Overview
- Editors:
-
-
Dieter Steinhilber
-
Goethe University Frankfurt, Institute of Pharmaceutical Chemistry, Frankfurt, Germany
- Summarizes the functions of lipoxygenases in health and inflammatory diseases
- Gives a comprehensive account of the role of lipoxygenase metabolites in pathophysiology
- Chapters cover role in diseases, such as cancer, asthma, skin and cardiovascular diseases, as well as in the resolution of inflammation
Access this book
Other ways to access
Table of contents (10 chapters)
-
-
-
- Oliver Werz, Olof Rådmark
Pages 7-29
-
- Agnes Rinaldo-Matthis, Jesper Z. Haeggström
Pages 31-46
-
- Hartmut Kühn, Felix Karst, Dagmar Heydeck
Pages 47-82
-
- Michael Holinstat, Katrin Niisuke, Benjamin E. Tourdot
Pages 83-99
-
- Andrés Laguna-Fernández, Marcelo H. Petri, Silke Thul, Magnus Bäck
Pages 101-130
-
- J. Roos, B. Kühn, J. Fettel, I. V. Maucher, M. Ruthardt, A. Kahnt et al.
Pages 131-157
-
- Peter Krieg, Gerhard Fürstenberger
Pages 159-183
-
- William S. Powell, Joshua Rokach
Pages 185-210
-
- Antonio Recchiuti, Eleonora Cianci, Felice Simiele, Mario Romano
Pages 211-239
-
Back Matter
Pages 241-245
About this book
Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.
Editors and Affiliations
-
Goethe University Frankfurt, Institute of Pharmaceutical Chemistry, Frankfurt, Germany
Dieter Steinhilber
About the editor
Prof. Dr. Dieter Steinhilber, born 1959, studied pharmacy at the University of Tübingen. After an assistantship there he spent a postdoc period with Prof. Bengt Samuelsson, Karolinska Institute, Stockholm from 1989 until 1991. In 1994 he received an associated professorship and since 2000 he is a full professor for Pharmaceutical Chemistry at the Johann Wolfgang Goethe University in Frankfurt am Main. From 1999 until 2008 he was the Director of this Institute. From 1999 to 2000 he was Dean of the faculty Biochemistry, Pharmacy and Food Chemistry and from 2008-2011 he was Dean of the Faculty Biochemistry, Chemistry and Pharmacy. Prof Steinhilber is the speaker of the International Research Training Group "Dr. Hans Kröner Graduiertenkolleg" funded by the Else Kröner Fresenius-Stiftung. Since 2007, he is also the chairman of the graduate centre FIRST. In 2002, he has been elected into the board of ZAFES. Since 2002 he is a member of the "Wehrmedizinischer Beirat" and starting from 2004, he holds a membership of the "DFG-Fachkollegium Medicine" and represents the Pharmaceutical Sciences in the board. Since 2005, he is chairman of the "Akademie für Pharmazeutische Weiterbildung der LAK Hessen". He is president of the German Pharmaceutical Society (DPhG) from 2012-2015.
