Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor
Figure 1
Effects of sample type on multimer staining results.
For donors with 3 sample types (WBM, A, G), percentages of multimer-positive cells (sum of all matched alleles) in CD3+CD8+ T cells were compared for (A) CMV-seropositive (n = 14) and (B) EBV-seropositive (n = 11) donors. Inclusion criteria for the analysis were availability of serostatus and a staining result ≥0.1%. In the majority of samples, the staining results for each sample type remained in the same range. Sample sources: (A) apheresis tubing set, (G) graft, (WBM) mobilized whole blood on day of apheresis.