Molecular Cell
Volume 47, Issue 6, 28 September 2012, Pages 825-826
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RNase E Finds Some sRNAs Stimulating

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In this issue of Molecular Cell, Bandyra et al. (2012) describe how a bacterial sRNA can lead to degradation of an mRNA by pairing within the coding region of the mRNA; the 5′ monophosphate end of the sRNA activates RNase E, leading to rapid cleavage of the paired mRNA.

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