Noncontact diffuse optical tomography

Jorge Ripoll; Ralf B. Schulz; Vasilis Ntziachristos

doi:10.1117/12.578917

20 August 2004 Noncontact diffuse optical tomography

Jorge Ripoll, Ralf B. Schulz, Vasilis Ntziachristos

Proceedings Volume 5474, Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V; (2004) https://doi.org/10.1117/12.578917
Event: Saratov Fall Meeting 2003, 2003, Saratov, Russian Federation

Abstract

We present a simple and novel theoretical approach for modeling the intensity distribution from an arbitrarily shaped turbid volume in a non-contact geometry by considering diffuse light propagation in free-space. Optical tomography of turbid media has so far been limited by systems that require fixed geometries or fiber measurements. This novel theory is validated with experiments for a diffusive volume of known geometry in a non-contact situation, both with and without the presence of an embedded absorber. We also present a system that records non-contact optical measurements from diffuse media of arbitrary shapes and retrieves the three-dimensional surface information of the diffuse medium. This approach offers significant experimental simplicity and yields high-information content datasets. The performance of this novel tomographic approach is demonstrated with experimental reconstructions of phantoms. Finally, the implications of this new formulation in the context of optical tomography in turbid media are discussed.

Citation Download Citation

Jorge Ripoll, Ralf B. Schulz, and Vasilis Ntziachristos "Noncontact diffuse optical tomography", Proc. SPIE 5474, Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V, (20 August 2004); https://doi.org/10.1117/12.578917

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available