Marine Drugs (Sep 2009)

Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum

  • Jyh-Horng Sheu,
  • Yang-Chang Wu,
  • Wei-Hsien Wang,
  • Mei-Ru Lin,
  • Ping-Jyun Sung,
  • Bo-Yuan Chen,
  • Tsong-Long Hwang

DOI
https://doi.org/10.3390/md7030472
Journal volume & issue
Vol. 7, no. 3
pp. 472 – 482

Abstract

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Two new briarane-related diterpenoids, designated as excavatoids E (1) andF (2), were isolated from the cultured octocoral Briareum excavatum. The structures ofcompounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes 1 and 2 were found to exhibit moderate inhibitory effects on elastase release by human neutrophils.

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