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Improved Hypertrophy of Future Remnant Liver after Portal Vein Embolization with Plugs, Coils and Particles

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Abstract

Purpose

To retrospectively analyze efficacy as measured by volume gain of future remnant liver (FRL) after right portal vein embolization (PVE) using particles only versus particles and additional central plug and/or coil (CP/C) embolization.

Methods

All patients who underwent PVE between July 2011 and December 2012 were retrospectively analyzed. Right PVE was performed either with particle-only (PO) embolization or additional CP/C embolization. All enrolled patients underwent computed tomography or magnetic resonance imaging before PVE and surgery. The images were used for volumetry of the FRL.

Results

Of 75 patients, 40 had PO and 35 CP/C embolization. Age, sex, and tumor entities did not differ significantly between the two groups. Tumor entities included cholangiocarcinoma (n = 52), metastasis from colorectal cancer (n = 14), hepatocellular carcinoma (n = 2), and others (n = 7). Time from PVE to preoperative imaging was similar in both groups. FRL volume before PVE was 329 ± 121 ml in the PO group and 333 ± 135 ml in the CP/C group, and 419 ± 135 ml and 492 ± 165 ml before operation. The average percentage volume gain was significantly higher in the CP/C group than in the PO group, with 53.3 ± 34.5 % versus 30.9 ± 28.8 % (p = 0.002).

Conclusion

Right PVE with additional CP/C embolization leads to a significantly higher gain in FRL volume than embolization with particles alone.

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Conflict of Interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany

    Dominik Geisel, Maciej-Janusz Powerski, Joost Wüstefeld, Timm Denecke & Bernhard Gebauer

  2. Department of General, Visceral and Transplantation Surgery, Charité, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany

    Maciej Malinowski, Victoria Heller & Martin Stockmann

Authors
  1. Dominik Geisel
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  2. Maciej Malinowski
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  3. Maciej-Janusz Powerski
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  4. Joost Wüstefeld
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  5. Victoria Heller
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  6. Timm Denecke
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  7. Martin Stockmann
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  8. Bernhard Gebauer
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Correspondence to Dominik Geisel.

Additional information

Dominik Geisel, Maciej Malinowski, Martin Stockmann and Bernhard Gebauer have contributed equally to this work.

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Geisel, D., Malinowski, M., Powerski, MJ. et al. Improved Hypertrophy of Future Remnant Liver after Portal Vein Embolization with Plugs, Coils and Particles. Cardiovasc Intervent Radiol 37, 1251–1258 (2014). https://doi.org/10.1007/s00270-013-0810-0

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  • DOI: https://doi.org/10.1007/s00270-013-0810-0

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