Issue 85, 2013
From the journal:

Chemical Communications

A Pt-nanoparticle electrocatalytic assay used for PCR-free sensitive telomerase detection†

Zhijun Zhang,ab   Li Wu,ab   Jiasi Wang,ab   Jinsong Rena  and  Xiaogang Qu*a  

* Corresponding authors

a Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China
E-mail: xqu@ciac.ac.cn

b University of Chinese Academy of Sciences, Beijing, P.R. China
Fax: +86 431-85262656

Abstract

An electrocatalytic assay was developed for telomerase activity detection by using superior catalytic properties of Pt nanoparticles. This design was PCR-free, and highly sensitive for telomerase with a detection limit of less than 2 cells.

Graphical abstract: A Pt-nanoparticle electrocatalytic assay used for PCR-free sensitive telomerase detection

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Article information

DOI
https://doi.org/10.1039/C3CC45904G
Article type
Communication
Submitted
02 Aug 2013
Accepted
04 Sep 2013
First published
05 Sep 2013

Chem. Commun., 2013,49, 9986-9988

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A Pt-nanoparticle electrocatalytic assay used for PCR-free sensitive telomerase detection

Z. Zhang, L. Wu, J. Wang, J. Ren and X. Qu, Chem. Commun., 2013, 49, 9986 DOI: 10.1039/C3CC45904G

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