Kooperativer Bibliotheksverbund

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Umfang: VI, 438 S. : , Ill.

Ausgabe: 1. publ.

ISBN: 978-1-57113-330-4 , 1-57113-330-5

Serie: Studies in German literature, linguistics and culture

Sprache: Englisch

Fachgebiete: Germanistik

Schlagwort(e): 1877-1962 Hesse, Hermann ; Aufsatzsammlung ; Aufsatzsammlung

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017693871&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017693871&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA

URL: Klappentext

URL: Inhaltsverzeichnis

Mehr zum Autor: Cornils, Ingo, 1958-

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Umfang: 1 online resource (viii, 438 pages) : , illustrations (black and white), digital, PDF file(s).

ISBN: 9781571137296

Serie: Studies in German literature, linguistics, and culture

Inhalt: This volume of new essays sheds light on the major works of Hermann Hesse, including 'Siddhartha', 'Der Steppenwolf' and 'Das Glasperlenspiel'. Another six essays explore Hesse's interest in psychoanalysis, music and eastern philosophy, the development of his political views and the influence of his painting on his writing.

Anmerkung: Previously issued in print: 2009.

Weitere Ausg.: Print version : ISBN 9781571135810

Sprache: Englisch

DOI: 10.1017/9781571137296

URL: https://www.cambridge.org/core/product/identifier/9781571137296/type/BOOK

URL: lizenzpflichtig

UID:

Umfang: 335 S.

Sprache: Englisch

Fachgebiete: Germanistik

Schlagwort(e): 1877-1962 Hesse, Hermann ; Aufsatzsammlung

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Umfang: XII, 324 S.

ISBN: 0-8263-0440-0

Sprache: Englisch

Fachgebiete: Germanistik

Mehr zum Autor: Otten, Anna

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Umfang: 1 online resource (148 pages) : , illustrations

ISBN: 3-03842-746-2

Inhalt: The goal of bioprocessing is to optimize process variables, such as product quantity and quality, in a reproducible, scalable, and transferable manner. However, bioprocesses are highly complex. A large number of process parameters and raw material attributes exist, which are highly interactive, and may vary from batch to batch. Those interactions need to be understood, and the source of variance must be identified and controlled. While purely data-driven correlations, such as chemometric models of spectroscopic data, may be employed for the understanding how process parameters are related to process variables, they can hardly be deployed outside of the calibration space. Currently, mechanistic models, models based on mechanistic links and first principles, are in the focus of development. They are perceived to allow transferability and scalability, because mechanistics can be extrapolated. Moreover, the models deliver a large range of hardly-measureable states and physiological parameters. The current Special Issue wants to display current solutions and case studies of development and deployment of hybrid models and multi-parametric control of bioprocesses. It includes: -Models for Bioprocess Monitoring -Model for Bioreactor Design and Scale Up -Hybrid model solutions, combinations of data driven and mechanistic models. -Model to unravel mechanistic physiological regulations -Implementation of hybrid models in the real-time context -Data science driven model for process validation and product life cycle management.

Anmerkung: About the Special Issue Editor -- Preface to "Hybrid Modelling and Multi-Parametric Control of Bioprocesses" -- Karen Schwab, Jennifer Lauber and Friedemann Hesse Fluorometric In Situ Monitoring of an Escherichia coli Cell Factory with Cytosolic Expression of Human Glycosyltransferase GalNAcT2: Prospects and Limitations -- Karen Schwab and Friedemann Hesse Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations -- Maike Kuschel, Flora Siebler and Ralf Takors Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in LargeScale Bioreactors -- Dominik Egger, Ivo Schwedhelm, Jan Hansmann and Cornelia Kasper Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor -- Dominik Egger, Monica Fischer, Andreas Clementi, Volker Ribitsch, Jan Hansmann and Cornelia Kasper Development and Characterization of a Parallelizable Perfusion Bioreactor for 3D Cell Culture -- Dennis Vier, Stefan Wambach, Volker Schnemann and Klaus-Uwe Gollmer Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra fromFed-Batch Fermentation Samples -- Julian Kopp, Christoph Slouka, Sophia Ulonska, Julian Kager, Jens Fricke, Oliver Spadiut and Christoph Herwig Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) -- Rimvydas Simutis and Andreas Lubbert Hybrid Approach to State Estimation for Bioprocess Control -- Thomas Zahel, Lukas Marschall, Sandra Abad, Elena Vasilieva, Daniel Maurer, Eric M. Mueller, Patrick Murphy, Thomas Natschlger, Ccile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1 -- Thomas Zahel, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Sandra Abad, Elena Vasilieva, Daniel Maurer, C´ecile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Integrated Process Modeling-A Process Validation Life Cycle Companion.

Sprache: Englisch

UID:

Umfang: 1 online resource (148 pages) : , illustrations

Inhalt: The goal of bioprocessing is to optimize process variables, such as product quantity and quality, in a reproducible, scalable, and transferable manner. However, bioprocesses are highly complex. A large number of process parameters and raw material attributes exist, which are highly interactive, and may vary from batch to batch. Those interactions need to be understood, and the source of variance must be identified and controlled. While purely data-driven correlations, such as chemometric models of spectroscopic data, may be employed for the understanding how process parameters are related to process variables, they can hardly be deployed outside of the calibration space. Currently, mechanistic models, models based on mechanistic links and first principles, are in the focus of development. They are perceived to allow transferability and scalability, because mechanistics can be extrapolated. Moreover, the models deliver a large range of hardly-measureable states and physiological parameters. The current Special Issue wants to display current solutions and case studies of development and deployment of hybrid models and multi-parametric control of bioprocesses. It includes: -Models for Bioprocess Monitoring -Model for Bioreactor Design and Scale Up -Hybrid model solutions, combinations of data driven and mechanistic models. -Model to unravel mechanistic physiological regulations -Implementation of hybrid models in the real-time context -Data science driven model for process validation and product life cycle management.

Anmerkung: About the Special Issue Editor -- Preface to "Hybrid Modelling and Multi-Parametric Control of Bioprocesses" -- Karen Schwab, Jennifer Lauber and Friedemann Hesse Fluorometric In Situ Monitoring of an Escherichia coli Cell Factory with Cytosolic Expression of Human Glycosyltransferase GalNAcT2: Prospects and Limitations -- Karen Schwab and Friedemann Hesse Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations -- Maike Kuschel, Flora Siebler and Ralf Takors Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in LargeScale Bioreactors -- Dominik Egger, Ivo Schwedhelm, Jan Hansmann and Cornelia Kasper Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor -- Dominik Egger, Monica Fischer, Andreas Clementi, Volker Ribitsch, Jan Hansmann and Cornelia Kasper Development and Characterization of a Parallelizable Perfusion Bioreactor for 3D Cell Culture -- Dennis Vier, Stefan Wambach, Volker Schnemann and Klaus-Uwe Gollmer Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra fromFed-Batch Fermentation Samples -- Julian Kopp, Christoph Slouka, Sophia Ulonska, Julian Kager, Jens Fricke, Oliver Spadiut and Christoph Herwig Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) -- Rimvydas Simutis and Andreas L ¨ubbert Hybrid Approach to State Estimation for Bioprocess Control -- Thomas Zahel, Lukas Marschall, Sandra Abad, Elena Vasilieva, Daniel Maurer, Eric M. Mueller, Patrick Murphy, Thomas Natschlger, Ccile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1 -- Thomas Zahel, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Sandra Abad, Elena Vasilieva, Daniel Maurer, C´ecile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Integrated Process Modeling-A Process Validation Life Cycle Companion.

Weitere Ausg.: ISBN 3-03842-745-4

Sprache: Englisch

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Umfang: 1 Online-Ressource (324 p.)

Serie: Literature online reference edition

Inhalt: The Cambridge Companion to the Modern German Novel provides a broad ranging introduction to the major trends in the development of the German novel during the late nineteenth and early twentieth centuries. Theodor Fonatne, Hermann Hesse, Thomas Mann, Franz Kafka, and Gunther Grass are among the writers examined. This companionable survey, which includes a chronology and guide to further reading, conveys a vivid sense of the vitality and complexity of the modern German novel and of the debates surrounding it. This book will be essential reading for students.

Weitere Ausg.: Erscheint auch als Druck-Ausgabe Cambridge Companion to The Modern German Novel, edited by Graham Bartram. Cambridge : Cambridge University Press, 2004.

Sprache: Englisch

URL: lizenzpflichtig

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Umfang: 1 Online-Ressource (xxiii, 294 pages) , digital, PDF file(s)

ISBN: 9780511999789

Serie: Cambridge companions to literature

Inhalt: The Cambridge Companion to the Modern German Novel, first published in 2004, provides a broad ranging introduction to the major trends in the development of the German novel from the 1890s to the present. Written by an international team of experts, it encompasses both modernist and realist traditions, and also includes a look back to the roots of the modern novel in the Bildungsroman of the late eighteenth and nineteenth centuries. The structure is broadly chronological, but thematically-focused chapters examine topics such as gender anxiety, images of the city, war, and women's writing; within each chapter, key works are selected for close attention. Unique in its combination of breadth of coverage and detailed analysis of individual works, and featuring a chronology and guides to further reading, this Companion will be indispensable to students and teachers

Anmerkung: Title from publisher's bibliographic system (viewed on 09 Nov 2015) , The German novel in the long twentieth century , Contexts of the novel : society, politics and culture in German-speaking Europe, 1870 to the present , The novel in Wilhelmine Germany : from realism to satire , Gender anxiety and the shaping of the self in some modernist writers : Musil, Hesse, Hofmannsthal, Jahnn , Franz Kafka : the radical modernist , Modernism and the Bildungsroman : Thomas Mann's magic mountain , Apocalypse and utopia in the Austrian novel of the 1930s : Hermann Broch and Robert Musil , Images of the city , Women writers in the "golden" twenties , The First World War and its aftermath in the German novel , The German novel during the Third Reich , History, memory, fiction after the Second World War , Aesthetics and resistance : Böll, Grass, Weiss , The kleiner Mann and modern times : from Fallada to Walser , The "critical" novel in the GDR , Identity and authenticity in Swiss and Austrian novels of the postwar era : Max Frisch and Peter Handke , Subjectivity and women's writing of the 1970s and early 1980s , The postmodern German novel

Weitere Ausg.: ISBN 9780521482530

Weitere Ausg.: ISBN 9780521483926

Weitere Ausg.: Print version ISBN 9780521482530

Sprache: Englisch

DOI: 10.1017/CCOL0521482534

URL: Volltext

UID:

Umfang: IX, 453 S. : , zahlr. graph. Darst.

Ausgabe: 2. ed.

ISBN: 978-3-13-106042-6 , 978-1-58890-488-1

Serie: Thieme foundations of organic chemistry series

Originaltitel: Spektroskopische Methoden in der organischen Chemie

Inhalt: This book provides the necessary equipment for the application of spectroscopic methods in organic chemistry, as required as part of chemistry courses in all universities.The following methods are explained and examples given: UV/Vis Spectroscopy, derivative Spectroscopy, chirooptical methods CD and ORD.Aggregated molecules, charge transfer complexes, conjugated oligomers. Infrared (IR) and Raman Spectroscopy, Fourier transform IR spectroscopy, and GC/IRcombination methods. Nuclear Magnetic Resonance Spectroscopy (NMR), 1H-, 13C-, 19F-, 15N- und 31P-NMR, spin decoupling, triple resonance, INDOR difference spectroscopy, 2D- and 3D-NMR, COSY, TOCSY, ROESY and NOESY spectra, NOE, INEPT, and DEPT technique, DEPTQ, HETCOR, HRMAS, INADEQUATE and lanthanide shift reagents, simulation and calculation of spectra, and the combination of separation and NMR methods.The new 2D NMR techniques TOCSY, HMQC and HMBC, more examples and a guide to completely assign all 1H and 13C NMR signals of a given substrate. Mass spectrometry (MS), electron impact and chemical ionization (EI and CI), fast atom bombardment (FAB), electrospray und thermospray ionization (ESI and TSI), MS/MS technique (MSn), field ionization and field desorption (FI and FD), atmospheric pressure chemical ionization (APCI), MALDI TOF technique, GC/MS, LC/MS, and HPLC-UV(DAD)-APCI combination MS/MS technique. Fourier transform ion cyclotron resonance MS (FT-ICR-MS).The layout and manytables help to introduce the reader to spectroscopy. The extensive and thorough approach makes the text the first choice both as a companion for the professional chemists and as a refresher course in practical spectroscopy.

Sprache: Englisch

Fachgebiete: Chemie/Pharmazie

Schlagwort(e): Organische Chemie ; Spektroskopie ; Lehrbuch ; Organische Verbindungen ; Spektroskopie ; Lehrbuch

URL: http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016683693&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA

Mehr zum Autor: Hesse, Manfred, 1935-2011.

Mehr zum Autor: Meier, Herbert, 1939-

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ISBN: 9780241627402

Serie: DK Eyewitness Travel Guide

Inhalt: " Whether you want to wander the cobblestone streets of a medieval village, seek out the coolest districts in Berlin, or check off a bucket list of iconic landmarks, your DK Eyewitness travel guide makes sure you experience all that Germany has to offer. Synonymous with art and culture, Germany is bursting with world-class museums, trendy galleries and creative hubs. But travel away from the towns and cities and you'll discover some of Europe's finest lakes, no fewer than 16 national parks and a coastline ripe for outdoor adventure. Our newly-updated guide brings Germany to life, transporting you there like no other travel guide does with expert-led insights, trusted travel advice, detailed breakdowns of all the must-see sights, photographs on practically every page, and our hand-drawn illustrations which place you inside the country's iconic buildings and neighbourhoods. Inside DK Eyewitness Germany you will find:- A fully-illustrated top experiences guide: our expert pick of Germany's must-sees and hidden gems. -Accessible itineraries to make the most out of each and every day. -Expert advice: honest recommendations for getting around safely, when to visit each sight, what to do before you visit, and how to save time and money. - Colour-coded chapters to every part of Germany, from Berlin to Munich, Saxony to Hesse. - Practical tips: the best places to eat, drink, shop and stay. - Detailed maps and walks to help you navigate the region country easily and confidently. - Covers: Berlin, Brandenburg, Saxony-Anhalt, Saxony, Thuringia, Southern Germany, Munich, Bavaria, Baden-Württemberg, Western Germany, Rhineland-Palatinate and Saarland, Hesse, North Rhineland-Westphalia, Northern Germany, Lower Saxony, Hamburg and Bremen, Schleswig-Holstein, Mecklenburg-Vorpommern Only visiting Berlin or Munich? Try our DK Eyewitness Berlin or DK Eyewitness Munich and the Bavarian Alps. About DK Eyewitness: At DK Eyewitness, we believe in the power of discovery. We make it easy for you to explore your dream destinations. DK Eyewitness travel guides have been helping travellers to make the most of their breaks since 1993. Filled with expert advice, striking photography and detailed illustrations, our highly visual DK Eyewitness guides will get you closer to your next adventure. We publish guides to more than 200 destinations, from pocket-sized city guides to comprehensive country guides. Named Top Guidebook Series at the 2020 Wanderlust Reader Travel Awards, we know that wherever you go next, your DK Eyewitness travel guides are the perfect companion. "

Inhalt: Biographisches: " Experience the world with DK Eyewitness. DK Eyewitness' highly visual guides show you what others only tell you, with easy-to-read maps, tips and tours to inform and enrich your trip. Our travel writers report on what to see, eat, drink and do around the world, while the very best photographs and illustrations bring cities, regions and countries to life. We publish guides to more than 200 destinations around the world, from handy pocket-sized city guides to comprehensive country guides. DK is the world's leading illustrated reference publisher, producing beautifully designed books for adults and children in over 120 countries. "

Sprache: Englisch

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