Comparison of the BD Max methicillin-resistant Staphylococcus aureus (MRSA) assay and the BD GeneOhm MRSA achromopeptidase assay with direct- and enriched-culture techniques using clinical specimens for detection of MRSA

Alexander H Dalpke; Marjeta Hofko; Stefan Zimmermann

doi:10.1128/JCM.01496-12

Comparison of the BD Max methicillin-resistant Staphylococcus aureus (MRSA) assay and the BD GeneOhm MRSA achromopeptidase assay with direct- and enriched-culture techniques using clinical specimens for detection of MRSA

J Clin Microbiol. 2012 Oct;50(10):3365-7. doi: 10.1128/JCM.01496-12. Epub 2012 Jul 18.

Authors

Alexander H Dalpke¹, Marjeta Hofko, Stefan Zimmermann

Affiliation

¹ Department of Infectious Diseases, University Hospital Heidelberg, Heidelberg, Germany. alexander.dalpke@med.uni-heidelberg.de

Abstract

We evaluated the new, fully automated molecular BD Max methicillin-resistant Staphylococcus aureus (MRSA) assay for detection of methicillin-resistant S. aureus in a low-prevalence (4.1%) setting. Sensitivity, specificity, and positive and negative predictive values were 93.9%, 99.2%, 83.8%, and 99.7%, respectively. The assay reported fewer unresolved results than the BD GeneOhm MRSA ACP assay.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Automation / methods
Humans
Methicillin-Resistant Staphylococcus aureus / genetics
Methicillin-Resistant Staphylococcus aureus / isolation & purification*
Microbial Sensitivity Tests / methods
Molecular Diagnostic Techniques / methods*
Predictive Value of Tests
Sensitivity and Specificity
Staphylococcal Infections / microbiology*