Kooperativer Bibliotheksverbund

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Format: 1 online resource (341 pages)

Edition: 1st ed.

ISBN: 9783030050757

Series Statement: Demographic Research Monographs

Note: Intro -- Preface -- Contents -- Chapter 1: Introduction -- 1.1 The Need for Accurate Mortality Forecasts Is Greater Than Ever Before -- 1.2 Determinants and Dynamics of Life Expectancy - Pensions Are Upping the Ante for the Challenge Facing the Art of Projecting... -- 1.3 Cause of Death Forecasts -- 1.4 Period and Cohort Perspectives -- 1.5 Joint Forecasting of Mortality in Similar Populations -- 1.6 From Scenarios to Stochastic Modelling -- 1.7 How Conditions in Early Life Affect Mortality in Later Life -- 1.8 The Increasing Gap in Life Expectancy with Respect to Position in the Income Distribution -- References -- Part I: Current Practice -- Chapter 2: Life Expectancy Is Taking Center Place in Modern National Pension Schemes - A New Challenge for the Art of Projecti... -- 2.1 Introduction -- 2.2 Basic Pension Economics - The Role of Mortality -- 2.3 NDC and FDC Schemes - And Life Expectancy -- 2.4 Itś More Important Than Ever to Project Life Expectancy Accurately -- 2.5 Final Comments -- References -- Chapter 3: Experiences from Forecasting Mortality in Finland -- 3.1 Modeen and Törnqvist -- 3.2 Official Forecasts -- 3.3 Predictive Distribution of Mortality -- 3.4 Applications -- References -- Chapter 4: Mortality Projections in Norway -- 4.1 A Brief Description of the Norwegian Population Projection Model -- 4.2 A Short History of Mortality Projections in Norway -- 4.3 Current Methodology of Mortality Projections -- 4.3.1 Target Life Expectancies -- 4.3.2 Difference in Target e0 for Males and Females -- 4.3.3 Life Expectancies in the First Projection Year -- 4.3.4 Path of e0 from the Initial Until the Target Year -- 4.3.5 Slope of e0 in the Target Year -- 4.3.6 Alternative Mortality Assumptions -- 4.3.7 Age Groups -- 4.3.8 Cohort Mortality -- 4.4 Age-Specific Trends in Mortality Rates -- 4.5 Projections of Age-Specific Mortality Rates. , 4.6 Projection Results -- References -- Chapter 5: Mortality Assumptions for Sweden. The 2000-2050 Population Projection -- 5.1 Mortality Projection in Sweden -- 5.2 Sharply Lower Mortality in 1950-1999 -- 5.3 Reasons for the Decline in Mortality in 1980-1999 -- 5.4 Higher Average Life Expectancy in 1950-1999 -- 5.5 Future Mortality -- 5.6 Assumptions Used in the Forecast for the Immediate Future -- 5.7 Assumptions Used in the Forecast for the Longer Term -- 5.8 Mortality Trends over the Period 1950-2050 -- 5.9 Higher Average Life Expectancy -- 5.10 Assumptions Regarding Mortality Trends in Some Countries -- 5.11 Alternative Assumptions -- Chapter 6: Forecasting Life Expectancy: The SCOPE Approach -- References -- Chapter 7: Mortality Forecasts. Comments on How to Improve Existing Models - An Epidemiologistś Perspective -- 7.1 Are the Lifespans of Relatives Correlated? -- 7.2 The Relative Effects of Genetic and Environmental Factors on Lifespan -- 7.3 Prediction of Mortality -- 7.4 Conclusion -- References -- Chapter 8: The Need for Looking Far Back in Time When Predicting Future Mortality Trends -- References -- Part II: Probabilistic Models -- Chapter 9: Erroneous Population Forecasts -- 9.1 Forecast Accuracy -- 9.2 Why Population Forecasts Are Inaccurate -- 9.3 Empirical Evidence from Historical Forecasts -- 9.3.1 Forecasts Are More Accurate for Short Than for Long Forecast Durations -- 9.3.2 Forecasts Are More Accurate for Large Than for Small Populations -- 9.3.3 Forecasts of the Old and the Young Tend to Be Less Accurate Than Those of Intermediate Age Groups -- 9.3.4 Accuracy Differs Between Components and Regions -- 9.4 The Expected Accuracy of Current Forecasts -- 9.5 Probabilistic Forecasts: An Alternative to Forecast Variants -- 9.6 Challenges in Probabilistic Population Forecasting -- References. , Chapter 10: Remarks on the Use of Probabilities in Demography and Forecasting -- 10.1 Introduction -- 10.2 Binomial and Poisson Models -- 10.3 Random Rates -- 10.4 Handling of Trends -- 10.5 On Judgment and Subjectivity in Statistical Modeling -- 10.6 On the Interpretation of Probabilities -- 10.7 Eliciting Expert Views on Uncertainty -- References -- Chapter 11: An Expert Knowledge Approach to Stochastic Mortality Forecasting in the Netherlands -- 11.1 Introduction -- 11.2 Stochastic Population Forecasts: Methodology -- 11.2.1 An Analysis of Errors of Past Forecasts -- 11.2.2 Model-Based Estimate of Forecast Errors -- 11.2.3 Expert Judgement -- 11.3 Using Expert Knowledge -- 11.4 Expert Knowledge in the Dutch Stochastic Mortality Forecasts -- 11.5 Conclusions -- Appendix: An Explanatory Model for Dutch Mortality -- References -- Chapter 12: Stochastic Forecasts of Mortality, Population and Pension Systems -- 12.1 Introduction -- 12.2 Stochastic Forecasts -- 12.3 Mortality Forecasts -- 12.4 From Population to Pension Systems and Policy -- References -- Part III: The Linear Rise in Life Expectancy: History and Prospects -- Chapter 13: The Linear Rise in the Number of Our Days -- 13.1 Better Forecasts -- 13.2 Continuing Belief in Looming Limits -- References -- Chapter 14: Mortality Forecasts and Linear Life Expectancy Trends -- 14.1 Introduction -- 14.2 Linear Change in Life Expectancy over Long Historical Periods -- 14.3 What Is Fundamental, Age at Death or Risk of Death? -- 14.4 Using These Findings to Improve Mortality Forecasts -- 14.5 Considering National Mortality Change in an International Context -- 14.6 Extensions -- 14.6.1 Heterogeneous Targets -- 14.6.2 Heterogeneous Rates of Convergence -- 14.7 Forecasting Mortality -- References -- Chapter 15: Forecasting Life Expectancy: A Statistical Look at Model Choice and Use of Auxiliary Series. , 15.1 Why Forecast Life Expectancy? -- 15.2 Changes in Life Expectancy in 19 Industrialized Countries in 1950-2000 -- 15.3 Conditions on the Usefulness of an Auxiliary Series -- 15.4 Model Choice -- 15.5 Concluding Remarks -- References -- Chapter 16: Life Expectancy Convergence Among Nations Since 1820: Separating the Effects of Technology and Income -- 16.1 Limits and Convergence in Life Expectancy -- 16.2 The Classic Article: Preston (1975) -- 16.3 Extending the Analysis -- 16.4 New Data -- 16.5 National Effects: A Shopping Analogy -- 16.6 Multilevel Models -- 16.7 Model Results -- 16.8 National Patterns -- 16.9 Convergence -- 16.10 Conclusion -- References -- Chapter 17: Linear Increase in Life Expectancy: Past and Present -- 17.1 Descriptive Overview -- 17.2 Causes -- 17.3 Summary and Discussion -- References -- Part IV: Causes of Death -- Chapter 18: How Useful Are the Causes of Death When Extrapolating Mortality Trends. An Update -- 18.1 Extrapolation of Mortality by Cause Risks Absurdity -- 18.2 Would More Sophisticated Methods Be Any Better? -- 18.2.1 A Better Adjustment of Chronological Series of Rates by Age -- 18.2.2 ``Age-Period ́́Adjustment (Lee-Carter Model) -- 18.2.3 ``Age-Period-Cohort ́́Adjustment (APC Model) -- 18.3 The Models Put to the Proof -- 18.4 Conclusion -- References -- Chapter 19: Forecasting Life Expectancy and Mortality in Sweden - Some Comments on Methodological Problems and Potential Appro... -- 19.1 Introduction -- 19.2 The Relationships Between Incidence, Prevalence and Mortality -- 19.3 Extrapolating Mortality Trends or Predicting Disease-Specific Causes of Death -- 19.4 Predicting Mortality Based on Potential Elimination of Causes of Death -- 19.5 Predicting Mortality Based on Development of Risk Factors -- 19.6 Methodological Problems in Predicting Mortality Based on Risk Factor Predictions. , 19.7 Future Mortality and Longevity -- 19.8 Implications for the Future -- References -- Chapter 20: How Analysis of Mortality by Cause of Death Is Currently Influencing UK Forecasts -- 20.1 Mortality Improvement in the UK -- 20.2 Current Methodologies and Research in the UK -- 20.3 Understanding the ``UK Cohort Effect ́́-- 20.4 Modelling Mortality by Cause of Death -- 20.5 Implications and Conclusions -- References -- Part V: Cohort Factors: How Conditions in Early Life Influence Mortality Later in Life -- Chapter 21: A Life Course Perspective to the Modern Secular Mortality Decline and Socioeconomic Differences in Morbidity and M... -- 21.1 The Secular Mortality Decline: Early Life and Cohort Explanations and Their Indicators -- 21.2 Historical Trends and Socioeconomic Mortality Differences in a Life Course and Cohort Perspective -- 21.3 Cohort Effects on Mortality and Mortality Predictions: Indicators and Models -- References -- Chapter 22: Early Life Events and Later Life Health: Twin and Famine Studies -- 22.1 Introduction -- 22.2 Famine Early in Life and Later Life Health -- 22.3 Later Life Health for Twins -- 22.4 Twins and Genetic Confounding -- 22.5 Overview -- References -- Chapter 23: The Month of Birth: Evidence for Declining but Persistent Cohort Effects in Lifespan -- 23.1 Introduction -- 23.2 Data -- 23.3 Methods -- 23.4 Results -- 23.4.1 Differences in Lifespan in the United States, Austria, Denmark and Australia -- 23.4.2 Changes in the Month-of-Birth Pattern over Cohorts in Denmark -- 23.4.3 Changes in the 20-Year Survival Probability by Quarter of Birth in the United States -- 23.5 Discussion -- 23.6 Conclusion -- References -- Chapter 24: Early-Life Conditions and Old-Age Mortality in a Comparative Perspective: Nineteenth Century Sweden and Belgium -- 24.1 Introduction -- 24.2 Models -- 24.3 Data for Scania -- 24.4 Data for Sart. , 24.5 Results.

Additional Edition: Print version: Bengtsson, Tommy Old and New Perspectives on Mortality Forecasting Cham : Springer International Publishing AG,c2019 ISBN 9783030050740

Language: English

Subjects: Medicine , Sociology

Keywords: Electronic books. ; Aufsatzsammlung ; Electronic books

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Format: 1 Online-Ressource (393 Seiten) : , Illustrationen, Karten.

ISBN: 978-3-8452-8600-6

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8487-4328-5

Language: English

Subjects: Economics , Political Science , Law , Medicine

Keywords: Modellprojekt Health Promoting Hospitals ; Ebola-Virus ; Epidemie ; Gesundheitspolitik ; Nichtstaatliche Organisation ; Ebola-Virus ; Epidemie ; Gesundheitspolitik ; Recht auf Gesundheit ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung

DOI: 10.5771/9783845286006

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Author information: Villarreal, Pedro A. 1984-

Author information: Vierck, Leonie 1982-

Author information: Weilert, A. Katarina

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Format: xvi, 389 Seiten : , Illustrationen.

ISBN: 978-0-520-28234-6

Series Statement: Weimar and now: German cultural criticism 50

Additional Edition: Erscheint auch als Online-Ausgabe ISBN 978-0-520-95796-1

Language: English

Subjects: History , Musicology , Art History

Keywords: Künste ; Kulturpolitik ; Drittes Reich ; Drittes Reich ; Kulturgeschichtsschreibung

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029046038&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

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Author information: Potter, Pamela Maxine

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Format: XVII, 303 p. 124 illus., 97 illus. in color. , online resource.

ISBN: 9783030031497

Content: This Open access book offers updated and revised information on vessel health and preservation (VHP), a model concept first published in poster form in 2008 and in JVA in 2012, which has received a great deal of attention, especially in the US, UK and Australia. The book presents a model and a new way of thinking applied to vascular access and administration of intravenous treatment, and shows how establishing and maintaining a route of access to the bloodstream is essential for patients in acute care today. Until now, little thought has been given to an intentional process to guide selection, insertion and management of vascular access devices (VADs) and by default actions are based on crisis management when a quickly selected VAD fails. The book details how VHP establishes a framework or pathway model for each step of the patient experience, intentionally guiding, improving and eliminating risk when possible. The evidence points to the fact that reducing fragmentation, establishing a pathway, and teaching the process to all stakeholders reduces complications with intravenous therapy, improves efficiency and diminishes cost. As such this book appeals to bedside nurses, physicians and other health professionals.

Note: Preface. About the concept of VHP, beginnings, process and ideal -- Section 1. Right Assessment and Right Vein -- Chapter 1. Catheter and vein selection with avoidance of joints and danger zones -- Chapter 2. Ultrasonic assessment and placement of right device -- Section 2. Right Training -- Chapter 3. Training process, competencies, preparation for PIV, PICC, CVC insertions -- Section 3. Right Insertion -- Chapter 4. Catheter size, type, number of lumen for patient and treatment -- Chapter 5. Placement with no more than 2 attempts -- Chapter 6. Infection Prevention principles with Kits for insertion and compliance with sterile procedure (bundles, checklist, CHG, etc) -- Chapter 7. Tip positioning -- Chapter 8. Securement -- Section 4. Pediatric Vessel Health -- Chapter 9. Differences between paediatrics and adults for vein assessment -- Chapter 10. Right Site selection -- Chapter 11. Right Device assessment (type, size, no. of lumens) -- Chapter 12. Right Technology assessment -- Chapter 13. Why is VHP important in paediatrics? -- Chapter 14. Troubleshooting in paediatrics -- Section 5. Right Supplies and Technology -- Chapter 15. Ultrasound -- Chapter 16. Insertion kits for USGPIV, PICC, Midline, CVC -- Chapter 17. Antimicrobial dressings -- Chapter 18. Needleless connector issues -- Section 6. Right Care and Assessment -- Chapter 19. Daily or twice daily assessment for catheter function, dressing adherence and necessity of device -- Chapter 20. Hub disinfection issues and compliance measures -- Chapter 21. Flushing with proper techniques -- Section 7. Right Evaluation -- Chapter 22. How to evaluate a VHP program initiative -- Chapter 23. Staff education and satisfaction -- Chapter 24. Patient satisfaction -- Chapter 25. Pathway effectiveness and outcome measures.

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Additional Edition: Printed edition: ISBN 9783030031480

Additional Edition: Printed edition: ISBN 9783030031503

Language: English

Subjects: Medicine

Keywords: Electronic books. ; Aufsatzsammlung

DOI: 10.1007/978-3-030-03149-7

URL: https://doi.org/10.1007/978-3-030-03149-7

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Format: 1 Online-Ressource (xv, 216 Seiten)

ISBN: 9783030031435

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-03142-8

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-03144-2

Language: English

Subjects: Medicine

Keywords: Medizin ; Sepsis ; Intensivpflege ; Notfallmedizin ; Chirurgie ; Aufsatzsammlung ; Electronic books

DOI: 10.1007/978-3-030-03143-5

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Author information: Schultz, Marcus J.

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Format: 1 online resource (411 pages)

Edition: 1st ed.

ISBN: 9783030166380

Note: Intro -- Foreword 1 -- In Memoriam Dr. Gerhard Zinser -- Foreword 2 -- Memories -- Preface -- Acknowledgment -- Contents -- Contributors -- Part I: Breaking the Diffraction Barrier in Fluorescence Microscopy -- 1: High-Resolution 3D Light Microscopy with STED and RESOLFT -- 1.1 Breaking the Diffraction Barrier in the Far-field Fluorescence Microscope -- 1.2 Recent Developments: Nanoscopy at the MINimum -- References -- Part II: Retinal Imaging and Image Guided Retina Treatment -- 2: Scanning Laser Ophthalmoscopy (SLO) -- 2.1 Introduction and Technology -- 2.1.1 History -- 2.1.2 Modern Confocal SLO -- 2.1.3 SLO Core Components -- 2.1.3.1 Laser Source -- 2.1.3.2 Scan Unit -- 2.1.3.3 Beam Splitter -- 2.1.3.4 Imaging Optics -- 2.1.3.5 Detectors -- 2.1.4 Resolution of the SLO -- 2.1.4.1 Limitations and Numerical Aperture (NA) of the Eye -- 2.1.4.2 Fraunhofer Diffraction at a Circular Aperture -- 2.1.4.3 Beam Waist for Propagating Gaussian Beam -- 2.1.4.4 Resolution Improvement Due to Confocal Detection -- 2.1.5 Example for High Resolution SLO Image -- 2.2 Laser Scanning Tomography -- 2.2.1 HRTII/HRT3 Acquisition Work Flow -- 2.2.2 HRTII/HRT3 Data Processing -- 2.2.3 Contour Line, Reference Plane and Stereometric Parameters -- 2.2.4 Analysis of HRT Optic Nerve Head (ONH) Data -- 2.2.4.1 ONH Classification Based on Moorfields Regression Analysis -- 2.2.4.2 Follow-Up and Progression Analysis -- 2.2.5 Summary SLT for Glaucoma Diagnostics -- 2.3 Widefield Indocyanine Green Angiography (ICGA) -- 2.4 Quantitative Autofluorescence of the Retina -- 2.4.1 Origin and Spectral Characteristics of Fundus Auto-Fluorescence (AF) -- 2.4.2 Quantitative Auto-Fluorescence (AF) Imaging -- 2.4.3 Research Studies -- 2.5 Summary and Conclusion -- References -- 3: Optical Coherence Tomography (OCT): Principle and Technical Realization. , 3.1 Introduction -- 3.2 Technique and Theory of OCT -- 3.2.1 Principle Idea of OCT -- 3.2.2 Technical realizations of OCT -- 3.2.3 Signal formation in OCT -- 3.2.4 Lateral and Axial Resolution and Image Dimensions -- 3.2.5 Sensitivity and Roll-Off -- 3.2.6 Signal Averaging and Speckle -- 3.3 SPECTRALIS OCT -- 3.4 Additional OCT Contrast Mechanisms and New Technologies -- 3.4.1 OCT Angiography (OCTA) -- 3.4.2 Quantitative Measurement of Retinal Blood Flow -- 3.4.3 OCT with Visible Light (Vis-OCT) -- 3.4.3.1 Resolution -- 3.4.3.2 Spectral Imaging, Oximetry -- 3.4.4 OCT Elastography (OCE) -- 3.4.5 Polarization Sensitive OCT (PS-OCT) -- 3.4.6 Adaptive Optics OCT (AO-OCT) -- 3.4.7 High Speed OCT -- 3.4.7.1 Fourier Domain Mode Locked (FDML) Lasers with MHz Sweep Rate -- 3.4.7.2 Parallelization of OCT Data Acquisition -- 3.5 Summary and Conclusion -- References -- 4: Ophthalmic Diagnostic Imaging: Retina -- 4.1 Introduction -- 4.2 Application of OCT in Retinal Diagnostics -- 4.2.1 Age-Related Macular Degeneration -- 4.2.2 Diabetic Retinopathy and Macular Edema -- 4.2.3 Retinal Vascular Occlusions and Other Vascular Conditions -- 4.2.4 Central Serous Chorioretinopathy and Related Diseases -- 4.2.5 Pathologic Myopia -- 4.2.6 Inherited Retinal Diseases and Other Macular Conditions -- 4.2.7 Intraocular Tumors -- 4.2.8 Inflammatory Diseases, Intermediate and Posterior Uveitis -- 4.2.9 Vitreoretinal Interface -- 4.3 Pitfalls of OCT in Retinal Diagnostics -- 4.3.1 Acquisition Protocol -- 4.3.2 Acquisition Technique -- 4.3.3 Interpretation -- 4.4 Summary and Outlook -- References -- 5: Ophthalmic Diagnostic Imaging: Glaucoma -- 5.1 Introduction -- 5.2 The Heidelberg Retina Tomograph: Confocal Scanning Laser Ophthalmoscope (cSLO) -- 5.2.1 Clinical Development -- 5.2.2 Clinical Validation. , 5.2.3 Surrogate Endpoints and Progression -- 5.2.4 Summary -- 5.3 SPECTRALIS SD-OCT -- 5.3.1 Clinical Assessment of Optic Nerve Head Parameters -- 5.3.2 Bruch's Membrane Opening (BMO) in SD-OCT-Based Neuroretinal Rim Measurements -- 5.3.3 Anatomic Variation: Position of the Fovea Relative to the Center of the ONH -- 5.3.4 Anatomic Variation: ONH size and Ocular Magnification Impact RNFL Measurements -- 5.3.5 Factors that May Confound Measurements and Classifications: Age, Axial length, and Tilted Discs -- 5.3.6 Posterior Pole: Macular and Asymmetry Analyses -- 5.3.7 Detection of Glaucomatous Progression with OCT -- 5.3.8 Summary -- 5.4 Summary and Outlook -- References -- 6: OCT Angiography (OCTA) in Retinal Diagnostics -- 6.1 Introduction -- 6.2 Technical Foundation for Clinical OCTA Imaging -- 6.2.1 OCTA Signal Processing and Image Construction -- 6.2.2 OCTA Data Visualization -- 6.2.3 Projection Methods -- 6.2.4 Retinal Vascular Plexuses -- 6.2.5 Quantification of OCTA Data -- 6.3 Image Artifacts and Countermeasures -- 6.3.1 Projection Artifacts -- 6.3.2 Segmentation Artifacts -- 6.3.3 Motion Artifacts -- 6.3.4 Lateral and Axial Resolution -- 6.4 Clinical Application of OCTA -- 6.4.1 Diabetic Retinopathy -- 6.4.2 Retinal Vein Occlusion -- 6.4.3 Macular Telangiectasia -- 6.4.4 Age Related Macular Degeneration -- 6.5 Conclusion -- References -- 7: OCT-Based Velocimetry for Blood Flow Quantification -- 7.1 Introduction -- 7.2 Clinical Potential for OCT-Based Retinal Blood Flow Measurements -- 7.3 Measuring Blood Flow with OCT -- 7.3.1 Phase-Based Methods -- 7.3.1.1 Theory -- 7.3.1.2 Application to Retinal Imaging -- Circumpapillary Scan -- En Face Plane Doppler OCT -- Multiple Beam Doppler OCT -- Digital Filtering in Full Field OCT -- Analysis of the Doppler Frequency Bandwidth. , 7.3.2 Amplitude Based Flow Quantification -- 7.3.2.1 Complex Amplitude: Dynamic Light Scattering Optical Coherence Tomography -- 7.3.2.2 Intensity: Speckle Decorrelation -- 7.3.2.3 Alternative Speckle Decorrelation Methods -- 7.4 Discussion and Conclusion -- References -- 8: In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells -- 8.1 Introduction -- 8.2 Holographic Optical Coherence Tomography -- 8.2.1 Optical Setup -- 8.2.2 Data Evaluation -- 8.3 IOS of the Human Photoreceptor Cells -- 8.3.1 Molecular Origin -- 8.3.2 Technical Limitations of FF-SS-OCT -- 8.3.3 Outlook -- References -- 9: Two-Photon Scanning Laser Ophthalmoscope -- 9.1 Introduction -- 9.1.1 Retinal Signaling -- 9.1.2 Imaging Retinal Neurons -- 9.1.3 Imaging Other Retinal Cell Types In Vivo -- 9.2 Theoretical Background -- 9.2.1 Luminescence, SPA and TPA -- 9.2.2 TPA Probability and Dependencies -- 9.2.3 Optical Resolution -- 9.2.4 Linear SPA vs. Nonlinear TPA Imaging -- 9.3 Experimental Setup and Results -- 9.4 Future Application of  Two-Photon Scanning Laser Ophthalmoscopy -- References -- 10: Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) -- 10.1 Introduction -- 10.2 Technical Realization Based on the Spectralis Platform -- 10.3 Clinical Applications I: The Healthy Eye -- 10.3.1 Macular Pigment -- 10.4 Clinical Applications II: AMD and Retinal Dystrophies -- 10.4.1 Age-Related Macular Degeneration -- 10.4.2 Retinal Dystrophies -- 10.5 Clinical Applications III: Macula Telangiectasia -- 10.5.1 Macular Telangiectasia -- 10.6 Clinical Applications IV: Diabetic Retinopathy -- 10.7 Conclusion and Summary -- References -- 11: Selective Retina Therapy -- 11.1 Retinal Therapy: A Short Historic Overview -- 11.2 The Concept and State of the Art of Selective Retina Therapy. , 11.2.1 Experimental Results -- 11.2.2 Clinical Study Results -- 11.2.3 Dosimetry and Dosing Control -- 11.3 OCT for SRT Dosimetry -- 11.3.1 Hypothesis of Fringe Washouts in M-Scan OCT -- 11.3.2 First Pre-clinical and Clinical Studies -- 11.3.3 Future Developments Towards Reliably Detecting the Microbubble Threshold with OCT -- 11.4 SRT Module Integration into the OCT Platform -- 11.5 Conclusions and Outlook -- References -- Part III: Anterior Segment Imaging and Image Guided Treatment -- 12: In Vivo Confocal Scanning Laser Microscopy -- 12.1 Introduction -- 12.2 Principle of Confocal Scanning Laser Microscopy -- 12.3 In Vivo cSLM with the Rostock Cornea Module -- 12.4 Ophthalmological Applications -- 12.4.1 Diagnoses of Keratomycosis -- 12.4.2 Subbasal Nerve Plexus -- 12.4.3 Corneal Keratocyte: A Neglected Entity of Cells -- 12.4.4 cSLM for Animal Studies -- 12.4.5 Interdisciplinary Research -- 12.5 Non-ophthalmological Applications -- 12.6 Current and Future Developments -- 12.6.1 Subbasal Nerve Plexus Mosaicking -- 12.6.2 Slit Lamp Microscopy on a Cellular Level Using In Vivo Confocal Laser Scanning Microscopy -- 12.6.3 OCT-Guided In Vivo Confocal Laser Scanning Microscopy -- 12.6.4 Multiphoton Microscopy -- 12.7 Summary -- References -- 13: Anterior Segment OCT -- 13.1 Introduction -- 13.2 Anterior Segment Spectral-Domain OCT (SD-OCT) -- 13.3 Anterior Segment Swept Source OCT (SS-OCT) -- 13.3.1 SS-OCT and Cornea Evaluation -- 13.3.2 SS-OCT and Cataract Evaluation -- 13.3.3 SS-OCT and Anterior Chamber Evaluation -- 13.3.4 SS-OCT and Anterior Segment Imaging -- 13.4 Summary and Outlook -- References -- 14: Femtosecond-Laser-Assisted Cataract Surgery (FLACS) -- 14.1 Introduction -- 14.2 Cataract and Surgery -- 14.3 History of Femtosecond-Laser-Assisted Cataract Surgery. , 14.4 All-Solid-State Chirped-Pulse-Amplification Femtosecond Laser.

Additional Edition: Print version: Bille, Josef F. High Resolution Imaging in Microscopy and Ophthalmology Cham : Springer International Publishing AG,c2019 ISBN 9783030166373

Language: English

Subjects: Medicine

Keywords: Electronic books.

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Format: 1 online resource (239 pages)

Edition: 1st ed.

ISBN: 9783030138646

Note: Intro -- Contents -- Introduction -- 1: Historical Terminology, Classifications, and Present Definition of DCM -- 1.1 Dilated Cardiomyopathies: The Classification Pathway -- 1.2 Genetic Dilated Cardiomyopathy and Etiological Classification -- 1.3 Future Perspectives -- References -- 2: Epidemiology -- 2.1 Towards Contemporary Clinical Epidemiology in Dilated Cardiomyopathy -- 2.2 Genetics and Future Perspectives -- References -- 3: Pathophysiology -- 3.1 Ventricular Remodeling in DCM -- 3.2 Genetic Pathophysiology and New Possible Proteins Involved in DCM [2] -- 3.3 Molecular Mechanisms of Cardiac Remodeling in HF [15] -- References -- 4: Etiological Definition and Diagnostic Work-Up -- 4.1 Clinical Presentation -- 4.2 Etiological Classification: A Critical Issue in Clinical Management of DCM -- 4.2.1 Need of Reclassification of the Disease During Follow-Up -- 4.3 Exclusion of Reversible Causes of Left Ventricular Dysfunction/Dilation -- 4.4 Diagnostic Work-Up in New-Onset LV Dysfunction/Dilation: A "Red Flags" Approach -- 4.4.1 Personal and Family History -- 4.4.2 Symptoms and Physical Examination -- 4.4.3 12 Lead Electrocardiogram -- 4.4.4 Laboratory Tests -- 4.4.4.1 Genetic Testing -- 4.4.5 Echocardiography -- 4.4.6 Cardiovascular Magnetic Resonance -- 4.4.7 Cardiac Catheterizations and Procedures -- 4.4.7.1 Coronary Angiogram -- 4.4.7.2 Cardiac Catheterization -- 4.4.7.3 Endomyocardial Biopsy -- 4.5 Conclusions -- References -- 5: Genetics of Dilated Cardiomyopathy: Current Knowledge and Future Perspectives -- 5.1 DCM-Associated Genes -- 5.1.1 Titin -- 5.1.2 Lamin A/C -- 5.1.3 Structural Cytoskeleton Z-Disk Genes -- 5.1.4 Desmosomal Genes -- 5.1.5 Sarcomeric (Motor) Genes -- 5.1.6 Ion Channel-Related Genes -- 5.1.7 Other Genes -- 5.2 Technical Issues in Genetic Sequencing. , 5.3 The Complexity in Variant Classification Process -- 5.4 The External Modulation of Genotype: Environmental Triggers -- 5.5 Evidence-Based Genotype-Phenotype Correlations -- 5.5.1 Lamin A/C -- 5.5.2 Titin -- 5.5.3 Filamin C -- 5.5.4 Insights from Clinical Presentation and Left Ventricular Reverse Remodeling (LVRR) -- References -- 6: Clinical Presentation, Spectrum of Disease, and Natural History -- 6.1 Spectrum of Disease -- 6.2 Clinical Presentation -- 6.3 Natural History -- References -- 7: Role of Cardiac Imaging: Echocardiography -- 7.1 Echocardiographic Features of Dilated Cardiomyopathy -- 7.2 Role of New Echocardiographic Techniques -- 7.3 Clinical Echocardiography in DCM: Advantages and Limitations in Clinical Practice -- 7.4 Prognostic Role of Echocardiographic Data in DCM -- References -- 8: Role of Cardiac Imaging: Cardiac Magnetic Resonance and Cardiac Computed Tomography -- 8.1 Cardiac Magnetic Resonance -- 8.2 Diagnostic Accuracy -- 8.3 Differential Diagnosis -- 8.4 Myocarditis Presenting as Left Ventricular Dysfunction -- 8.5 Other Secondary Forms of DCM -- 8.6 Prognostic Stratification -- 8.7 Macroscopic vs. Diffuse Fibrosis -- 8.8 Strain Analysis -- 8.9 Other Prognostic Indicators -- 8.10 Computed Tomography -- References -- 9: Endomyocardial Biopsy -- 9.1 Introduction -- 9.2 Technique -- 9.3 Complications -- 9.4 Indications in DCM Scenarios -- 9.5 Diagnosis of Myocarditis -- 9.6 Examples of Endomyocardial Biopsy -- 9.6.1 Case I (J.D.) -- 9.6.2 Case II (C.P.) -- 9.6.3 Case III (C.S.) -- 9.6.4 Case IV (C.F.) -- References -- 10: Arrhythmias in Dilated Cardiomyopathy: Diagnosis and Treatment -- 10.1 Burden and Kinds of Arrhythmias in Dilated Cardiomyopathy: Risk Stratification of Sudden Death -- 10.1.1 Bradyrhythmias and Conduction Abnormalities -- 10.1.2 Supraventricular Arrhythmias. , 10.1.3 Ventricular Arrhythmias -- 10.1.4 Mechanisms -- 10.1.5 Risk Stratification of Sudden Cardiac Death -- 10.1.6 Role of Supraventricular and Ventricular Arrhythmias in Pathogenesis of DCM -- 10.1.6.1 Definition and Pathophysiology -- 10.1.6.2 Specific Clinical Pictures -- 10.1.7 Management of Atrial Arrhythmias in Dilated Cardiomyopathy and Heart Failure -- 10.1.8 Management of Ventricular Arrhythmias in Dilated Cardiomyopathy -- 10.1.9 Antiarrhythmic Drug Therapy of Ventricular Arrhythmias -- 10.1.10 Catheter Ablation of Ventricular Arrhythmias -- 10.1.11 Characteristics of the Arrhythmogenic Substrate and Its Impact on Catheter Ablation Approach -- 10.1.12 Role of ICD in DCM -- References -- 11: Regenerative Medicine and Biomarkers for Dilated Cardiomyopathy -- 11.1 Strategies for Heart Regeneration -- 11.1.1 Cell Therapy -- 11.1.2 Gene Therapy -- 11.2 Regenerative Approaches in Dilated Cardiomyopathy -- 11.3 Biomarkers and Dilated Cardiomyopathy -- References -- 12: Prognostic Stratification and Importance of Follow-Up -- 12.1 Prognosis of DCM: The Milestones of the Management -- 12.2 Etiological Characterization as an Important Prognostic Factor -- 12.3 DCM as a Dynamic Disease: The Importance of Follow-Up -- 12.4 Left Ventricular Reverse Remodeling Beyond the Left Ventricle -- 12.5 Prognostic Role of Cardiopulmonary Exercise Testing -- 12.6 Arrhythmic Risk Stratification -- 12.7 The "Apparent Healing" Phenomenon -- 12.8 Uninterrupted Follow-Up and Continuous Reclassification of the Disease -- References -- 13: Current Management and Treatment -- 13.1 Familial Screening Program -- 13.2 Sport Activity Screening Program -- 13.3 Medical Treatment -- 13.4 Ventricular and Supraventricular Arrhythmias -- 13.5 Implantable Cardioverter-Defibrillator -- 13.6 Cardiac Resynchronization Therapy. , 13.7 Advanced Heart Failure, Mechanical Circulatory Support, Functional Mitral Regurgitation Correction, Heart Transplantation, and Palliative Care -- References -- 14: Unresolved Issues and Future Perspectives -- 14.1 Toward a Personalized Medicine: A Genetic Approach -- 14.2 The Challenge of Arrhythmic Stratification -- 14.3 Toward Innovation in Therapy -- References -- 15: Dilated Cardiomyopathy at the Crossroad: Multidisciplinary Approach -- 15.1 Sarcoidosis: Co-working with Pneumologists -- 15.1.1 Treatment -- 15.2 Autoimmune Cardiomyopathy: Co-working with Rheumatologists -- 15.2.1 Systemic Lupus Erythematosus -- 15.2.2 Treatment -- 15.3 Infectious Disease and Cardiomyopathy: Co-working with Infectious Disease Specialist -- 15.3.1 Chagas Cardiomyopathy -- 15.3.2 Treatment -- 15.3.3 Lyme Disease -- 15.3.4 Treatment -- 15.4 Dilated Cardiomyopathy Associated with Neuromuscular Diseases: Co-working with Neurologists -- 15.5 Primary Iron-Overload Cardiomyopathy: Co-working with the Hematologists -- 15.6 Cardiomyopathy Related to Chemotherapeutic Agents: Co-working with Oncologists -- 15.6.1 Treatment -- 15.7 Alcoholic Cardiomyopathy -- 15.7.1 Treatment -- References.

Additional Edition: Print version: Sinagra, Gianfranco Dilated Cardiomyopathy Cham : Springer International Publishing AG,c2019 ISBN 9783030138639

Language: English

Subjects: Medicine

Keywords: Electronic books.

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URL: https://doi.org/10.1007/978-3-030-13864-6

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ISBN: 9783030111144

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Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-030-11115-1

Language: English

Subjects: Medicine

Keywords: Medizin ; Mikrobiologie ; Infektionskrankheit ; Aufsatzsammlung ; Electronic books. ; Index not Present.

DOI: 10.1007/978-3-030-11114-4

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Format: 1 online resource (199 pages)

ISBN: 9783030043636

Series Statement: Philosophical Studies Ser. ; v.137

Note: Intro -- Preface and Acknowledgments -- Contents -- Contributors -- Chapter 1: Ethical Medical Data Donation: A Pressing Issue -- 1.1 Background -- 1.2 Current Debates -- 1.3 This Volume and Its Chapters -- References -- Part I: Conceptualising the Ethics of Medical Data Donation -- Chapter 2: Data Donation: How to Resist the iLeviathan -- 2.1 Data Use in the Era of GAFA -- 2.2 What Does It Mean to Donate Data? -- 2.2.1 Donation as a Relational Practice -- 2.2.2 Can We Donate Data? -- 2.3 Considerations for Frameworks for Data Donation -- 2.3.1 Relationality -- 2.3.2 Indirect Reciprocity -- 2.3.3 Multiplicity -- 2.4 Resisting the iLeviathan? Politicising the Ethics of Data Donation -- References -- Chapter 3: Data Donations as Exercises of Sovereignty -- 3.1 Introduction -- 3.2 Donations and Sovereignty -- 3.3 Reasons in Favour of Data Donations -- 3.3.1 Solidarity -- 3.3.2 Beneficence -- 3.3.3 Participation -- 3.4 Challenges with Data Donations -- 3.4.1 Trust -- 3.4.2 Future Use -- 3.4.3 Invasiveness -- 3.4.4 Ownership -- 3.4.5 Affected People -- 3.4.6 Voluntariness -- 3.5 Donations, Consent and Control -- 3.5.1 Consent -- 3.5.2 Representation -- 3.5.3 Organizations -- 3.5.4 Observation I -- 3.5.5 Observation II -- 3.6 Conclusion -- References -- Chapter 4: The Ethics of Uncertainty for Data Subjects -- 4.1 Uncertainty and Data Ethics -- 4.2 What Features of Data Practices Create Unknowns? -- 4.2.1 Open-Endedness -- 4.2.2 Opacity -- 4.2.3 Persistence -- 4.2.4 Endemic Uncertainties Combined -- 4.3 Two Epistemic Interests of Data Subjects -- 4.3.1 Interests in Trust -- 4.3.2 Interests in Knowing Our Own Obligations -- 4.4 Strategies for Mitigating Uncertainty -- 4.4.1 Systemic Resilience Through Flexible Systemic Oversight -- 4.4.2 Hazard Reduction Through Privacy-by-Design -- 4.4.3 Concluding Reflections -- References. , Chapter 5: Incongruities and Dilemmas in Data Donation: Juggling Our 1s and 0s -- 5.1 Introduction -- 5.2 Hast Thou Which Art but Data, a Touch, a Feeling? -- 5.3 What We Might Be Donating -- 5.4 Are We at Least with Socrates? -- 5.5 Legal Position - Data vs Tissue -- 5.6 No Man Is an Island Entire of Itself -- 5.7 Data, Data Everywhere, nor any Chance to Think -- 5.8 Up in the Air -- 5.9 Through a Glass Darkly -- 5.10 Life Through a Lens (Or Several) -- 5.11 Minding Our Ps and Qs -- 5.12 The Need for Innovation in Data Governance -- 5.13 Who Are You, Who, Who, Who, Who? -- 5.14 Finding the Black Cat in the Dark Room -- 5.15 Conclusion -- References -- Part II: Governance and Regulation of Medical Data Donation -- Chapter 6: Posthumous Medical Data Donation: The Case for a Legal Framework -- 6.1 Introduction -- 6.2 Legal Protection of Health-Related Data of the Living and the Dead in the UK -- 6.2.1 The Protection of the Data of the Deceased in the Health Sector -- 6.3 Some Issues Around Ownership, Privacy, Control and Succession of Data -- 6.4 A Comparable Regime: Organ Donation -- 6.5 International Framework - Code or Law? -- 6.6 Conclusion -- References -- Chapter 7: Medical Data Donation, Consent and the Public Interest After Death: A Gateway to Posthumous Data Use -- 7.1 Data Governance and the Promise of PMDD -- 7.2 Timing, Interests and the Limits of Consent -- 7.2.1 A Matter of Timing -- 7.2.2 Interests in PMDD -- 7.2.3 Models of Consent -- 7.3 Authorisation and the Role of the Public Interest -- 7.4 Conclusion -- References -- Part III: Implementing Ethical Medical Data Donation -- Chapter 8: The Personal Data Is Political -- 8.1 Introduction -- 8.2 Sharing Genomic Data -- 8.3 Sharing Neurobiological Data -- 8.4 Data Sharing as a Social Movement -- References. , Chapter 9: Personal Data Cooperatives - A New Data Governance Framework for Data Donations and Precision Health -- 9.1 The Unique Features of Personal Data -- 9.2 The Need - Aggregated Datasets on Millions of People -- 9.3 The Opportunity - The Legal Right of Citizens to Obtain Copies of Their Personal Data and Their Willingness to Contribute These Data to Research -- 9.3.1 The European General Data Protection Regulation (GDPR) - Data Portability -- 9.3.2 The Willingness and the Right to Citizen Science -- 9.4 The Challenge -- 9.5 The Solution - Data Cooperatives and Personal Data, a Perfect Match -- 9.5.1 Data Cooperatives, Business Model, Non-profit, Financial Incentives -- 9.5.2 Challenges to the Cooperative Model -- 9.5.3 Example: MIDATA Data Cooperative -- 9.5.4 The Data Platform and Governance Form the Core of a New Innovation Ecosystem -- 9.6 Data Cooperatives and Data Donations -- References -- Chapter 10: Defining Data Donation After Death: Metadata, Families, Directives, Guardians and the Route to Big Consent -- 10.1 Introduction -- 10.2 Defining Data Donation After Death -- 10.3 Data Donation Metadata -- 10.4 Data Advance Directives -- 10.5 Posthumous Data Guardians -- 10.6 Objections -- 10.7 Other Governance Mechanisms -- 10.8 Conclusion -- References -- Part IV: An Ethical Code for Posthumous Medical Data Donation -- Chapter 11: Enabling Posthumous Medical Data Donation: A Plea for the Ethical Utilisation of Personal Health Data -- 11.1 Introduction -- 11.2 What Is Posthumous Medical Data Donation? -- 11.3 Why We Should Enable PMDD -- 11.4 How Does PMDD Compare to Other Biomedical Donations? -- 11.4.1 Key Differences Among Existing Biomedical Donation Schemes -- 11.5 The Need for an Ethical Code -- 11.6 How to Implement Ethical PMDD -- 11.6.1 Learning from Mistakes and Codifying Best Practice. , 11.6.2 Deriving Relevant Ethical Principles -- 11.7 Conclusion -- References -- Chapter 12: An Ethical Code for Posthumous Medical Data Donation -- 12.1 Preamble -- 12.2 Considerations -- 12.3 Definitions -- 12.4 Overview -- 12.4.1 Objectives -- 12.4.2 Scope -- 12.5 Foundational Ethical Principles -- 12.5.1 Human Dignity and Respect for Persons -- 12.5.2 Promotion of the Common Good -- 12.5.3 The Right to Citizen Science -- 12.5.4 Quality and Good Data Governance -- 12.5.5 Transparency, Trust, and Integrity -- 12.6 Obtaining PMRs for Research Purposes -- 12.6.1 Obtaining Consent -- 12.6.2 Persons Unable to Give Consent -- 12.6.3 Changing or Withdrawing Consent -- 12.6.4 Refusing Donations -- 12.6.4.1 Refusing a PMDD on Grounds of the Data's Nature -- 12.6.4.2 Refusing a PMDD on Grounds of the Data Source -- 12.6.4.3 Other Grounds for Refusing a PMDD -- 12.7 Research Approval, Conduct and Oversight -- 12.7.1 General Principles -- 12.7.1.1 Prohibition of Financial Gain -- 12.7.1.2 Confidentiality -- 12.7.1.3 Data Custody -- 12.7.1.4 Data Protection -- 12.7.1.5 Directly Identifiable Data -- 12.7.1.6 Information on Health and Hereditary Disease -- 12.7.2 Research Access -- 12.7.2.1 Access Requests -- 12.7.2.2 Research Results -- 12.7.3 Research Oversight -- 12.7.4 Contingency Planning -- References -- Index.

Additional Edition: Print version: Krutzinna, Jenny The Ethics of Medical Data Donation Cham : Springer International Publishing AG,c2019 ISBN 9783030043629

Language: English

Subjects: Medicine

Keywords: Electronic books. ; Electronic books.

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Format: xxx, 768 Seiten : , Illustrationen, Karte.

ISBN: 978-0-19-021950-5 , 978-0-19-755437-1

Series Statement: Oxford handbooks

Content: Community music as a field of practice, pedagogy, and research has come of age. The past decade has witnessed an exponential growth in practices, courses, programs, and research in communities and classrooms, and within the organizations dedicated to the subject. The Oxford Handbook of Community Music gives an authoritative and comprehensive review of what has been achieved in the field to date and what might be expected in the future. This Handbook addresses community music through five focused lenses: contexts, transformations, politics, intersections, and education. It not only captures the vibrant, dynamic, and divergent approaches that now characterize the field, but also charts the new and emerging contexts, practices, pedagogies, and research approaches that will define it in the coming decades. The contributors to this Handbook outline community music's common values that center on social justice, human rights, cultural democracy, participation, and hospitality from a range of different cultural contexts and perspectives. As such, The Oxford Handbook of Community Music provides a snapshot of what has become a truly global phenomenon. - Brydie-Leigh Bartleet is Associate Professor and Director of the Queensland Conservatorium Research Centre at Griffith University, Australia. Lee Higgins is Professor of Music Education and Director of the International Centre for Community Music at York St John University. He is also the author of Community Music: In Theory and In Practice (2012).

Note: Hier auch später erschienene, unveränderte Nachdruck. - First issued as an Oxford University Press paperback, 2021

Additional Edition: Erscheint auch als Online-Ausgabe ISBN 978-0-19-021952-9

Language: English

Subjects: Musicology

Keywords: Musik ; Gemeinschaft ; Musikleben ; Musizieren ; Soziale Funktion ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung

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