Références
Rashad S, Revell P, Hemingway A, et al. Effect of non-steroidal anti-inflamatory drugs on the course of osteoarthritis. Lancet 1989; 2: 519–22
Zenz M, Willweber-Strumpf A. Opiophobia and cancer pain in Europe. Lancet 1993; 341: 1075–76
Dubner R, Max MB. Antidepressants and the relief of neuropathic pain: evidence for noradrenergic mechanisms. In: Besson J-M, Guilbaud G, editors. Towards the use of noradrenergic agonists for the treatment of pain. 1992: 211–8
Kayser V, Besson J-M, Guilbaud G. Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat. Eur J Pharmacol 1992; 224: 83–8
Raffa RB, Friderichs E, Reimann W, et al. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an atypical opioid analgesic. J Pharmacol Exp Ther 1992; 260: 275–85
Dayer P. The pharmacology of tramadol. Drugs 1994; 47 Suppl. 1:3–7
Vickers MD, O’Flaherty D, Szekely SM, et al. Tramadol: pain relief by an opioid without depression of respiration. Anaesthesia 1992; 47: 291–6
Keup W. Missbrauchsmuster bei Abhängigkeit von Alkohol, Medikamenten und Drogen Frühwarnsystem-Daten für die Bundesrepublik Deutschland 1976–1990; Freiburg im Breisgau, Allemagne: Lambertus Verlag, 1993: 48–145
Collart L, Luthy C, Dayer P. Partial inhibition of tramadol antinociceptive effect by naloxone in man. Proceedings of the British Pharmacological Society; 1992 Sep: London. Br J Clin Pharmacol 1993; 35: 73
Desmeules J, Piguet V, Collart L, et al. Contribution of mono-aminergic modulation in tramadol analgesic effect [Abstract]. Clin Pharmacol Ther 1994; 55(2): 151
Raffa RB, Friderichs E, Reimann G, et al. Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol. J Pharmacol Exp Ther 1993; 267(1): 331–40
Lehmann KA. Tramadol for the management of acute pain. Drugs 1994; 47 Suppl. 1: 19–32
Göbel H, Stadler TH. Traitement des douleurs post-zostériennes par le tramadol: résultats d’une étude pilote ouverte versus clomipramine avec ou sans lévomépromazine. Drugs 1997; 53 Suppl. 2: 34–9
Bono AV, Cuffari S. Efficacité et tolérance du tramadol dans les douleurs néoplasiques: étude comparative par rapport à la buprénorphine. Drugs 1997; 53 Suppl. 2: 40–49
Cossmann M, Kohnen C, Langford R, et al. Tolérance et sécurité d’emploi du tramadol: résultats des études internationales et données de la pharmacovigilance. Drugs 1997; 53 Suppl. 2: 50–62
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Besson, JM. Apport du tramadol dans la stratégie thérapeutique de la douleur. Drugs 53 (Suppl 2), 63–64 (1997). https://doi.org/10.2165/00003495-199700532-00011
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DOI: https://doi.org/10.2165/00003495-199700532-00011