Abstract
To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%). Having low initial titers on Venereal Disease Research Laboratory test and living in a village where yaws baseline incidence was high were associated with increased likelihood of treatment failure.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Anti-Bacterial Agents / therapeutic use*
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Child
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Child, Preschool
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Cohort Studies
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Female
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Humans
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Male
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Penicillin G Benzathine / therapeutic use*
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Prognosis
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Skin Ulcer / drug therapy
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Skin Ulcer / pathology
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Treatment Failure
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Treatment Outcome
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Yaws / diagnosis*
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Yaws / drug therapy*
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Yaws / epidemiology
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Yaws / pathology
Substances
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Anti-Bacterial Agents
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Penicillin G Benzathine