PPN: | 883419408 |
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Sprache/n: | Englisch |
Veröffentlichungsangabe: | Cambridge : Cambridge University Press, 2011 |
Umfang: | 1 Online-Ressource (332 p.) |
Anmerkung: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
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ISBN: | 978-0-511-73617-9 : ebook |
Identifier: | DOI: 10.1017/CBO9780511736179 |
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Mehr zum Thema: | Klassifikation der Library of Congress: QH324.2Mathematics Subject Classification: *92-02Mathematics Subject Classification: 92B20Mathematics Subject Classification: 92C42Mathematics Subject Classification: 92C30Mathematics Subject Classification: 92C45Mathematics Subject Classification: 00A72 |
Inhalt: | Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard Ø. Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dynamic models using metabolomic and fluxomic data. The Mass Action Stoichiometric Simulation (MASS) procedure can be used for any cellular process for which data is available and allows a scalable step-by-step approach to the practical construction of network models. Specifically, it can treat integrated processes that need explicit accounting of small molecules and protein, which allows simulation at the molecular level. The material has been class-tested by the author at both the undergraduate and graduate level. All computations in the text are available online in MATLAB and MATHEMATICA® workbooks, allowing hands-on practice with the material |
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Anmerkung: | Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. |
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