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  • 1
    UID:
    gbv_1620111403
    Format: VI, 290 S. , zahlr. Ill., graph. Darst., Kt.
    ISBN: 9783700172444
    Series Statement: Veröffentlichungen zur Sozialanthropologie Bd. 18
    Note: The camel at the crossroads of multiple perspectives : introduction to an interdisciplinary encounter / Eva-Maria Knoll (Vienna)Genetic traces of domestication in Old World camelids / Pamela Burger (Vienna) -- The encounter between Bactrian and Dromedary camels in Central Asia / Bernard Faye (Montpellier), Gaukhar Konuspayeva (Montpellier) -- Embryonic hump development and ancestry in old world camels / Clemens Knospe (Munich), Joerg Kinne (Dubai), Nissar A. Wani (Dubai), Ulrich Wernery (Dubai), Joris Peters (Munich) -- The conservation status and management of wild camels in Mongolia / Adiya Yadamsuren (Ulaanbaatar), Enkhbileg Dulamtseren (Ulaanbaatar), Richard P. Reading (Denver) -- The status of the wild camel in China / Yuan Li (Xinjiang), John Hare (Benenden), Yuan Guoying (Xinjiang), Cheng Yun (Xinjiang) -- Working in a freezer: capturing and collaring wild Bactrian camels / Chris Walzer (Vienna), Petra Kaezensky (Vienna), Enkhbileg Dulamtseren (Ulaanbaatar), Adiya Yadamsuren (Ulaanbaatar) -- Hybridization: a threat to the genetic distinctiveness of the last wild old world camel species / Katja Silbermayr (Vienna), Pamela Burger (Vienna) -- Ancient DNA reveals domestication process: the case of the two-humped camel / Alexandra Trinks (Mainz), Pamela Burger (Vienna), Norbert Benecke (Berline) Joachim Burger (Mainz) -- The tears of the camel : reflections on depictions and descriptions of the camel in Mongolian culture / Maria-Katharina Lang (Vienna) -- The camel and its symbolism in the daily life of the Mongols with particular reference to their folk songs / Otgonbayar Chuluunbaatar (Vienna) -- Archeozoology of camels in South-Eastern Arabia / Margarethe Uerpmann (Tübingen) -- Riding camels in Arabia : outline of a revised cultural history / Walter Dostal (Vienna) -- Caravans from South Arabia : roads and organization / Johann Heiss (Vienna) -- Camels in star mythology and in everyday rural life : ethnographic observations in South-West Arabia's Tihāma lowlands / Andre Gingrich (Vienna) -- What camels eat : a study of Arabic ethnobotany / Daniel Martin Varisco (New York) -- The economic significance and traditional management of dromedaries in Syria / Darem Tabbaa (Hama) -- The socio-economic perspective of camels in Pakistan / Arshad Iqbal (Rawalpindi) -- Camel trekking in Jordan: between oriental perception and authentic tourist expectation / Mohammed Shunnaq (Irbid), Susanne Ramadan Shunnaq (Irbid) -- Camel urine and milk in the Arab heritage (folk medicine) : a review / Abdulsalam A. Bakhsh (Al-Ahsa), Wael M. El-Deeb (Al-Ahsa), Awatif A. Al-Judaibi (Jeddah) -- The Saharan dromedary as a sign : the prominence of dromedaries among the Nomadic Imuhar Society in the Algerian desert / Anja Fischer (Vienna) -- The traditional management of the one-humped camel in the Horn of Africa : milking, fostering and weaning techniques / Maurizio Dioli (Alicante) -- The informal camel milk marketing sector in Kenya and Somalia / Mario Younan (Nairobi), David M. Mwangi (Nairobi) -- Extending the shelf life of camel milk / Ibtisam E.M. El Zubeir (Khartoum) -- Bringing camels into focus : a photo-essay on dromedaries in the Nigeria-Niger corridor / Abdussamad M. Abdussamad (Göttingen/Nigeria), Demo Joab Usman Kalla (Aberdeen), Shehu Ahmad Maigandi (Sokoto)
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Asien ; Nordafrika ; Kamel ; Asien ; Nordafrika ; Kamel ; Aufsatzsammlung
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  • 2
    Online Resource
    Online Resource
    Cambridge, United Kingdom : Cambridge University Press
    UID:
    gbv_1653733586
    Format: 1 Online-Ressource (xxx, 354 Seiten)
    ISBN: 9781108436427
    Series Statement: State of the apes 2017
    Content: Infrastructure development in Africa and Asia is expanding at breakneck speed, largely in biodiversity-rich developing nations. The trend reflects governments’ efforts to promote economic growth in response to increasing populations, rising consumption rates and persistent inequalities. Large-scale infrastructure development is regularly touted as a way to meet the growing demand for energy, transport and food—and as a key to poverty alleviation. In practice, however, road networks, hydropower dams and “development corridors” tend to have adverse effects on local populations, natural habitats and biodiversity. Such projects typically weaken the capacity of ecosystems to maintain ecological functions on which wildlife and human communities depend, particularly in the face of climate change. This volume—State of the Apes: Infrastructure Development and Ape Conservation—presents original research and analysis, topical case studies and emerging tools and methods to inform debate, practice and policy with the aim of preventing and mitigating the harmful impacts of infrastructure projects on biodiversity. Using apes as a proxy for wildlife and cosystems themselves, it identifies opportunities for reconciling economic and social development with environmental stewardship.
    Additional Edition: ISBN 9781108423212
    Additional Edition: ISBN 9781108436410
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 1029092303
    Language: English
    Subjects: Agriculture, Forestry, Horticulture, Fishery, Domestic Science , Biology
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    Keywords: Affen ; Tierschutz
    URL: Volltext  (kostenfrei)
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  • 3
    Book
    Book
    Austin : Univ. of Texas Press
    UID:
    b3kat_BV010041517
    Format: XV, 183 S. , Ill., graph. Darst., Kt.
    ISBN: 0292776780 , 0292776802
    Content: "When construction of the Transamazon Highway was proposed in 1970, the Brazilian media depicted a road stretching out through a flat expanse of mature forests, its surface paved with glittering stones and precious metals - purported riches of the Amazon yet to be discovered." But, as Douglas Stewart found while traveling the highway in 1989, "the forest deceives." The 1,000-kilometer trip from Belem to Altamira took "three days, six buses, three boats, and a ten-hour hitch with a truck driver named Eduardo."
    Content: This lively, readable study explores why colonzation of the Amazon fell, short of the planners' vision. Delving into issues of land distribution, soil ecology, and the colonists' adaptation to local ecosystems, Stewart uncovers the forces that drive deforestation. In particular, he shows how soil quality and the concentration of land among large landholders have shaped the entire landscape of colonized Amazonia, encouraging the spread of cattle ranching into the many infertile areas and causing destruction of the forest's rich diversity of plant and animal species. Recounting fascinating stories of the colonists he encountered in his travels, Stewart also shows how small farmers have banded together during the past decade to overcome the challenges of the frontier, from poor roads to low prices for agricultural goods. Their collective action, he asserts, if backed by government policy, could lead to progressive land redistribution and wiser use
    Content: This broad-ranging look at why deforestation has occurred in the Amazon, what its consequences are, and what can be done to halt and remedy the process should be read by everyone concerned with preserving the Latin American environment. As Douglas Stewart concludes, "if I'm lucky, mine may become one of those little books that makes good because it takes a simple idea and puts it into practice.
    Language: English
    Subjects: Agriculture, Forestry, Horticulture, Fishery, Domestic Science , Biology
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    Keywords: Brasilien ; Kleinbauer ; Brasilien ; Entwaldung ; Amazonas-Gebiet ; Entwaldung ; Amazonas-Gebiet ; Kleinbauer
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  • 4
    Book
    Book
    Cambridge : Royal Society of Chemistry
    UID:
    b3kat_BV047663094
    Format: xli, 251 Seiten , Illustrationen, Diagramme
    Edition: 2nd edition
    ISBN: 9781788013659
    Series Statement: Chemical biology No. 19
    Additional Edition: Erscheint auch als Online-Ausgabe, PDF ISBN 978-1-83916-056-1
    Additional Edition: Erscheint auch als Online-Ausgabe, EPUB ISBN 978-1-83916-066-0
    Language: English
    Subjects: Biology
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  • 5
    Online Resource
    Online Resource
    Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg
    UID:
    gbv_1649970064
    Format: Online-Ressource (XIV, 280p. 22 illus., 11 illus. in color, digital)
    ISBN: 9783642030451
    Series Statement: Results and Problems in Cell Differentiation 49
    Content: Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events. Besides their role in the induction of cell death, evidence now exists that death receptors are able to activate several non-apoptotic signaling pathways which, depending on cellular context, may lead to apoptosis resistance, secretion of pro-inflammatory proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role of death receptors in cancer development.
    Note: Includes bibliographical references and index , 400_Results_FM_O.pdf; 400_Results_Ch01_O.pdf; The Role of TNF in Cancer; 400_Results_Ch02_O.pdf; Many Checkpoints on the Road to Cell Death: Regulation of Fas-FasL Interactions and Fas Signaling in Peripheral Immune Response; 400_Results_Ch03_O.pdf; FasL Expression and Reverse Signalling; 400_Results_Ch04_O.pdf; Impact of TNF-R1 and CD95 Internalization on Apoptotic and Antiapoptotic Signaling; 400_Results_Ch05_O.pdf; Ubiquitination and TNFR1 Signaling; 400_Results_Ch06_O.pdf; From Biochemical Principles of Apoptosis Induction by TRAIL to Application in Tumour Therapy; 400_Results_Ch07_O.pdf , Therapeutic Targeting of TWEAK/Fn14 in Cancer: Exploiting the Intrinsic Tumor Cell Killing Capacity of the Pathway400_Results_Ch08_O.pdf; APRIL in B-cell Malignancies and Autoimmunity; 400_Results_Ch09_O.pdf; Autophagy in Cancer and Chemotherapy; 400_Results_Ch10_O.pdf; Glucocorticoid-Mediated Apoptosis Resistance of Solid Tumors; 400_Results_Ch11_O.pdf; Targeting Death-Receptors in Radiation Therapy; 400_Results_Ch12_O.pdf; Death Ligands Designed to Kill: Development and Application of Targeted Cancer Therapeutics Based on Proapoptotic TNF Family L; 400_Results_Index_O.pdf
    Additional Edition: ISBN 9783642030444
    Additional Edition: Buchausg. u.d.T. Death receptors and cognate ligands in cancer Heidelberg : Springer, 2009 ISBN 9783642030444
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Krebs ; Zelltod ; Tumor-Nekrose-Faktor ; Rezeptor ; Ligand ; Signaltransduktion ; Krebs ; Zelltod ; Tumor-Nekrose-Faktor ; Rezeptor ; Ligand ; Signaltransduktion ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 6
    Online Resource
    Online Resource
    London : Elsevier
    UID:
    gbv_1652219714
    Format: Online Ressource (xvi, 97 p.)
    Edition: Online-Ausg.
    ISBN: 0123877369 , 9780123877369 , 9780123877529 , 9781283363204 , 1283363208
    Series Statement: Elsevier insights
    Content: 2.4 Genome Biology of Coconut Endosperm and Fatty Acid Biosynthesis2.5 Coconut Tissue Culture-Related Genes; 2.6 Structural Biology of Hirsutellin; 2.7 Road Map for Coconut Genomics; References; 3 Oil Palm; 3.1 Introduction; 3.2 Markers, QTLS, Omics of Mesocarp, and Shell Thickness; 3.2.1 Markers and Genes for Shell Thickness; 3.2.2 Omics of Oil Palm Mesocarp Biology; 3.3 Transcriptomics and Genes of Somatic Embryogenesis and Mantled Disorder; 3.4 Molecular Markers for QTL Mapping and Diversity Analysis in Oil Palm; 3.5 Genes and Promoters of Oil Palm; 3.6 Bioinformatics
    Content: 3.7 Haploid Technologies3.8 Road Map for Oil Palm Genomics; References; 4 Date Palm; 4.1 Introduction; 4.2 Genetic Diversity using Molecular Markers; 4.2.1 Amplified Fragment Length Polymorphism; 4.2.2 RAPD, SSR, and ISSR Markers; 4.3 Molecular Biology of Sex Determination; 4.4 Resistance to Bayoud Disease; 4.5 Probes for Brittle Leaf Disease; 4.6 Somaclonal Variations, DNA Methylation, and Other Markers; 4.7 Complete Genomes, SNPs, and Genomic Libraries; 4.8 Proteomics; 4.9 Road Map for Date Palm Genomics; References; 5 Rattans and Palmyra; 5.1 Introduction; 5.2 Molecular Markers for Rattans
    Content: 5.2.1 Molecular Phylogeny5.2.2 Molecular Markers for Diversity in Rattans; 5.2.3 Marker-Sex Association in Rattans; 5.3 Molecular Markers for Diversity and Sex Association in Palmyra; References; 6 Arecanut; 6.1 Diversity of Areca; 6.2 Molecular Phylogeny of Areca; 6.3 Arecanut and Health Hazards; 6.4 Biomarkers for Arecoline-Induced Damage; 6.5 Xenobiosis, Metabolomics, and Pharmacogenomics; 6.6 Areca Damage and Herbal Remedies; 6.7 Road Map for Areca Genomics; References; 7 Peach Palm; 7.1 Introduction; 7.2 Molecular Phylogeny of Bactridinae
    Content: 7.3 Biochemical and Molecular Markers in Peach Palm7.4 Polyphenol Oxidase, Carotenoids, and Antioxidants in Bactris; References; 8 Ornamental, Underutilized, and Vulnerable Palms; 8.1 Attalea, Butia, Carpentaria and Ceroxylon; 8.2 Chamaedorea and Euterpe; 8.3 Geonoma, Howea, Johannesteijsma, Livistona, Licuala, Lodoicea and Metroxylon; 8.4 Nypa, Oenocarpus, Pinanga, and Pseudophoenix; 8.5 Conclusions; References; 9 Molecular Phylogeny of Palms; 9.1 Introduction; 9.2 Random Primers and DNA Barcodes [2-5]; 9.3 Markers for Palms from Other Monocot Plants [7-9]; 9.4 Slow Evolution in Palms
    Content: Bioinformatics offers novel tools and resources to analyze plant genomes and genes. The complete genomes of two important commercial palms (dates and oil palm) have recently been sequenced. This offers scope for many computational tools to decipher the synteny, collinearity and common and unique genes of palms. This book reviews the latest developments in this field. Includes the latest information on the molecular breeding and bioinformatics of palmsCovers past and current work and future opportunitiesWritten in simple language avoiding technical
    Content: Front Cover; Genomics of Cultivated Palms; Copyright Page; Contents; Preface; Acknowledgments; Abbreviations; 1 Introduction; 1.1 Palms: Taxonomy and Uses; 1.2 Genetics Cytology and Genomics of Palms; 1.3 Molecular Phylogeny and Evolution; 1.4 Marker-Trait Associations; 1.5 Molecular Cloning and Transgenics; 1.6 Cross-Transferrable Microsatellite Markers in Palms; 1.7 Databases and Software; 1.8 Constraints and Opportunities in Genomics of Palms; References; 2 Coconut; 2.1 Introduction; 2.2 Markers for Assessment of Diversity; 2.3 Maker-Trait Associations, QTL Mapping on Coconut
    Note: Includes bibliographical references , Front Cover; Genomics of Cultivated Palms; Copyright Page; Contents; Preface; Acknowledgments; Abbreviations; 1 Introduction; 1.1 Palms: Taxonomy and Uses; 1.2 Genetics Cytology and Genomics of Palms; 1.3 Molecular Phylogeny and Evolution; 1.4 Marker-Trait Associations; 1.5 Molecular Cloning and Transgenics; 1.6 Cross-Transferrable Microsatellite Markers in Palms; 1.7 Databases and Software; 1.8 Constraints and Opportunities in Genomics of Palms; References; 2 Coconut; 2.1 Introduction; 2.2 Markers for Assessment of Diversity; 2.3 Maker-Trait Associations, QTL Mapping on Coconut , 2.4 Genome Biology of Coconut Endosperm and Fatty Acid Biosynthesis2.5 Coconut Tissue Culture-Related Genes; 2.6 Structural Biology of Hirsutellin; 2.7 Road Map for Coconut Genomics; References; 3 Oil Palm; 3.1 Introduction; 3.2 Markers, QTLS, Omics of Mesocarp, and Shell Thickness; 3.2.1 Markers and Genes for Shell Thickness; 3.2.2 Omics of Oil Palm Mesocarp Biology; 3.3 Transcriptomics and Genes of Somatic Embryogenesis and Mantled Disorder; 3.4 Molecular Markers for QTL Mapping and Diversity Analysis in Oil Palm; 3.5 Genes and Promoters of Oil Palm; 3.6 Bioinformatics , 3.7 Haploid Technologies3.8 Road Map for Oil Palm Genomics; References; 4 Date Palm; 4.1 Introduction; 4.2 Genetic Diversity using Molecular Markers; 4.2.1 Amplified Fragment Length Polymorphism; 4.2.2 RAPD, SSR, and ISSR Markers; 4.3 Molecular Biology of Sex Determination; 4.4 Resistance to Bayoud Disease; 4.5 Probes for Brittle Leaf Disease; 4.6 Somaclonal Variations, DNA Methylation, and Other Markers; 4.7 Complete Genomes, SNPs, and Genomic Libraries; 4.8 Proteomics; 4.9 Road Map for Date Palm Genomics; References; 5 Rattans and Palmyra; 5.1 Introduction; 5.2 Molecular Markers for Rattans , 5.2.1 Molecular Phylogeny5.2.2 Molecular Markers for Diversity in Rattans; 5.2.3 Marker-Sex Association in Rattans; 5.3 Molecular Markers for Diversity and Sex Association in Palmyra; References; 6 Arecanut; 6.1 Diversity of Areca; 6.2 Molecular Phylogeny of Areca; 6.3 Arecanut and Health Hazards; 6.4 Biomarkers for Arecoline-Induced Damage; 6.5 Xenobiosis, Metabolomics, and Pharmacogenomics; 6.6 Areca Damage and Herbal Remedies; 6.7 Road Map for Areca Genomics; References; 7 Peach Palm; 7.1 Introduction; 7.2 Molecular Phylogeny of Bactridinae , 7.3 Biochemical and Molecular Markers in Peach Palm7.4 Polyphenol Oxidase, Carotenoids, and Antioxidants in Bactris; References; 8 Ornamental, Underutilized, and Vulnerable Palms; 8.1 Attalea, Butia, Carpentaria and Ceroxylon; 8.2 Chamaedorea and Euterpe; 8.3 Geonoma, Howea, Johannesteijsma, Livistona, Licuala, Lodoicea and Metroxylon; 8.4 Nypa, Oenocarpus, Pinanga, and Pseudophoenix; 8.5 Conclusions; References; 9 Molecular Phylogeny of Palms; 9.1 Introduction; 9.2 Random Primers and DNA Barcodes [2-5]; 9.3 Markers for Palms from Other Monocot Plants [7-9]; 9.4 Slow Evolution in Palms , 9.5 Sequence Variations Used in Molecular Phylogeny of Plants [13-17]
    Additional Edition: ISBN 0123877369
    Language: English
    Subjects: Agriculture, Forestry, Horticulture, Fishery, Domestic Science , Biology
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    Keywords: Electronic book
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  • 7
    Online Resource
    Online Resource
    New York, NY : Springer
    UID:
    gbv_165296326X
    Format: Online-Ressource (XIV, 283 p. 78 illus., 46 illus. in color, online resource)
    ISBN: 9781461414247
    Series Statement: Springer Series in Computational Neuroscience 9
    Content: Twenty years ago, the field of Computational Neuroscience was relatively new and many computer models were starting to be constructed of different structures and brain regions. This book seeks to answer the questions, what have we learned over the last twenty years using computational techniques? and what are the most significant challenges that remain? The authors were selected to provide wide coverage of the applications of computational techniques to a broad range of questions and model systems in neuroscience. In addition, several chapters consider the historical development of the field of Computational Neuroscience itself, including its associated modeling technology. These contributions recount the historical record, but also consider what developments are necessary to continue to advance computational understanding of brain function. The book also includes an historical account of the establishment of the annual international meeting in Computational Neuroscience (the “CNS” meeting) more than twenty years ago, and includes annotated reproductions of the first twelve years of posters from that meeting. These posters in and of themselves have become famous in the field, hanging in many laboratories around the world and also in the halls of the NIH in Bethesda. Created at the time as allegories for the state of Computational Neuroscience, they now tell their own story of the origins and development of the field
    Note: Introduction: Origins and History of the Annual CNS meetingsA Pictorial History of the Early Days of Computational Neuroscience:  The CNS Meeting Posters -- History of Neural Simulation Software -- Learning from the past:  Approaches for Reproducibility in Computational Neuroscience -- The Emergence of Community Models in Computational Neuroscience: The 40-year History of the Cerebellar Purkinje Cell -- Calcium: the Answer to Life, the Universe, and Everything -- The more we look, the more biological variation we see: How has and should this influence modeling of small networks? -- 20 years of “noise”: Contributions of computational neuroscience to the exploration of the effect of background activity on central neurons -- Still looking for the memories: molecules and synaptic plasticity -- 20 years of the dynamics of memory: The long and winding road linking cellular mechanisms to behavior -- Spatiotemporal coding in the olfactory system -- 20 years of learning about vision: Questions answered, questions unanswered, and questions not yet asked -- Reinforcement learning models then and now: from single cells to modern neuroimaging -- Index.
    Additional Edition: ISBN 9781461414230
    Additional Edition: Druckausg. 20 years of computational neuroscience New York, NY : Springer, 2013 ISBN 9781461414230
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Medizin ; Neurobiologie ; Bioinformatik ; Neurowissenschaften
    URL: Cover
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  • 8
    Online Resource
    Online Resource
    New York, NY : Springer New York
    UID:
    gbv_165904099X
    Format: Online-Ressource (XVII, 584 p. 123 illus., 59 illus. in color, online resource)
    ISBN: 9781493911547
    Series Statement: Advances in Neurobiology 9
    Content: A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators
    Note: Description based upon print version of record , Introduction to the Complexity of Cell Surface and Tissue Matrix GlycoconjugatesIntroduction to Cells Comprising the Nervous System -- Synthesis, Processing, and Function of N-glycans in N-glycoproteins -- Synthesis of O-linked Glycoconjugates in the Nervous System -- Chemistry and Function of Glycosaminoglycans in the Nervous System -- Use of Glycan-targeted Antibodies/Lectins to Study the Expression/Function of Glycosyltransferases in the Nervous System -- From Mass Spectrometry-based Glycosylation Analysis to Glycomics and Glycoproteomic -- Structural Analysis of Oligosaccharides and Glycoconjugates using NMR -- Glycolipid and Glycoprotein Expression During Neural Development -- Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous System -- Role of Myelin-Associated Glycoprotein (Siglec-4a) in the Nervous System -- Role of Galactosylceramide and Sulfatide in Oligodendrocytes and CNS Myelin: Formation of a Glycosynapse -- Glycosignaling - A General Review -- Glycosphingolipids in the Regulation of the Nervous System -- Glycobiology of Ion Transport in the Nervous System -- O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in Neurodegeneration -- N-glycosylation in Regulation of the Nervous System -- Roles of Carbohydrates in the Interaction of Pathogens with Neural Cells -- Glycoconjugate Changes in Aging and Age-related Diseases -- Gangliosides and Glycolipids in Neurodegenerative Disorders -- Glycosidases: Inborn Errors of Glycosphingolipid Catabolism -- Ganglioside Storage Diseases: On the Road to Management -- Dynamic Aspects of Neural Tumor Gangliosides -- Galectins and Neuroinflammation -- Glycoconjugates and Neuroimmunological Diseases.
    Additional Edition: ISBN 9781493911530
    Additional Edition: Druckausg. ISBN 978-149-391-153-0
    Language: English
    Subjects: Biology
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    Keywords: Glykokonjugate ; Nervensystem
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 9
    Book
    Book
    Cambridge, Massachusetts : Harvard University Press
    UID:
    gbv_1610049128
    Format: xvii, 331 Seiten , Illustrationen, Diagramme, Faksimiles, Karte, genealogische Tafeln
    ISBN: 0674729692 , 9780674729698
    Note: Literaturverzeichnis: Seite 301-315 , Granted the law, Alfred Russel Wallace's evolutionary travelsThe consilient Mr. Wallace, transmutation and related themes of the Species notebook -- Wallace and Darwin, parallels, intersections and departures on the evolutionary road -- Two indefatigable naturalists, Wallace and Darwin's watershed papers -- A striking coincidence, The Wallace-Darwin papers of 1858 compared -- True with a vengeance, from delicate arrangement to conspiracy: a guide coda -- The force of admiration.
    Additional Edition: Online-Ausg. Wallace, Darwin, and the origin of species Cambridge, Mass. [u.a.] : Harvard University Press, 2014 ISBN 9780674416468
    Additional Edition: ISBN 0674416465
    Language: English
    Subjects: Biology
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    Keywords: Wallace, Alfred Russel 1823-1913 ; Darwin, Charles 1809-1882 ; Evolutionsbiologie ; Evolutionstheorie ; Natürliche Auslese ; Wallace, Alfred Russel 1823-1913 ; Darwin, Charles 1809-1882 ; Evolutionsbiologie ; Evolutionstheorie ; Natürliche Auslese
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  • 10
    Online Resource
    Online Resource
    Basel : Birkhäuser Verlag
    UID:
    gbv_1647126177
    Format: Online-Ressource (IX, 349 p, digital)
    ISBN: 9783764375676
    Series Statement: Progress in Drug Research 64
    Content: This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function. There is special emphasis on the identification of drug targets. The book includes practical examples from the various 'omic' sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment.
    Content: "Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. It aims to investigate all interacting components simultaneously and requires data from high throughput techniques. These data from the ""omic"" sciences are computed and used to build in silico models of biological systems that ultimately will prove to be an invaluable tool in drug development. This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a special emphasis on the identification of drug targets. It includes practical examples from the various ""omic"" sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment, as well as those in the academic field with an interest in the functional application of the ""omic"" sciences."
    Note: Description based upon print version of record , CONTENTS; Foreword; Systems biology and its impact on anti-infective drug development; Applications of transcriptional profiling in antibiotics discovery anddevelopment; Chemical genetics: An evolving toolbox for target identificationand lead optimization; Proteomic profiling of cellular stresses in Bacillus subtilis revealscellular networks and assists in elucidating antibiotic mechanismsof action; Elucidating the mode-of-action of compounds from metaboliteprofiling studies; A subsystems-based approach to the identification of drug targetsin bacterial pathogens , Metabolic control analysis to identify optimal drug targetsThe protein network as a tool for finding novel drug targets; Toxicogenomics applied to predictive and exploratory toxicologyfor the safety assessment of new chemical entities:a long road with deep potholes; Biological robustness in complex host-pathogen systems; Toward whole cell modeling and simulation: Comprehensivefunctional genomics through the constraint-based approach; Genomics of host-pathogen interactions; Index
    Additional Edition: ISBN 9783764375669
    Additional Edition: Buchausg. u.d.T. Systems biological approaches in infectious diseases Basel : Birkhäuser, 2007 ISBN 3764375663
    Additional Edition: ISBN 9783764375669
    Language: English
    Subjects: Biology , Medicine
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    Keywords: Infektionskrankheit ; Epidemiologie ; Mathematisches Modell ; Antimikrobieller Wirkstoff ; Arzneimittelentwicklung ; Systembiologie ; Infektionskrankheit ; Epidemiologie ; Mathematisches Modell ; Antimikrobieller Wirkstoff ; Arzneimittelentwicklung ; Systembiologie ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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