Abstract
Objective
To evaluate the validity of a single-stage dorsal inlay for recurrent peno-glandular stenosis following previous endourological or open urethroplastic surgery. Urethral glanular reconstruction included a deep dorsal incision followed by complete scar excision to create a deep groove presenting well-vascularized recipient bed ensuring appropriate graft healing.
Materials and methods
Between April 2002 and January 2008, a total of 34 patients (mean age 51.5 years, 14–85 years) were enrolled in the study. Congenital anomalies included hypospadia (n = 19, 53%) and epispadia (n = 2, 6%). Condition of strictures was either iatrogenic (n = 7), due to infection (n = 5), or traumatic (n = 1). Foreskin grafts were used in 13 cases, foreskin and buccal mucosa in one case, penile skin in 6 cases, and inguinal skin/thigh (harvested by electrodermatom) in 14 cases. The combination of meticulous scar excision with a deep incision of the glans was used to provide a well-vascularized grafting bed, thus ensuring excellent graft healing. The outcome analysis included urinary flow, urethral calibration >18 ch, voiding cystometry, and patient’s satisfaction in a follow-up regime every 3 months.
Results
The average graft length was 4.7 cm (median 8, range 1.5–14). Mean follow-up was 70 months. In 31 patients (91%), no recurrent glanular stenosis was observed resulting in a post-operative flow of average 26.2 ml/s (11–53). Three post-operative wound infections occurred resulting in stricture recurrence, which was treated with internal urethrotomy, buccal mucosa, or penile skin inlay, respectively. Cosmetic results were satisfactory in all patients. Post-operative voiding parameters were significantly improved (P < 0.001).
Conclusion
The single-stage dorsal inlay for reconstruction of peno-glandular stenosis represents a reliable method even if the urethral plate is severely scarred or has been excised during previous surgery. The good results imply that a well-vascularized graft and the technical approach seem to be more important than the substitute material.
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References
VanderBrink BA, Gitlin J, Palmer LS (2008) Uroflowmetry parameters before and after meatoplasty for primary symptomatic meatal stenosis in children. J Urol 179:2403–2406 (discussion 6)
Baskin LS, Duckett JW (1995) Buccal mucosa grafts in hypospadias surgery. Br J Urol 76(Suppl 3):23–30
Schwentner C, Gozzi C, Lunacek A et al (2006) Interim outcome of the single stage dorsal inlay skin graft for complex hypospadias reoperations. J Urol 175:1872–1876 (discussion 6–7)
Dalpiaz O, Kerschbaumer A, Pelzer A et al (2008) Single-stage dorsal inlay split-skin graft for salvage anterior urethral reconstruction. BJU Int 101:1565–1570
Ye WJ, Ping P, Liu YD, Li Z, Huang YR (2008) Single stage dorsal inlay buccal mucosal graft with tubularized incised urethral plate technique for hypospadias reoperations. Asian J Androl 10:682–686
Andrich DE, Mundy AR (2008) What is the best technique for urethroplasty? Eur Urol 54:1031–1041
Stein R, Schroder A, Thuroff JW (2007) Use of buccal mucosa in urethral surgery. Urologe A 46:1657–1663
Onol SY, Onol FF, Onur S, Inal H, Akbas A, Kose O (2008) Reconstruction of strictures of the fossa navicularis and meatus with transverse island fasciocutaneous penile flap. J Urol 179:1437–1440
Morey A (2009) Urethral stricture is now an open surgical disease. J Urol 181:953–954
Morey AF, Lin HC, DeRosa CA, Griffith BC (2007) Fossa navicularis reconstruction: impact of stricture length on outcomes and assessment of extended meatotomy (first stage Johanson) maneuver. J Urol 177:184–187 (discussion 7)
Gozzi C, Tritschler S, Bastian PJ, Stief CG (2008) Urethral strictures. MMW Fortschr Med 150:37–39
Jordan GH (1987) Reconstruction of the fossa navicularis. J Urol 138:102–104
Das SK, Kumar A, Sharma GK et al (2009) Lingual mucosal graft urethroplasty for anterior urethral strictures. Urology 73:105–108
Abdel-Galil K, Eardley I, Loukota R (2009) Buccal mucosal grafts for urethroplasty: comparison of postoperative oral and perineal morbidity. Ann R Coll Surg Engl 91:116–117
Dublin N, Stewart LH (2004) Oral complications after buccal mucosal graft harvest for urethroplasty. BJU Int 94:867–869
Dubey D, Vijjan V, Kapoor R et al (2007) Dorsal onlay buccal mucosa versus penile skin flap urethroplasty for anterior urethral strictures: results from a randomized prospective trial. J Urol 178:2466–2469
Raber M, Naspro R, Scapaticci E et al (2005) Dorsal onlay graft urethroplasty using penile skin or buccal mucosa for repair of bulbar urethral stricture: results of a prospective single center study. Eur Urol 48:1013–1017
Barbagli G, Lazzeri M (2007) Surgical treatment of anterior urethral stricture diseases: brief overview. Int Braz J Urol 33:461–469
Li Q, Li S, Chen W et al (2005) Combined buccal mucosa graft and local flap for urethral reconstruction in various forms of hyposapdias. J Urol 174:690–692
Barbagli G, De Angelis M, Romano G, Ciabatti PG, Lazzeri M (2008) The use of lingual mucosal graft in adult anterior urethroplasty: surgical steps and short-term outcome. Eur Urol 54:671–676
Bhargava S, Patterson JM, Inman RD, MacNeil S, Chapple CR (2008) Tissue-engineered buccal mucosa urethroplasty-clinical outcomes. Eur Urol 53:1263–1269
Hauser S, Bastian PJ, Fechner G, Muller SC (2006) Small intestine submucosa in urethral stricture repair in a consecutive series. Urology 68:263–266
Barbagli G, De Angelis M, Palminteri E, Lazzeri M (2006) Failed hypospadias repair presenting in adults. Eur Urol 49:887–894 (discussion 95)
Wessells H, McAninch JW (1996) Use of free grafts in urethral stricture reconstruction. J Urol 155:1912–1915
Das S, Tunuguntla HS (2000) Balanitis xerotica obliterans—a review. World J Urol 18:382–387
Manzoni G, Bracka A, Palminteri E, Marrocco G (2004) Hypospadias surgery: when, what and by whom? BJU Int 94:1188–1195
Virasoro R, Eltahawy EA, Jordan GH (2007) Long-term follow-up for reconstruction of strictures of the fossa navicularis with a single technique. BJU Int 100:1143–1145
Venn SN, Mundy AR (1998) Urethroplasty for balanitis xerotica obliterans. Br J Urol 81:735–737
Nahas BW, Hart AJ (1999) Re: reconstruction of resistant strictures of the fossa navicularis, meatus. J Urol 161:924
Levine LA, Strom KH, Lux MM (2007) Buccal mucosa graft urethroplasty for anterior urethral stricture repair: evaluation of the impact of stricture location and lichen sclerosus on surgical outcome. J Urol 178:2011–2015
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Bastian, P.J., Mayer, M., Tritschler, S. et al. Single-stage dorsal inlay for reconstruction of recurrent peno-glandular stenosis. World J Urol 30, 715–721 (2012). https://doi.org/10.1007/s00345-011-0770-4
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DOI: https://doi.org/10.1007/s00345-011-0770-4