Umfang:
Online-Ressource (XXIX, 736 S.)
Ausgabe:
Online-Ausg.
ISBN:
9780121820848
Serie:
Methods in enzymology 183
Inhalt:
This volume addresses a variety of areas in which computers are used to manage and manipulate nucleic acid and protein sequence data. The manipulations include searching, aligning, and determining the significance of similarities, as well as the construction of phylogenetic trees that show the evolutionary history of related sequences. Ready-to-use methods for the "at-the-bench" scientist are presented
Anmerkung:
Includes bibliographical references
,
Includes indexes
,
GenBank: Current status and future directions
,
Mutation data matrix and its uses
,
GenBank: Current status and future directions
,
Mutation data matrix and its uses
,
Literaturangaben
,
EMBL Data Library
,
Protein Sequence Database
,
Cooperation between databases and scientific community
,
Rapid and sensitive sequence comparison with FASTP and FASTA
,
Searching through sequence databases
,
Finding protein similarities with nucleotide sequence databases
,
Use of homology domains in sequence similarity detection
,
Profile analysis
,
Finding protein coding regions in genomic sequences
,
Ancient patterns in nucleic acid sequences
,
Searching for patterns in protein and nucleic acid sequences
,
Consensus patterns in DNA
,
Consensus methods for DNA and protein sequence alignment
,
k-tuple frequency analysis: From intron/exon discrimination to T-cell epitope mapping
,
Splice junctions, branch point sites, and exons: Sequence statistics, identification, and applications to genome project
,
Predicting optimal and suboptimal secondary structure for RNA
,
Detecting pseudoknots and other local base-pairing structures in RNA sequences
,
Computer modeling and display of RNA secondary and tertiary structures
,
Sensitivity comparison of protein amino acid sequences
,
Three-way Needleman--Wunsch algorithm
,
Progressive alignment and phylogenetic tree construction of protein sequences
,
Identification of significant sequence patterns in proteins
,
Protein multiple sequence alignment and flexible pattern matching
,
Genomic divergence through gene rearrangement
,
Multiple sequence comparison
,
Simultaneous comparison of several sequences
,
Hierarchical method to align large numbers of biological sequences
,
Significance of protein sequence similarities
,
Fast alignment of DNA and protein sequences
,
Statistical geometry on sequence space
,
Statistical methods for estimating sequence divergence
,
Converting distance to time: Application to human evolution
,
Maximum likelihood methods
,
Maximum parsimony approach to construction of evolutionary trees from aligned homologous sequences
,
Phylogeny determination using dynamically weighted parsimony method
,
Statistical tests of molecular phylogenies
,
Nearest neighbor procedure for relating progressively aligned amino acid sequences
,
Phylogenetic relationships from three-dimensional protein structures
,
EMBL Data Library
,
Protein Sequence Database
,
Cooperation between databases and scientific community
,
Rapid and sensitive sequence comparison with FASTP and FASTA
,
Searching through sequence databases
,
Finding protein similarities with nucleotide sequence databases
,
Use of homology domains in sequence similarity detection
,
Profile analysis
,
Finding protein coding regions in genomic sequences
,
Ancient patterns in nucleic acid sequences
,
Searching for patterns in protein and nucleic acid sequences
,
Consensus patterns in DNA
,
Consensus methods for DNA and protein sequence alignment
,
k-tuple frequency analysis: From intron/exon discrimination to T-cell epitope mapping
,
Splice junctions, branch point sites, and exons: Sequence statistics, identification, and applications to genome project
,
Predicting optimal and suboptimal secondary structure for RNA
,
Detecting pseudoknots and other local base-pairing structures in RNA sequences
,
Computer modeling and display of RNA secondary and tertiary structures
,
Sensitivity comparison of protein amino acid sequences
,
Three-way Needleman--Wunsch algorithm
,
Progressive alignment and phylogenetic tree construction of protein sequences
,
Identification of significant sequence patterns in proteins
,
Protein multiple sequence alignment and flexible pattern matching
,
Genomic divergence through gene rearrangement
,
Multiple sequence comparison
,
Simultaneous comparison of several sequences
,
Hierarchical method to align large numbers of biological sequences
,
Significance of protein sequence similarities
,
Fast alignment of DNA and protein sequences
,
Statistical geometry on sequence space
,
Statistical methods for estimating sequence divergence
,
Converting distance to time: Application to human evolution
,
Maximum likelihood methods
,
Maximum parsimony approach to construction of evolutionary trees from aligned homologous sequences
,
Phylogeny determination using dynamically weighted parsimony method
,
Statistical tests of molecular phylogenies
,
Nearest neighbor procedure for relating progressively aligned amino acid sequences
,
Phylogenetic relationships from three-dimensional protein structures
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe Molecular evolution San Diego, Calif. [u.a.] : Acad. Press, 1990 ISBN 012182084X
Sprache:
Englisch
Fachgebiete:
Biologie
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