Outcomes after recto-anastomosis fistula repair in patients who underwent radical prostatectomy for prostate cancer

BJU Int. 2014 Apr;113(4):568-73. doi: 10.1111/bju.12254. Epub 2013 Nov 21.

Abstract

Objectives: To assess fistula recurrence rate and health-related quality of life (HRQL) after repair, as well as the impact on continence and erection in patients with recto-anastomotic fistula after radical prostatectomy (RP). In recent publications, the numbers of cases of recto-urinary fistulae after RP are relatively small. Success rates at fistula closure are good; however, data about functional outcomes and HRQL are more restricted.

Patients and methods: A retrospective study of patients treated for recto-urethral fistulae after RP between 1993 and 2008. All 17 patients were assessed for fistula recurrence in 2007 and received a standardised non-validated questionnaire to assess HRQL in 2011; furthermore, a patient's chart review was performed.

Surgical technique: fistula closure was abdominal in 10 patients, perineal in five and combined abdominal and perineal in two, some with tissue interposition.

Results: In 2007, follow-up was available for 14 patients, one was deceased and two were lost to follow-up. The mean follow-up was 73.3 months and the mean patient age was 63 years. In two of the 17 patients, rectal injury during the initial surgery was reported; another three had undergone adjuvant radiation therapy (18%). In 2011, another two patients were deceased; the mean (range) follow-up was 99.5 (44-184) months. There was a great improvement in HRQL as compared with before surgery in seven of the 12 evaluable patients, a slight improvement in one and no change in three. In all, eight of the 12 patients were very satisfied with the surgery and four were satisfied.

Conclusion: Perineal or abdominal fistula repair yields excellent success rates and high patient satisfaction. However, urinary incontinence can be found in some patients postoperatively, requiring further treatment.

Keywords: fistula; prostate cancer; reconstruction; urorectal fistula repair.

MeSH terms

  • Aged
  • Anastomosis, Surgical
  • Humans
  • Male
  • Middle Aged
  • Prostatectomy / adverse effects*
  • Prostatectomy / methods
  • Prostatic Neoplasms / surgery*
  • Quality of Life
  • Rectal Fistula / etiology
  • Rectal Fistula / surgery*
  • Recurrence
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome
  • Urethral Diseases / etiology
  • Urethral Diseases / surgery*
  • Urinary Fistula / etiology
  • Urinary Fistula / surgery*
  • Urinary Incontinence / etiology