Emerging Infectious Diseases (May 2017)

Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA

  • John Papp,
  • A. Jeanine Abrams,
  • Evelyn Nash,
  • Alan R. Katz,
  • Robert D. Kirkcaldy,
  • Norman P. O’Connor,
  • Pamela S. O’Brien,
  • Derek H. Harauchi,
  • Eloisa V. Maningas,
  • Olusegun O. Soge,
  • Ellen N. Kersh,
  • Alan Komeya,
  • Juval E. Tomas,
  • Glenn M. Wasserman,
  • Gail Y. Kunimoto,
  • David L. Trees,
  • A. Christian Whelen

DOI
https://doi.org/10.3201/eid2305.170088
Journal volume & issue
Vol. 23, no. 5
pp. 830 – 832

Abstract

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During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.

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