Umfang:
Online Ressource (1 v.)
,
illustrations (some color)
Ausgabe:
Online-Ausg.
ISBN:
0124160174
,
9786613354952
,
6613354953
,
9780124160170
,
1283354950
,
0123914493
,
9781283354950
,
9780123914491
Serie:
Elsevier insights
Inhalt:
1: Solid Phase Microextraction in Perspective -- 2: Theory of Solid Phase Microextraction -- 3: Development of SPME Devices and Coatings -- 4: SPME Commercial Devices and Fiber Coatings -- 5: Automated SPME Systems -- 6: Calibration -- 7: Solid Phase Microextraction Method Development -- 8: SPME and Environmental Analysis -- 9: Application of Solid Phase Microextraction in Food and Fragrance Analysis -- 10: Drug Analysis by SPME -- 11: Ligand-Receptor Binding and Determination of Free Concentrations -- 12: In Vivo Sampling with Solid Phase Microextraction -- 13: Solid Phase Microextraction Protocols
Inhalt:
The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed. This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method. Practical application of Solid Phase Microextraction methods including detailed steps Provides history of extraction methods to better understand the process Suitable for all levels, from beginning student to experienced practitioner
Anmerkung:
Includes bibliographical references. - Online resource and print version record (viewed December 16, 2015)
,
Front Cover; Handbook of Solid Phase Microextraction; Copyright Page; Contents; Preface; List of Contributors; 1 Solid-Phase Microextraction in Perspective; 1.1 Sample Preparation as Part of the Analytical Process; 1.2 Classification of Extraction Techniques; 1.3 Perspective on Microextraction Techniques; 1.4 Implementations of SPME; 1.5 Miniaturisation and Integration; 1.6 In Vivo Analysis; 1.7 SPME Versus SPE; References; 2 Theory of Solid-Phase Microextraction; 2.1 Introduction; 2.2 SPME Principle; 2.3 Thermodynamics; 2.3.1 Distribution Constant; 2.3.2 Estimation of Distribution Constants
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2.3.3 Effect of Extraction Parameters on Distribution Constants2.3.3.1 Temperature; 2.3.3.2 Salting; 2.3.3.3 pH; 2.3.3.4 Polarity of Sample Matrix and Coating Material; 2.3.4 Distribution Constants in the Heating-Cooling Environment; 2.3.5 Multiphase Equilibria in SPME; 2.3.6 Matrix Effects; 2.3.7 Characteristics of the Extraction Phases; 2.4 Kinetics; 2.4.1 Direct Extraction; 2.4.1.1 Perfect Agitation; 2.4.1.2 Practical Agitation; 2.4.2 Desorption of Extracted Analytes; 2.4.3 Headspace Extraction; 2.4.4 Indirect SPME Extraction Through a Membrane; 2.5 Extraction with Derivatisation
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2.6 Extraction of Sample Matrices Containing Solids2.6.1 Convolution Model of Extraction; 2.7 Solid Versus Liquid Sorbents; 2.8 Passive TWA Sampling; 2.9 In-Tube SPME; 2.10 Experimental Verification; References; 3 Development of SPME Devices and Coatings; 3.1 Historical Perspective; 3.2 Rational Design of SPME Devices; 3.2.1 Agitation for Air Sampling; 3.2.2 Agitation for Aqueous Sampling; 3.2.3 Cold-Fibre SPME; 3.2.4 High-Surface-Area Samplers (Thin-Film Microextraction); 3.3 On-Site Samplers; 3.3.1 Field Samplers; 3.3.2 NT Devices; 3.3.3 TWA Devices; 3.3.4 In Vivo Samplers
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3.4 Development of New SPME Coatings3.4.1 Coating Preparation Methods; 3.4.1.1 Dipping Technique; 3.4.1.2 Electrodeposition; 3.4.1.3 Hollow Fibre Membranes/Adhesive Tape; 3.4.1.4 Adhesion of Coatings; 3.4.1.5 Conducting Polymers; 3.4.1.6 Sol-Gel Coatings; 3.4.2 Affinity-Based Coatings; 3.4.2.1 Molecularly Imprinted Polymer Coatings; 3.4.2.2 Immunoaffinity Coatings; 3.4.3 Biocompatible Coatings; 3.4.3.1 Biocompatible Polymer Coatings; 3.4.3.2 Restricted Access Materials; 3.5 Interfaces to Analytical Instrumentation; 3.5.1 SPME-GC Interface; 3.5.2 Field Portable SPME-Fast GC
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3.5.3 SPME-HPLC Interface3.5.4 SPME-MALDI Interface; 3.5.5 SPME-Nanospray MS Interface; 3.5.6 Other Interfaces; References; 4 SPME Commercial Devices and Fibre Coatings; 4.1 Introduction; 4.2 Description of SPME Fibre Assemblies and Holders; 4.2.1 Assemblies with 24- Versus 23-Gauge Needles; 4.2.2 GC Inlet Seals; 4.3 Description of Fibre Cores, Coatings and the Coating Process; 4.3.1 Types and Selection of Fibre Cores; 4.3.1.1 Fused Silica Core; 4.3.1.2 Stableflex Fibre Core; 4.3.1.3 Metal Fibre Core; 4.3.2 Types of Commercially Available SPME Coatings; 4.3.2.1 Determination of Phase Volume
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4.3.2.2 Fibre Coating Temperature and pH Ranges
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1: Solid Phase Microextraction in Perspective -- 2: Theory of Solid Phase Microextraction -- 3: Development of SPME Devices and Coatings -- 4: SPME Commercial Devices and Fiber Coatings -- 5: Automated SPME Systems -- 6: Calibration -- 7: Solid Phase Microextraction Method Development -- 8: SPME and Environmental Analysis -- 9: Application of Solid Phase Microextraction in Food and Fragrance Analysis -- 10: Drug Analysis by SPME -- 11: Ligand-Receptor Binding and Determination of Free Concentrations -- 12: In Vivo Sampling with Solid Phase Microextraction -- 13: Solid Phase Microextraction Protocols.
Weitere Ausg.:
ISBN 1283354950
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe Pawliszyn, Janusz Handbook of solid phase microextraction Chennai ; Oxford : Elsevier, 2011
Sprache:
Englisch
Schlagwort(e):
Fest-Flüssig-Extraktion
;
Electronic books
URL:
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