New work has identified networks of protein interactions at the transition zones of cilia. These discoveries provide insights into the molecular pathogenesis of ciliopathies and illustrate the power of linking proteomics technologies with human genetics to uncover critical disease pathways.
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Benzing, T., Schermer, B. Transition zone proteins and cilia dynamics. Nat Genet 43, 723–724 (2011). https://doi.org/10.1038/ng.896
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DOI: https://doi.org/10.1038/ng.896
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