Acute Kidney Injury in Patients with Newly Diagnosed High-Grade Hematological Malignancies: Impact on Remission and Survival
Figure 2
Effects of RIFLE classification on complete remission at 6 months.
RIFLE classification scheme for acute kidney injury (AKI). The classification system includes separate criteria for creatinine and urine output (UO). A patient can fulfill the criteria through changes in serum creatinine (SCreat) or changes in UO, or both within 7 days. The criteria that lead to the worst possible classification should be used. R, RIFLE risk category: increased SCreat×1.5 or Glomerular filtration Rate (GFR) decrease >25% or UO <0.5 ml/kg/h×6 hours. I, RIFLE injury category: increased SCreat×2 or GFR decrease >50% or UO <0.5 ml/kg/h×12 hours. F, RIFLE failure category: increased SCreat×3 or SCreat greater than 4.0 mg/dl (350 µmol/l) with an acute increase of at least 0.5 mg/dl (44 µmol/l) or GFR decrease >75% or UO <0.3 ml/kg/h×24 hours or anuria×12 hours.