Format:
Online-Ressource (1 online resource (xxii, 749 p.))
,
ill., maps
Edition:
1st ed
Edition:
Online-Ausg. 2011 Electronic reproduction; Available via World Wide Web
ISBN:
9780123848901
,
9780123848918
,
0123848903
,
0123848911
Series Statement:
Elsevier insights
Content:
This multidisciplinary book is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field
Content:
This multidisciplinary book is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field
Note:
Includes bibliographical references
,
pt. 1. Methodological/generalist chapters -- pt. 2. Specialized chapters.
,
Introduction: the need for a holistic approach to infectious diseases
,
(1) Molecular epidemiology and species definition of pathogens
,
(2) Virus species/ Marc Van Regenmortel ; (3) Viral evolution/ Hiroshi Haeno and Yoh ; (4) Species concept in bacteria
,
(5) Population structure of pathogenic bacteria
,
(6) Evolution and pathogenesis of fungal organisms
,
(7) Clonal evolution
,
(8) Co/evolution between host and pathogen
,
(9) Elucidating human migration by means of their pathogens
,
(10) Phylogenetic analysis of pathogens
,
(11) Evolutionary effects of infectious diseases on humans
,
(12) General human population genetics, major genomic projects and their relevance for biomedical research
,
(13) Pathogen and vector sequencing projects
,
(14) Proteomics and Host-Pathogen Interactions: a bright future?
,
(15) Evolution of antibiotic resistance
,
(16) Mechanisms of antiviral resistance
,
(17) Evolution of resistance to insecticides in disease vectors
,
(18) Genetics of major insect vectors
,
(19) Modern morphometrics of medically important insects
,
(20) Multilocus sequence typing of pathogens
,
(21) Analysis of pathogen evolution using microarrays
,
(22) The bioinformatics revolution and infectious diseases
,
(23) Genomics of infectious diseases and private industry
,
(24) Pharmacogenetics: The a la carte medicine of tomorrow?
,
(25) Experimental recombination in trypanosomes: its relevance for formal genetics and epidemiology
,
(26) Population genetics of Plasmodium falciparum and the challenge of drug Resistance
,
(27) Molecular evolution of Trypanosoma cruzi: a new paradigmal model of basic science?
,
(28) Identification of Mycobacterium tuberculosis populations using microarrays: does it permit routine molecular epidemiology?
,
(29) The evolution and dynamics of methicillin/resistant Staphylococus aureus: can it be controlled by public health measures?/ Gerrit Kuhn & Dominique Blanc ; (30) The origins of human immunodeficiency virus and implications for global Epidemics
,
(31) Evolution of SARS coronavirus and the relevance of modern molecular Epidemiology
,
(32) Ecology and evolution of avian influenza: the risk of a major pandemics/ Ron. A.M. Fouchier.
,
Electronic reproduction; Available via World Wide Web
Additional Edition:
ISBN 9780123848901
Additional Edition:
Erscheint auch als Druck-Ausgabe Genetics and evolution of infectious disease
Language:
English
Keywords:
Electronic book
URL:
Volltext
(An electronic book accessible through the World Wide Web; click for information)
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