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Aneurysm embolization grade: a predictive tool for aneurysm recurrence after coil embolization

  • Clinical Article - Vascular
  • Published:
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Abstract

Background

Coil embolization has gained importance in the management of intracranial aneurysms over the past decade. However, the recurrence risk after embolization mandates closer follow-up than surgical clip ligation. Currently, there is no reliable system for predicting aneurysm sac thrombosis. An aneurysm embolization grade (AEG) reported previously by the senior author (EMD) has been proposed as a tool for predicting the durability of aneurysm occlusion based on hemodynamic characteristics. Here, we present our internal validity results.

Methods

AEG and Raymond–Roy Occlusion Classification (RROC) scores were prospectively assigned to all aneurysms coiled from June 2008 to June 2011. The prospectively assigned AEG and RROC scores from the cerebral angiograms were collected for data analysis and validity assessment of the AEG system. 110 consecutive patients who had aneurysm coil embolization were included in this study.

Results

The post-coiling AEG significantly predicted follow-up angiographic filling characteristics. Pairwise comparisons revealed that the follow-up AEG for those initially scored ‘A’ (complete obliteration) was significantly better than the contrast-flow groups. Significant differences were also noted between contrast-stasis and contrast-flow groups. A pairwise comparison between RROC scores demonstrated that only the RROC Type 1 could be used to predict follow-up occlusion durability. Stent placement in wide-neck aneurysms had no effect on initial AEG, RROC, or long-term occlusion durability. Packing density significantly predicted initial AEG and RROC, but had no effect on long-term occlusion.

Conclusions

The AEG system is uniquely based on angiographic filling characteristics of the aneurysm, and this study demonstrated its high predictive value for determining aneurysm sac thrombosis. Assigning an AEG to the aneurysm can guide the neurointerventionalist in discussions with the patient regarding the probability of aneurysm recurrence and potential need for retreatment.

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Acknowledgments

The authors would like to thank Margaret Riordan (Department of Neurosurgery, SUNY Upstate Medical University, Syracuse NY) and Sarah Dewitt (Department of Neurosurgery, SUNY Upstate Medical University, Syracuse NY) for their assistance with the collection of data for this manuscript.

Conflicts of interest

Eric M. Deshaies is a Physician Consultant for eV3/Covidien, Integra, and Microvention.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, SUNY Upstate Medical University, Syracuse, NY, USA

    Amit Singla, Mark R. Villwock & Eric M. Deshaies

  2. Department of Neurosurgery, Albany Medical Center, Albany, NY, USA

    Walter Jacobsen

  3. SUNY Upstate Neurovascular Institute, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY, 13210, USA

    Eric M. Deshaies

  4. Cerebrovascular, Endovascular, and Skull Base Neurosurgery, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY, 13210, USA

    Eric M. Deshaies

  5. Neuroendovascular Fellowship Program, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY, 13210, USA

    Eric M. Deshaies

  6. Neurosurgery, Neuroscience & Physiology, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY, 13210, USA

    Eric M. Deshaies

Authors
  1. Amit Singla
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  2. Mark R. Villwock
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  3. Walter Jacobsen
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  4. Eric M. Deshaies
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Corresponding author

Correspondence to Eric M. Deshaies.

Additional information

The Aneurysm Embolization Grade was discussed in a presentation by the senior author (EMD) titled “Controversies in Aneurysm Therapy” at the Second Annual International Congress of Interventional Neurology, September 6–8 2012, Minneapolis, Minnesota, USA.

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Singla, A., Villwock, M.R., Jacobsen, W. et al. Aneurysm embolization grade: a predictive tool for aneurysm recurrence after coil embolization. Acta Neurochir 155, 231–236 (2013). https://doi.org/10.1007/s00701-012-1554-3

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  • DOI: https://doi.org/10.1007/s00701-012-1554-3

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