UID:
almafu_9958130327002883
Format:
1 online resource (593 p.)
ISBN:
1-299-36553-1
,
0-323-14500-0
Content:
Asymmetric Synthesis V3
Note:
Description based upon print version of record.
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Front Cover; Stereodifferentiating Addition Reactions Part B; Copyright Page; Dedication; Table of Contents; Contributors; Preface; Chapter 1. Stereoselective Alkylation Reactions of Chiral Metal Enolates; I. Prologue; II. Selective Enolate Formation; III. Enolate Structure; IV. Transition-State Control Elements; V. Intraannular Chirality Transfer; VI. Chelate-Enforced Intraannular Chirality Transfer; VII. Extraannular Chirality Transfer; VIII. Conclusions; Acknowledgments; References; Chapter 2. The Aldol Addition Reaction; I. Simple Diastereoselection; II. Diastereofacial Selectivity
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ReferencesChapter 3. Asymmetric Synthesis via Chiral Oxazolines; I. Introduction; II. (R)- and (S)-Dialkylacetic Acids; III. (R)- or (S)-2-Substituted Butyrolactones and Valerolactones; IV. Optically Active β-Hydroxy and β -Methoxy Acids; V. β-Hydroxy Esters via Aldol Condensation; VI. Optically Active 2-Methoxyalkanoic and 2-Chloroalkanoic Acids; VII. Thiiranes; VIII. Asymmetric Reductions; IX. Chiral Grignard Reagents; X. Kinetic Resolution of Racemic Alkyl Halides; XI. Optically Active 2-Hydroxycarboxylic Acids; XII. Chiral Phthalides; XIII. (R)- and (S)-β,β-Dialkylpropionic Acids
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XIV. (R)- and (S)-β-Substituted ValerolactonesXV. α,β,β-Trisubstituted Propionic Acids; XVI. (S)-4-Substituted 1,4-Dihydropyridines; XVII. Chiral Binapthyls; References; Chapter 4. Alkylation of Chiral Hydrazones; I. Introduction; II. The SAMP-/RAMP-Hydrazone Method; III. Asymmetric Carbon-Carbon Bond Formations α to the Carbonyl Group via SAMP-/RAMP-Hydrazones; IV. Mechanistic Studies; V. Applications of the SAMP-/RAMP-Hydrazone Method to Asymmetric Syntheses of Natural Products; VI. Conclusion and Outlook; Acknowledgments; References; Note Added in Proof
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Chapter 5. Olefin Cyclization Processes That Form Carbon-Carbon BondsI. Introduction; II. Ring Fusion: Relationship between Chiral Centers A and B; III. Orientation of Adjacent Rings: Relationship between Chiral Centers A and C; IV. Effect of a Substituent on Ring 1 on the Chirality of Cyclization: Influence of Chiral Center D; V. Effect of a Substituent on Ring 2 on the Chirality of Cyclization: Influence of Chiral Center E; VI. Stereochemistry of Termination: Relationship between Chiral Center F and the Others; VII. Chiral Auxiliaries
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VIII. Mechanistic Conclusions: Are the Cyclizations Concerted or StepwiseAcknowledgment; References; Chapter 6. Olefin Cyclization Processes That Form Carbon-Heteroatom Bonds; I. Introduction; II. Formation of Oxygen Heterocycles; III. Formation of Nitrogen Heterocycles; IV. Formation of Sulfur Heterocycles; Acknowledgment; References; Chapter 7. Asymmetric Cycloaddition Reactions; I. Introduction; II. Intermolecular Diels-Alder Reactions; III. Intramolecular Diels-Alder Processes; IV. [2 + 2] Cycloadditions; V. [3 + 2] Cycloadditions; References
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Chapter 8. Chirality Transfer via Sigmatropic Rearrangements
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English
Additional Edition:
ISBN 0-12-507703-3
Language:
English
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