1471-2180-7-49-3.jpg (60.96 kB)

WNV infection induces caspase activation and cytochrome c release

figure

posted on 2011-12-30, 18:28 authored by Malte C Kleinschmidt, Martin Michaelis, Henry Ogbomo, Hans-Wilhelm Doerr, Jindrich Cinatl

Copyright information:

Taken from "Inhibition of apoptosis prevents West Nile virus induced cell death"

http://www.biomedcentral.com/1471-2180/7/49

BMC Microbiology 2007;7():49-49.

Published online 29 May 2007

PMCID:PMC1891299.

Cellular levels of procaspase-8, cleaved caspase-9, BID and procaspase-3 during WNV-infection (A), release of cytochrome c from mitochondria into the cytoplasma (B) and caspase-3 activation (C) in WNV infected cells (all MOI 1). The band in A marked with * resulted from unspecific antibody binding. Blots shown are representative for a set of three different experiments. Values represent mean (± SD) from three independent experiments. *p < 0.05 compared to mock-infected cultures.