclature and abbreviations; Appendix B. E. coli core metabolic network; Bibliography; Index.

9780521859035

*Systembiologie

*Systembiologie

*Computational biology ; Genomics ; Bioinformatics

*Systems Biology

*Computational biology ; Genomics ; Bioinformatics

Klassifikation der Library of Congress: QH324.2

Dewey Dezimal-Klassifikation: 572.80285;

Regensburger Verbund-Klassifikation: WC 7700: W Biologie / WC Methoden / WC 7000 Biometrie, Biomathematik / Bioinformatik

Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The new discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook, the first devoted to systems biology, describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. ...

http://www.loc.gov/catdir/enhancements/fy0633/2005035008-d.html [Publisher description]

http://www.loc.gov/catdir/enhancements/fy0659/2005035008-d.html [Publisher description]

http://www.loc.gov/catdir/enhancements/fy0659/2005035008-t.html [Table of contents]

http://www.loc.gov/catdir/enhancements/fy0733/2005035008-b.html [Contributor biographical information]

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