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Factor analysis of modifiable cardiovascular risk factors and prevalence of metabolic syndrome in adult Taiwanese

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Abstract

To assess the clustering of modifiable cardiovascular risk factors among Taiwanese adults, we evaluated 579 healthy participants who underwent health examinations between May and December 2007. Exploratory factor analysis was used to examine risk factor clustering. Smoking, alcohol intake, exercise habits, body mass index, waist circumference, total cholesterol, triglycerides, high- and low-density lipoprotein cholesterol, fasting glucose, uric acid, serum hepatic enzymes, and mean arterial pressure were assessed. Separate factor analyses assessed total and low-density lipoprotein cholesterol. Principal components analysis identified five factors for a model without low-density lipoprotein cholesterol and four factors for a model without total cholesterol. Four common factors in both models explained between 51.1 and 51.8% of variance in the original 14 factors. Metabolic factors, hematological factors (white blood cells and platelets), lifestyle factors (smoking and alcohol consumption), and exercise habits and fasting blood glucose explained about 20, 11, 10, 10% of total variance, respectively. In the model without low-density lipoprotein cholesterol, total cholesterol factor explained 8.83% of variance. This study confirmed clustering of established metabolic syndrome components and revealed additional associated cardiovascular disease risk factors, including lifestyle factors, exercise and total cholesterol, which should be targeted in prevention efforts.

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Acknowledgments

This study was supported by Cheng Ching Hospital and the authors appreciate the expert assistance of all colleagues from the Health Management Center of Cheng Ching Hospital. Permission was granted for the acknowledgement of staff. Funding for this study was provided by Cheng Ching Hospital and no other funding support was received.

Disclosure

The authors have no conflicts of interest to disclose.

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Authors and Affiliations

  1. Department of Family Medicine, Cheng Ching Hospital, No. 118, sec. 3, Chung-Kang Road, Taichung, 40764, Taiwan, ROC

    Chung-Huang Tsai

  2. Graduate Institute of Biochemical Sciences and Technology, Chaoyang University of Technology, 168, Jifong East Road, Wufong Township, Taichung, 41349, Taiwan, ROC

    Chung-Huang Tsai & Hsin-Sheng Tsay

  3. Graduate Institute of Biostatistics & Chinese Medicine Science, China Medical University & Hospital, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC

    Tsai-Chung Li

  4. Biostatistics Center, China Medical University & Hospital, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC

    Tsai-Chung Li

  5. Department of Family Medicine, China Medical University & Hospital, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC

    Cheng-Chieh Lin

  6. Medical Research Department, China Medical University & Hospital, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC

    Cheng-Chieh Lin

  7. School and Graduate Institute of Health Care Administration, College of Public Health, China Medical University & Hospital, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC

    Cheng-Chieh Lin

  8. Department of Healthcare Administration, College of Health Science, Asia University, No. 500, Lioufeng Road, Wufeng, Taichung, 41354, Taiwan, ROC

    Cheng-Chieh Lin

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  1. Chung-Huang Tsai
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  2. Tsai-Chung Li
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Correspondence to Hsin-Sheng Tsay.

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Tsai, CH., Li, TC., Lin, CC. et al. Factor analysis of modifiable cardiovascular risk factors and prevalence of metabolic syndrome in adult Taiwanese. Endocrine 40, 256–264 (2011). https://doi.org/10.1007/s12020-011-9466-1

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  • DOI: https://doi.org/10.1007/s12020-011-9466-1

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