Prenatal Restraint Stress Generates Two Distinct Behavioral and Neurochemical Profiles in Male and Female Rats
Figure 7
Gender effect in the effect of PRS on 1S,3R-ACPD or DHPG-stimulated PI hydrolysis in slices prepared from the dorsal or the ventral hippocampus.
Data obtained from slices of male and female rat hippocampi are shown in (A,C) and (B,D), respectively. Values are expressed as means±S.E.M. of 6–9 measurements from 2–3 independent experiments. ANOVA for group×region: F(1,8) = 4.97, p<0.05 for 1S,3R-ACPD and F(1,8) = 128.79, p<0.05 for DHPG in males; F (1,8) = 7.54, p<0.05 for 1S,3R-ACPD in females). * p<0.05 Newman-Keul's test post-hoc for PRS vs. control animals; # p<0.05 ventral vs. dorsal hippocampus (n = 5 rats per group).