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Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis

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Acknowledgments

Supported by IZKF Münster (Ha3/019/15) and KinderKrebsInitiative Buchholz Holm-Seppensen.

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    Authors and Affiliations

    1. Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany

      Martin Hasselblatt, Christian Thomas, Susanne Peetz-Dienhart & Yvonne Crede

    2. Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

      Volker Hovestadt

    3. German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany

      Volker Hovestadt, Daniel Schrimpf, Pascal Johann, Annika Wefers, David Capper, Andrey Korshunov, David T. W. Jones, Stefan M. Pfister & Marcel Kool

    4. Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany

      Daniel Schrimpf, Annika Wefers, David Capper & Andrey Korshunov

    5. Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany

      Daniel Schrimpf, Annika Wefers, David Capper & Andrey Korshunov

    6. Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany

      Pascal Johann, David T. W. Jones, Stefan M. Pfister & Marcel Kool

    7. Department of Pediatric Oncology and Hematology, University Hospital Heidelberg, Heidelberg, Germany

      Pascal Johann & Stefan M. Pfister

    8. Institute of Human Genetics, Christian-Albrechts-University Kiel, Kiel, Germany

      Susanne Bens & Reiner Siebert

    9. Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

      Florian Oyen & Reinhard Schneppenheim

    10. Department of Pathology, Stanford University School of Medicine, Palo Alto, CA, 94305, USA

      Hannes Vogel

    11. Department of Neuropathology, Regensburg University Hospital, Regensburg, Germany

      Markus J. Riemenschneider

    12. Department of Radiology, Oncology and Anatomic-Pathology Sciences, Sapienza University, Rome, Italy

      Manila Antonelli & Felice Giangaspero

    13. IRCCS Neuromed, Pozzilli, IS, Italy

      Manila Antonelli & Felice Giangaspero

    14. Institute of Pathology, St. Luke’s Medical Center, Quezon City, Philippines

      Marie Christine Bernardo

    15. Department of Pathology, Mayo Clinic, Rochester, MN, USA

      Caterina Giannini

    16. Section of Histopathology, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan

      Nasir Ud Din

    17. Division of Neuropathology, UCSF Medical Center, San Francisco, CA, USA

      Arie Perry

    18. Faculty of Medicine, Institute of Neuropathology, University of Duisburg-Essen, Essen, Germany

      Kathy Keyvani

    19. Division of Anatomical Pathology, Neuropathology Specialty Group, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada

      Frank van Landeghem

    20. Department of Pediatric Hematology and Oncology, University Hospital Motol, Charles University, 2nd Medical School, Prague, Czech Republic

      David Sumerauer

    21. 2nd Department of Pediatrics, Semmelweis University, 1094, Budapest, Hungary

      Peter Hauser

    22. Swabian Childrens’ Cancer Center, Childrens’ Hospital Augsburg and EU-RHAB Registry, Augsburg, Germany

      Michael C. Frühwald

    Authors
    1. Martin Hasselblatt
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    2. Christian Thomas
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    3. Volker Hovestadt
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    4. Daniel Schrimpf
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    5. Pascal Johann
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    6. Susanne Bens
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    7. Florian Oyen
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    8. Susanne Peetz-Dienhart
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    9. Yvonne Crede
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    10. Annika Wefers
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    11. Hannes Vogel
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    12. Markus J. Riemenschneider
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    13. Manila Antonelli
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    14. Felice Giangaspero
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    15. Marie Christine Bernardo
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    16. Caterina Giannini
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    17. Nasir Ud Din
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    18. Arie Perry
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    19. Kathy Keyvani
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    20. Frank van Landeghem
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    21. David Sumerauer
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    22. Peter Hauser
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    23. David Capper
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    24. Andrey Korshunov
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    25. David T. W. Jones
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    26. Stefan M. Pfister
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    27. Reinhard Schneppenheim
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    28. Reiner Siebert
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    29. Michael C. Frühwald
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    30. Marcel Kool
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    Corresponding author

    Correspondence to Martin Hasselblatt.

    Additional information

    M. Hasselblatt and C. Thomas contributed equally.

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    Cite this article

    Hasselblatt, M., Thomas, C., Hovestadt, V. et al. Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis. Acta Neuropathol 132, 149–151 (2016). https://doi.org/10.1007/s00401-016-1574-9

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    • DOI: https://doi.org/10.1007/s00401-016-1574-9

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