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  • 1
    Online Resource
    Online Resource
    Cambridge, UK ; New York : Cambridge University Press
    UID:
    b3kat_BV035413331
    Format: 1 Online-Ressource (ix, 285 Seiten) , 26 cm
    Edition: Online_Ausgabe Boulder, Colo NetLibrary 2005 E-Books von NetLibrary Sonstige Standardnummer des Gesamttitels: 22382847
    ISBN: 0511077890
    Note: Includes bibliographical references (p. [264]-276) and index , 1. The situation and tasks of the philosophy of art -- 2. Representation, imitation, and resemblance -- 3. Beauty and form -- 4. Expression -- 5. Originality and imagination -- 6. Understanding art -- 7. Identifying and evaluating art -- 8. Art and emotion -- 9. Art and morality -- 10. Art and society: some contemporary practices of art -- 11. Epilogue: the evidence of things not seen
    Additional Edition: Reproduktion von Eldridge, Richard Thomas, 1953- An introduction to the philosophy of art 2003
    Language: English
    Subjects: Philosophy
    RVK:
    Keywords: Ästhetik ; Kunst ; Philosophie ; Einführung ; Electronic books. ; Electronic books ; Electronic books ; Electronic books. ; Electronic books. ; Electronic books ; Einführung
    URL: Full text  (Click to View (Currently Only Available on Campus))
    URL: Volltext  (lizenzpflichtig)
    URL: Volltext  (Deutschlandweit zugänglich)
    URL: Volltext  (Deutschlandweit zugänglich)
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  • 2
    UID:
    gbv_1614720681
    Format: X, 447 Seiten , Zahlreiche Illustrationen , 240 mm x 165 mm
    ISBN: 9783486713480 , 3486713485
    Series Statement: Beiträge zur Militärgeschichte Band 73
    Content: Images of the enemy continue to play a significant role in the commemorative activities of many nations, and have often been cast in permanently offensive form in war memorials. For the first time, Loretana de Libero examines these "ardent passions" and their artistic expression in the memorial landscapes of Germany and its wartime enemies from the perspective of research on emotions and stereotypes
    Content: Images of the enemy continue to play a significant role in the commemorative activities of many nations, and have often been cast in permanently offensive form in war memorials. For the first time, Loretana de Libero examines these "ardent passions" and their artistic expression in the memorial landscapes of Germany and its wartime enemies from the perspective of research on emotions and stereotypes
    Note: Literaturverzeichnis: Seite 359 - 422 , I. "Aus unseren Knochen ein Rächer..." Kriegerische Drohungen gegen unsichtbare Feinde II. "...eine Welt von Feinden..." Der Feind als Bedrohung -- III. Triumph und Trophäen. Der Feind als überwundene Bedrohung.
    Additional Edition: ISBN 9783486854900
    Additional Edition: Erscheint auch als Online-Ausg. Libero, Loretana de, 1965 - Rache und Triumph München : Oldenbourg, 2014 ISBN 9783486854909
    Language: German
    Subjects: History
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    Keywords: Erster Weltkrieg ; Totengedächtnis ; Feindbild ; Rache ; Triumph ; Kriegerdenkmal ; Feindbild ; Geschichte 1918-1945 ; Historische Darstellung ; Historische Darstellung
    Author information: Libero, Loretana de 1965-
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Online Resource
    Online Resource
    Basel : Karger
    UID:
    b3kat_BV036069057
    Format: 1 Online-Ressource (VIII, 182 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318004632
    Series Statement: Chemical immunology Vol. 74
    Content: In a world full of pathogens the ability to detect an incipient infection and to respond rapidly and appropriately to it is a decisive part of our survival strategy. The innate immune system provides the first response to an infection by initiating an inflammatory response and the monocyte surface molecule CD14 is a key element in this response system. The initial chapters in this volume describe the structure and ligand interactions of this important receptor molecule which is involved both in inflammation and in some aspects of apoptosis. The very recent results which illuminate the probable signal transduction pathways are also described. Overactivation of the inflammatory response can lead to systemic inflammation and septic shock. Attempts to intervene clinically in this system have been disappointing, and the reasons for these failures are discussed in the context of the expression of TNF which is upregulated by CD14. A discussion of new data on the clinical course of shock and the currently emerging therapeutic strategies rounds off the book. The information compiled in this well-edited volume will be of use to everyone working on problems of inflammation - a topic where fundamental research and clinical medicine meet. Clinicians will find the current state of scientific knowledge on the inflammatory response as induced via CD14 presented in a readable form, while the clinical aspects discussed will be of particular interest to scientists and students who lack a medical background
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-6917-0
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Entzündung ; Antigen CD14 ; Antigen CD14 ; Immunreaktion ; Aufsatzsammlung ; Aufsatzsammlung
    Author information: Jack, Robert
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  • 4
    UID:
    b3kat_BV048222922
    Format: 1 Online-Ressource (148 pages)
    ISBN: 9783030386405
    Series Statement: Management for Professionals Ser
    Note: Description based on publisher supplied metadata and other sources , Intro -- Preface -- Contents -- Editors and Contributors -- 1 Strategic Management Control in Theory and Practice -- 1.1 Introduction -- References -- 2 Illustrating an Organisation's Strategy as a Map -- 2.1 Introduction -- 2.2 A Brief Look Back-Where Do Strategy Maps Come from? -- 2.3 IT as a Strategic Theme in the Strategy Map -- 2.4 Parks and Resorts Scandinavia's Strategy Map-An Example to Learn from -- 2.4.1 The Parks and Resorts Strategy Map -- 2.4.2 The Development of the Parks and Resorts Strategy Map -- 2.4.3 The Link Between the Parks and Resorts Strategy Map and Its Balanced Scorecard -- 2.5 Strategy Maps as a Form of Visual Narration -- 2.5.1 Economizing on the Means of Expression -- 2.5.2 The Story Behind Two Storytelling Maps -- 2.6 Conclusions -- References -- 3 Painting the Relevant Organisation -- 3.1 Introduction -- 3.2 Different Worldviews, Different Responses -- 3.3 Network Theory -- 3.4 What Is a Reasonable Perspective? -- 3.5 Value Systems -- 3.6 Imaginary Organisations -- 3.7 Ecology Perspectives -- 3.8 Powers that Control Boundary Limitations -- 3.9 Conclusions -- References -- 4 Planning for Control and Evaluation -- 4.1 Introduction -- 4.2 Control -- 4.3 Evaluation -- 4.4 Metrics, Decisions and Responsibility -- 4.4.1 Metrics -- 4.4.2 Decisions -- 4.4.3 Responsibility -- 4.5 The Strategic Dialogue -- 4.6 From Budgetary Control to the Management Control Package -- 4.6.1 The Management Control Package -- 4.6.2 The Control Mix -- 4.7 IT as Enabler -- 4.8 Conclusions -- References -- 5 Strategic Pricing: The Relationship Between Strategy, Price Models and Product Cost -- 5.1 Introduction -- 5.2 The Connections Between Business Strategy, Business Models and Price Models -- 5.3 Dimensions of Price Models -- 5.3.1 StayTheNight-A Price Model Example -- 5.4 Pricing, Customer Value and Cost Structure , 5.4.1 StayTheNight-An Illustrative Example -- 5.4.2 Use of the Value Creation Model -- 5.5 Conclusions -- References -- 6 Controlling and Being Controlled -- 6.1 Introduction -- 6.2 The Use of Control and the Voice of the Controlled -- 6.3 The Role of Accounting and the Risk of Overdose -- 6.4 Enabling Control with Dialogue -- 6.5 Prerequisites for Enabling Control with Dialogue -- 6.6 Conclusions -- References -- 7 The Controller's Role in Management Control Dialogues -- 7.1 Introduction -- 7.2 Management Control and Dialogue: What, Where and Between Whom? -- 7.3 The Role(s) of the Controller: Bookkeeper, Business Partner or Somewhere in Between? -- 7.4 The Controller and the Dialogue: Connecting Numbers, Operations and People -- 7.4.1 Alerting Dialogue: Defining the Magnitude of Problems -- 7.4.2 Problem-Solving Dialogue: Suggesting Solutions -- 7.4.3 Challenging Dialogue: Dispelling Myths and Highlighting the Unknown -- 7.4.4 Section Summary: Connecting Numbers, Operations and People -- 7.5 Some Keys to Management Control Dialogue: Physical Proximity and Subtle Communication -- 7.5.1 Physical Proximity Encourages Information Exchange -- 7.5.2 How Information Is Communicated Matters -- 7.6 Conclusions -- References -- 8 Management Control as Strategic Dialogue-A Memoir -- 8.1 What a Half-Century in Management Control Can Teach -- 8.2 A Perspective from the 1960s -- 8.2.1 Control Was New Yet Mature -- 8.2.2 Decentralization and Informed "Co-workers" -- 8.2.3 A Focus on Decisions -- 8.2.4 "Multiobjective Budgetary Planning" -- 8.3 Determinants for Control 50 Years Later -- 8.3.1 Disappointments and Renewed Efforts: Fast-Forward to the 1990s -- 8.3.2 Did Its Time Arrive? -- 8.3.3 Public and Private Dissolve -- 8.3.4 Controllership for the 21st Century -- 8.4 Interpreting, Preaching, and Practicing -- References -- 9 Conclusions , 9.1 Strategic Management Control-Successful Strategies Based on Dialogue and Collaboration -- 9.2 Summarising Messages and Themes -- Index
    Additional Edition: Erscheint auch als Druck-Ausgabe Nilsson, Fredrik Strategic Management Control Cham : Springer International Publishing AG,c2020 ISBN 9783030386399
    Language: English
    Subjects: Economics
    RVK:
    Keywords: Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 5
    Online Resource
    Online Resource
    Cham : Springer International Publishing AG
    UID:
    b3kat_BV048224258
    Format: 1 Online-Ressource (249 Seiten)
    ISBN: 9783030497095
    Series Statement: Tourism on the Verge Ser
    Note: Description based on publisher supplied metadata and other sources , Intro -- Foreword -- Contents -- About the Authors -- Introduction to Eye Tracking in Tourism -- References -- Part I: Eye Tracking Methods, Concepts and Applications -- A Review of Eye-Tracking Methods in Tourism Research -- 1 Introduction -- 2 Theoretical Basis for Eye-Tracking -- 3 Data Collection and Analysis Procedures -- 3.1 Eye-Tracking Technologies and Devices -- 3.2 Data Collection Procedure -- 3.3 Data Analysis Procedure -- 3.4 Advantages and Disadvantages of Eye-Tracking Methods -- 4 Eye-Tracking Applications in Tourism Research -- 4.1 Tourism Research Using Eye-Tracking -- 4.2 Future Research Directions -- 4.3 Eye-Tracking for Tourism Marketers -- References -- Best Practices for Eye-Tracking Studies: Dos and Don'ts -- 1 Introduction -- 2 Review of the Eye-Tracking Literature -- 2.1 Eye-Tracking in Advertising Studies -- 2.2 Eye-Tracking in Tourism Studies -- 2.3 Stimuli and Research Methods -- 3 Dos and Don'ts for Eye-Tracking -- 3.1 Preparation and Set-Up -- 3.2 Participant Interaction -- 3.3 Software -- 3.4 Researcher Behaviour -- 4 Tobii Pro Experience Report -- 4.1 Advantages -- 4.2 Disadvantages -- 5 Conclusions and Implications -- References -- Eye Tracking: Evaluation, Potential and Limitations of Field Applications -- 1 Introduction to the Rationale for the Use of Eye Tracking in Tourism -- 1.1 The Evaluation of the Effectiveness of Print and Online Materials -- 1.2 The Usability Studies of Websites -- 1.3 Understanding Consumer Behaviour -- 2 The Potential of Eye Tracking in Tourism and Application Examples -- 3 Combining Eye Tracking with Other Neuromarketing Tools -- 4 The Advantages, Potential, Limitations and Drawbacks of Eye Tracking -- 4.1 The Advantages and the Potential -- 4.2 The Limitations and Drawbacks -- 5 Conclusion -- References -- Knowledge Co-creation Through Eye-Tracking in Tourism -- 1 Introduction , 2 Eye-Tracking Research -- 3 Eye-Tracking and Tourism -- 4 The Model -- 5 Concluding Remarks -- References -- Part II: Eye Tracking Research and Case Studies -- The Relevance of Eye-Tracking to Understand Users' Practices and Content Interpretation in Tourism-Related Online Navigation -- 1 Introduction -- 2 Related Works -- 2.1 Eye-Tracking Technique and Tourism -- 2.2 Eye-Tracking Technique and Users' Practices -- 3 Research Design -- 3.1 Selection of Stimuli -- 3.2 Setting of the Experiment -- 4 Results -- 4.1 Self-Declared Willingness to Visit Ticino -- 4.2 Correlation Between Eye-Tracking (ET) Outcome and Self-Declaration of Main Topic, Subtopic, and Main Sentiment Expressed f... -- 5 Conclusions -- References -- Areas of Interest on Destination Websites: A Generation Y's Perspective -- 1 Introduction -- 2 Theoretical Background -- 2.1 Consumer Behaviour -- 2.2 Sensory Marketing -- 2.3 Perception of Quality -- 2.4 Generation Y -- 3 Methodology -- 3.1 Experimental Research Design -- 3.2 Key Findings -- 3.2.1 Pictures Scoring the Highest Fixation Count -- 3.2.2 Pictures of Famous People Do Not Receive the Highest Attention -- 3.2.3 Social Media Is Not Perceived as an Important Element Within the First Impression -- 3.2.4 Destination Websites Are Rather Seen as a Platform for Information than for Booking Intentions -- 3.2.5 During the Phase of First Impression, Website Elements Embedded in Lower Parts of a Website Are Not Perceived -- 3.2.6 Differences Exist Between Men and Women Within the First Impressions -- 4 Limitations and Conclusions -- References -- Measurement of Visual Attention to Advertising Using Eye-Tracking Techniques -- 1 Introduction -- 2 Real-Time Measurement of Visual Attention Using Eye-Tracking -- 3 Method -- 3.1 Experiment 1: The Relationship Between Attention to Tourism Packages and Intention to Purchase , 3.2 Experiment 2: The Effect on Visual Attention of Manipulating Textual Information -- 3.3 Experiment 3: The Effectiveness of Tourism Print Advertising -- 3.4 Experiment 4: The Effectiveness of a Promotion on a Hotel Website -- 4 Conclusion -- References -- User Experience Improvement for Online Travel Agencies Through Eye-Tracking: The Onlineweg.de Case Study -- 1 Introduction -- 2 The Market Environment of the Multichannel E-Commerce Company Onlineweg.de -- 2.1 The Growth of E-Tourism in Germany -- 2.2 Dynamic Competition Among Online Travel Agencies -- 2.3 Highlighting a Key Target Group for Onlineweg.de -- 3 Literature Review -- 4 Methodological Approach -- 4.1 Selecting the Test Users -- 4.2 Recruiting the Test Users -- 4.3 Data Collection -- 5 The Use Cases Studied -- 5.1 Characterization of Task (1) -- 5.2 Characterization of Task (2) -- 6 Results of the Eye-Tracking Analysis -- 6.1 Task (1) -- 6.2 Task (2) -- 7 General Assessment of the Quality of Onlineweg.de by the Test Users -- 8 Recommendations for Improvements -- 9 Conclusion -- References -- Areas of Interest for a CSR Certificate on Touristic Websites: An Eye-Tracking Experiment Using the Example of TourCert -- 1 Introduction -- 2 Certifications and Certificates in Tourism -- 3 Basics About Eye-Tracking -- 4 Set-Up, Conduction and Result of the Experiment -- 5 The Experiment -- 6 Results -- 7 Analysis of Results -- 8 Conclusion -- Davenport -- References -- Acquiring Sustainability Information in Holiday Travel -- 1 Introduction: Objective and Framework -- 2 Study Design and Data Collection -- 2.1 Study Design -- 2.1.1 Set 1 -- 2.1.2 Set 2 -- 2.1.3 Set 3 -- 2.1.4 Pre- and Post-experimental Questionnaires -- 2.2 Data Collection and Data Analysis -- 2.2.1 Data Collection -- 2.2.2 Data Analysis -- 2.3 Respondent Profiles -- 2.3.1 Structural Data , 2.3.2 Involvement with Holiday Travel and Sustainable Products -- 2.3.3 Attitudes Towards Sustainable Holiday Trips -- 3 Results -- 3.1 Overview of Hypotheses -- 3.2 H1 (Zero Case) -- 3.3 H2 (Attitude) -- 3.3.1 Fixation Counts -- 3.3.2 Fixation Duration -- 3.4 H3 (Availability) -- 3.4.1 Fixation Counts -- 3.4.2 Fixation Durations -- 3.5 H4 (Instruction) -- 3.5.1 Fixation Counts -- 3.5.2 Fixation Duration -- 3.6 H5 (Instruction-Attitude) -- 3.6.1 Fixation Counts -- 3.6.2 Fixation Duration -- 4 Discussion -- 5 Conclusion -- References -- The Museum Learning Experience Through the Visitors' Eyes: An Eye Tracking Exploration of the Physical Context -- 1 Introduction -- 2 Literature Review -- 2.1 The Importance of Visual Attention -- 2.2 Visitors' Gazes in the Museum Context -- 2.3 Contextual Model of Learning -- 3 Methodology -- 3.1 Sampling and Data Collection -- 3.2 Data Analysis -- 4 Results -- 4.1 Descriptive Statistics -- 4.2 Main Analysis -- 5 Discussion -- 6 Conclusion -- 6.1 Theoretical and Practical Implications -- 6.2 Directions for Future Research -- References -- Using Mobile Eye-Tracking to Inform the Development of Nature Tourism Destinations in Iceland -- 1 Introduction -- 1.1 Structure of Chapter -- 1.2 Mobile Eye-Tracking -- 1.3 Eye-Tracking in Ecotourism -- 1.4 Effective Strategies for Managing Tourist Behavior -- 1.5 Selection of Study Area -- 1.5.1 Areas of Interest Within Iceland -- 1.5.2 Þingvellir -- 1.5.3 Sólheimajökull -- 2 Methodology -- 2.1 Participant Recruitment -- 2.2 Mobile Eye-Tracking Trial -- 2.3 Post-survey -- 2.4 Observational Data Collection -- 3 Data Analysis -- 3.1 Footpath Analysis -- 3.2 Eye-Tracking Analysis -- 3.3 Nonparticipant Observational Data -- 4 Results -- 4.1 Identified Learning and Management Issues in Ecotourism Destinations -- 4.2 Effective Strategies for Managing Tourist Behavior , 5 Discussion and Conclusions -- 5.1 LA-MET and Mixed Methods -- 5.2 Study Limitations -- 5.3 MET as an Effective Tool in Managing Nature Tourism -- References -- Viewing Behaviour and Task Performance on Austrian Destination Websites: Comparing Generation Y and the Baby Boomers -- 1 Introduction -- 2 Theoretical Background -- 2.1 Fundamentals of Web Page Viewing Behaviour -- 2.2 Eye Tracking as a Usability Evaluation Method -- 2.3 Literature Review of Generational and Age-Related Differences -- 3 Experimental Research Design -- 3.1 Definition of the Sample -- 3.2 Method of Data Collection -- 4 Research Results -- 4.1 Differences and Similarities in Viewing Behaviour -- 4.2 Differences and Similarities in Perceived Usability and Task Performance -- 5 Discussion -- 6 Conclusion -- 6.1 Implications and Recommendations -- 6.2 Limitations and Further Research -- References
    Additional Edition: Erscheint auch als Druck-Ausgabe Rainoldi, Mattia Eye Tracking in Tourism Cham : Springer International Publishing AG,c2020 ISBN 9783030497088
    Language: English
    Subjects: Economics , General works
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    Keywords: Web-Seite ; Visuelle Aufmerksamkeit ; Blickverhalten ; Tourismusforschung ; Augenfolgebewegung ; Aufsatzsammlung ; Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 6
    Online Resource
    Online Resource
    Singapore : Springer Nature Singapore | Singapore : Springer
    UID:
    b3kat_BV048982557
    Format: 1 Online-Ressource (XV, 174 p. 110 illus., 81 illus. in color)
    Edition: 1st ed. 2023
    ISBN: 9789811969058
    Series Statement: New Frontiers in Regional Science: Asian Perspectives 65
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1969-04-1
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1969-06-5
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-981-1969-07-2
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 7
    Online Resource
    Online Resource
    London : Palgrave Macmillan UK
    UID:
    b3kat_BV047942831
    Format: 1 Online-Ressource (XVI, 698 Seiten)
    Edition: Third Edition
    ISBN: 9781403946089
    Content: The successful first edition provided an introduction to the valuation and risk management of modern financial instruments, formulated in a precise mathematical expression and comprehensively covering all relevant topics using consistent and exact notation. In this edition, Deutsch continues with this philosophy covering new and more advanced topics including risk adjusted performance and portfolio optimization. This edition also includes a CD-ROM in the form of Excel workbooks giving detailed models of the concepts discussed in the book
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9781349515424
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
    URL: Volltext  (Deutschlandweit zugänglich)
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  • 8
    Online Resource
    Online Resource
    Cambridge : Royal Society of Chemistry | [distributor] RSC Distribution Services]
    UID:
    b3kat_BV037195342
    Format: 1 Online-Ressource (316 p.) , 118 col.ill
    ISBN: 1847555292 , 9781847555298
    Series Statement: RSC Biomolecular sciences
    Note: This product is not available separately, it is only sold as part of a set. There are 750 products in the set and these are all sold as one entity, Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered. Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability. The biology of quadruplexes and G-rich genomic regions and G-quartets in supramolecular chemistry and nanoscience are also considered. Surveying the current state of knowledge, and with contributions from leading experts, this is the first comprehensive review of this rapidly growing area. Quadruplex Nucleic Acids is ideal for researchers interested in areas related to chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology
    Language: English
    Subjects: Chemistry/Pharmacy , Biology
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    Keywords: Quadruplex-DNS
    URL: Volltext  (Deutschlandweit zugänglich)
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  • 9
    UID:
    b3kat_BV037195499
    Format: 1 Online-Ressource (380 p.) , 101 b&w, ill
    ISBN: 1847558763 , 9781847558763
    Series Statement: RSC Biomolecular sciences v. 15
    Note: Provides a perspective on nucleic acid-metal ion interactions with an emphasis on experimental biophysical studies which will prove indispensable to biophysicists and molecular biologists, Natural biochemical processes are routinely being discovered in living cells that involve RNA. Some of these processes, such as RNA interference, are now being exploited for biotechnology and medicinal applications. DNA has also proven in recent years to be more than a passive storehouse of information. For example, non-B-form DNA structures formed by G-rich DNA have been shown to participate in the regulation of gene expression, a discovery that presents new possibilities for drug targets in the genome. The current quest to understand how nucleic acid functions at the most fundamental level requires that we have a detailed understanding of nucleic acid-metal ion interactions. Because RNA and DNA are polyanions the structure and biological function of these biopolymers depends strongly on their association with metal ions. While this intimate connection between metal ions and nucleic function has been appreciated for decades, the noncovalent and dynamic nature of these interactions has continually presented challenges to the development of accurate and quantitative descriptions. Over the past few years the development of solution state spectroscopic techniques and the achievement of high resolution X-ray crystal structures have provided tremendous insights into the nature of nucleic acid-metal ion interactions, including direct evidence for their importance in determining nucleic acid structure, from the dictation of folding pathways followed by large RNA molecules to the subtle modulation of DNA groove widths. This new book provides a comprehensive review of the experimental studies that define our current understanding of nucleic acid-metal ion interactions with a particular ++ , emphasis being placed on experimental biophysical studies. However, the book is not merely a current review of the literature, as original material and fresh perspectives on published results are also presented. Particularly noteworthy topics include: -The chapter by Williams and fellow workers which reviews information provided by x-ray crystal structures and discusses what this information has revealed about the unique nature of Mg2+ interactions with RNA phosphate groups. The authors provide fresh insights, based upon structural comparisons, for how these interactions govern the local folding pathways of RNA. By dedicating separate chapters to the participation of metal ions in the kinetics and thermodynamics of RNA folding, this volume provides a more in depth treatise of both areas than is typically possible for reviews in which these two related, but distinct, topics are combined -Polyelectrolyte models of nucleic acids have proven to be extremely valuable for understanding the sequestering counterions in a so-called diffuse cloud around polymeric DNA. J. Michael Schurr provides a comprehensive review of polyanion models. of nucleic acid-metal ion interactions. Despite the success of polyelectrolyte models in describing some physical properties of nucleic acids, this topic is not always sufficiently understood by many researchers to make use of these models and this chapter serves as a valuable and up to date introduction to this topic. -The chapter by Pizarro and Sadler on metal ion-nucleic acid interactions in disease and medicine is complemented by a chapter by Lippert on coordinative bond formation between metal ions and nucleic acid bases. Together, these two chapters provide an overview of transition metal ion interactions with nucleic acids that illustrates the promise and peril that is associated with direct metal ion coordination to nucleic acid b++e , s in living cells. The book is sufficiently detailed to serve as a reference source for researchers active in the field of nucleic acids biophysics and molecular biology. In addition, chapter authors have added introductory material and enough background material in each chapter so that the book can also can serve as an entry point for students and researchers that have not previously worked in the field which will make the book of lasting value and more accessible by a wider audience
    Language: English
    Subjects: Chemistry/Pharmacy
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    Keywords: Nucleinsäuren ; Metallion
    URL: Volltext  (Deutschlandweit zugänglich)
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  • 10
    Book
    Book
    Berkeley, Calif. [u.a.] : Univ. of California Press
    UID:
    b3kat_BV010434958
    Format: XVII, 297 S. , Ill., Notenbeisp. , 24 cm
    Edition: 1. paperback print.
    ISBN: 0520088204
    Note: Prospects: postmodernism and musicology -- From the other to the abject: music as cultural trope -- Music and representation: in the beginning with Haydn's Creation -- Musical narratology: a theoretical outline -- Felix culpa: Mendelssohn, Goethe, and the social force of musical expression -- The Lied as cultural practice: tutelage, gender, and desire in Mendelssohn's Goethe songs -- Cultural politics and musical form: the case of Charles Ives -- Consuming the exotic: Ravel's Daphnis and Chloe -- Autonomy, Elvis, Cinders, fingering Bach -- Mendelssohn: three Goethe songs.
    Language: English
    Subjects: Musicology
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    Keywords: Postmoderne ; Klassische Musik ; Musikästhetik ; Postmoderne
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