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ABO-incompatible heart transplantation in children—a systematic review of current practice

  • Review Article
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Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Pediatric heart transplantation has significantly improved in the survival of children with cardiomyopathy and/or complex congenital heart defects. With the increasing number of children needing transplantation, there is a growing demand for the organ, making it harder to cope with the increasing number of children on the waiting list. One of the advances that helped reduce the waiting list mortality significantly is the ability to transplant children from donors with ABO incompatibility. Modification of perfusion abilities and management of donor organ improves outcome in this select population, making ABO-incompatible transplantation an attractive option in the wider armamentarium available for pushing boundaries in these children without impacting on outcomes.

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Funding

No funding has been received for this study.

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Authors and Affiliations

  1. Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children, WC1N 3JH, London, UK

    Arun Beeman & Nagarajan Muthialu

Authors
  1. Arun Beeman
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  2. Nagarajan Muthialu
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Contributions

AB prepared the first version. NM being the senior author supervised and edited further to prepare the final version. Both authors were involved in further review and editing.

Corresponding author

Correspondence to Nagarajan Muthialu.

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The authors declare that there is no conflict of interest.

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Institutional board exempted this from the need for ethical approval in view of this being a review article.

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No direct patient-identifiable data involved. Institutional board exempted this from the need for informed consent.

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Beeman, A., Muthialu, N. ABO-incompatible heart transplantation in children—a systematic review of current practice. Indian J Thorac Cardiovasc Surg 36 (Suppl 2), 190–193 (2020). https://doi.org/10.1007/s12055-020-00971-8

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  • DOI: https://doi.org/10.1007/s12055-020-00971-8

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