1471-2180-7-49-5.jpg (32.06 kB)

Prevention of WNV-induced cell death by pan-caspase inhibition

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posted on 2011-12-30, 18:29 authored by Malte C Kleinschmidt, Martin Michaelis, Henry Ogbomo, Hans-Wilhelm Doerr, Jindrich Cinatl

Copyright information:

Taken from "Inhibition of apoptosis prevents West Nile virus induced cell death"

http://www.biomedcentral.com/1471-2180/7/49

BMC Microbiology 2007;7():49-49.

Published online 29 May 2007

PMCID:PMC1891299.

Inhibition of virus-induced cell death indicated by trypan blue staining of WNV (MOI 0.1)-infected T98G cell cultures by pan-caspase inhibitor z-VAD-fmk (100 μM) relative to mock-infected cells (A) and the effect of different z-VAD-fmk concentrations on infectious virus titre production (TCID/ml, 48 h p.i.) after infection at MOI 0.1 (B). Values represent mean (± SD) from three independent experiments. *p < 0.05 compared to untreated virus control.