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Cell biology

Phosphate on, rubbish out

A previously unknown way in which cells mark proteins for destruction has been found in bacteria — phosphorylation of the amino acid arginine targets proteins for degradation by protease enzymes. See Article p.48

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Figure 1: Protein destruction by protease enzymes.

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Correspondence to Susan Gottesman.

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Cell biology: Destruction deconstructed

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Tripathi, A., Gottesman, S. Phosphate on, rubbish out. Nature 539, 38–39 (2016). https://doi.org/10.1038/539038a

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