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Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study

Fig 8

Morphometric analyses in three litters of ZIKV-injected pregnant mouse females.

(A) Crown rump length (CRL). (B) Occipital-frontal diameter (OFD). (C) Cephalic proportion relative to body size as indicated by the ratio between OFD/CRL. All data are displayed in relation to an interval defined as the average ± three standard deviations from respective PBS-injected controls. Arrows in C indicate two conceptuses displaying marginal evidence for microcephaly. m, malformed conceptuses, ***p<0.001.

Fig 8

doi: https://doi.org/10.1371/journal.pntd.0005363.g008