Contactless photoacoustic imaging of biological samples

Thomas Berer; Armin Hochreiner; Hubert Grün; Peter Burgholzer

doi:10.1117/12.908483

23 February 2012 Contactless photoacoustic imaging of biological samples

Thomas Berer, Armin Hochreiner, Hubert Grün, Peter Burgholzer

Proceedings Volume 8223, Photons Plus Ultrasound: Imaging and Sensing 2012; 82231G (2012) https://doi.org/10.1117/12.908483
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

In this paper we report on remote photoacoustic imaging using an interferometric technique. By utilizing a two-wave mixing interferometer ultrasonic displacements are measured without any physical contact to the sample. This technique allows measurement of the displacements also on rough surfaces. Mixing a plane reference beam with the speckled beam originating from the sample surface is done in a Bi₁₂SiO₂₀ photorefractive crystal. After data acquisition the structure of the specimen is reconstructed using a Fourier-domain synthetic focusing aperture technique. We show three-dimensional imaging on tissue-mimicking phantoms and biological samples. Furthermore, we show remote photoacoustic measurements on a human forearm in-vivo.

Citation Download Citation

Thomas Berer, Armin Hochreiner, Hubert Grün, and Peter Burgholzer "Contactless photoacoustic imaging of biological samples", Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82231G (23 February 2012); https://doi.org/10.1117/12.908483

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