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Umfang: 1 online resource (343 p.)

ISBN: 9780128009130 , 0128009136

Inhalt: Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures; Offers in-depth anatomy and morphological views of organ systems; Written descriptions convey developmental origins of the organ systems.

Anmerkung: Description based upon print version of record. , Front Cover -- Kaufman's Atlas of Mouse Development Supplement -- Copyright Page -- Dedication -- Contents -- List of Contributors -- 1 Introduction -- 2 Coronal Sections -- Introduction -- Methods -- Results -- Discussion -- Acknowledgments -- References -- 3 A Revised Staging of Mouse Development Before Organogenesis -- Introduction -- Methods -- Overview of the Revised Staging System, TS1-12 -- Anatomy of Stages with Representative Molecular Markers -- Preimplantation Stages: TS1-5, E0 to E3.5 (Figure 3.1) -- From Implantation to the Prestreak Stage: TS6-9a, E4.5-6.5 (Figure 3.2) -- Early Primitive Streak to Late Pre-Headfold. TS9b-11b, E 6.5-E7.5 (Figure 3.3) -- Early Headfold to Early Somitogenesis. TS11a-12, E7.5-8 (Figure 3.4) -- Timing and Litter Variation -- Discussion -- Acknowledgments -- References -- 4 Development of Early Embryonic Lineages -- Introduction -- Preimplantation Development -- Formation of outer and inner cells of the blastocyst (TS3-4 E2.5-3) -- Formation of the primitive endoderm (TS4-5 E3-3.5) -- Postimplantation Development -- Implantation (TS6 E4.5) -- Specification of the embryonic anteroposterior axis (by TS7d E5.75) -- Initiation of gastrulation (TS9a-b E6.25-6.5) -- Formation of definitive endoderm (TS9b-10b E6.5-7.0) -- Formation of the primitive central nervous system (TS9a E6.5 onwards) -- Formation of mesoderm (TS9b E6.5 onward) -- Amnion formation (TS9b-11a E6.5-7.5) -- Function of the node (TS9b-TS12 E6.5-8.0) -- The notochord: Axial mesendoderm (TS10a-TS12 E7.0-8.0) -- Left/right patterning (TS11d-TS12 E7.5-8.0) -- Initiation of somitogenesis and the restriction of potency in the epiblast (TS11d E8.0 onwards) -- Discussion and prospects -- Acknowledgment -- References -- 5 The Alimentary Canal -- Introduction -- Current Views and Molecular Mechanisms of Developing Gut Anatomy. , Morphogenesis and patterning of the gut tube -- Foregut morphogenesis and patterning -- Midgut morphogenesis and patterning -- Hindgut morphogenesis and patterning -- Additional aspects of alimentary canal patterning -- Concluding Remarks -- References -- 6 The Pancreas -- Introduction -- The Current View of the Developmental Anatomy of the Pancreas -- Formation of the pancreatic anlagen (E8.5-10.5) -- Morphogenesis and fusion of the pancreatic anlagen (E10.5-17.5) -- Morphogenesis of the spleen -- The adult pancreas -- Discussion -- References -- 7 Development of the Heart and Great Vessels -- Addition of Cardiac Populations to the Early Heart Tube -- Atrial Septation -- Formation and Incorporation of the Pulmonary Vein -- Septation and Separation of the OFT -- Discussion -- References -- 8 Ontogeny of the Hematopoietic System -- Introduction -- Sites of Hematopoietic Progenitor Generation -- The yolk sac: Two waves of hematopoietic progenitors generation -- The para-aortic splanchnopleura/aorta-gonads-mesonephros: hematopoietic stem cells generation -- Midgestation Hematopoietic Sites -- Fetal liver -- Fetal thymus -- Late Gestation-Perinatal Hematopoietic Sites -- Spleen -- Bone marrow -- Conclusion -- Abbreviations -- References -- 9 The Reproductive System -- Introduction -- The Early Stages -- Formation of the intermediate mesoderm -- Primordial germ cells (PGCs) -- The Indifferent or Bipotential Stage -- Female Development -- Male Development -- Discussion -- Acknowledgments -- References -- 10 Development of the Respiratory System -- Overview -- Foregut morphogenesis, and establishment of trachea and primary lung buds -- Structure of the trachea -- Branching morphogenesis of the primary lung buds up to about E14.5 -- Branching, morphogenesis, and differentiation of the endoderm after E14.5. , Development of the pulmonary blood supply, alveologenesis and the early postnatal growth, and remodeling and maturation of ... -- Lineage tracing of lung mesoderm -- Differentiation and function of lung mesothelium -- Discussion -- References -- 11 The Urinary System -- Introduction -- The Current View of the Developmental Anatomy of the System -- New Lineage Data -- Discussion -- Further Resources -- References -- 12 Integument and Associated Integumentary Appendages -- Introduction: The Structural Diversity of the Mouse Integument -- Early Integumental Development -- Specification of discrete domains in the ectoderm -- Origin, migration, and formation of the dermis -- Cornea, Interfollicular Skin, and Pilosebaceous Units -- Cornea -- Interfollicular skin -- Different types of hairs, their patterns, and time schedules -- Molecular mechanisms involved in the formation of hair placodes and subsequent cellular proliferation -- Hair follicle morphogenesis and segregation of two types of stem cells in the developing pilosebaceous unit -- Development of the sebaceous gland and related glandular structures -- The Mammary Gland -- Formation of the mammary line and associated mesenchyme -- Formation of the specific types of mammary placodes -- Formation of the embryonic mammary gland -- Other Ducted Cutaneous Glands -- Eccrine sweat glands -- Salivary glands -- Lacrimal and Harderian glands -- Discussion -- References -- 13 The Axial Musculoskeletal System -- Introduction -- The Current View of the Developmental Anatomy of the System -- Developmental anatomy of the segmentation process -- Somite differentiation -- The sclerotome -- The dermomyotome and the myotome -- The syndetome -- New Lineage Data -- Sclerotome -- Dermomyotome and myotome -- Discussion -- References -- 14 Spinal Cord and Peripheral Nervous System -- Introduction. , The Current View of the Developmental Anatomy of the Spinal Cord and the Peripheral Nervous System -- Neurulation and neural tube defects -- Anteroposterior patterning and segmental organization of the spinal cord -- Segmental organization of the peripheral nervous system -- Segmental neural crest cell migration -- Segmental organization of somatic and sympathetic efferent nerves -- Development of the parasympathetic nervous system: a special case -- The enteric nervous system -- Dorsoventral patterning of the neural tube -- The development of neuronal pathways within the spinal cord -- General principles -- The formation of sensory-motor connections -- The formation of motor columns -- Formation of spinal nerves -- The refinement of connections -- Discussion -- Acknowledgments -- References -- 15 Limb Development -- Introduction -- AnatomicAL Features of the Early Limb Bud -- Limb Initiation and Specification -- Limb Outgrowth -- Proximodistal axis -- Anteroposterior axis -- Integrating proximodistal and anteroposterior signaling -- Dorsoventral axis -- Programmed cell death -- Chondrogenesis and joint formation -- Tendon and ligament development -- Muscle formation -- Conclusion -- References -- 16 The Craniofacial Region -- Introduction -- The Current View of the Developmental Anatomy of the Head and Neck -- Early morphogenesis of the cranial region and formation of the pituitary and pineal glands -- Origin of the craniofacial tissue components -- The embryonic face and pharynx -- Early development -- Pharyngeal arches, pouches, and clefts -- Cranial nerves -- Melanocytes -- The skull -- The skull base -- The skull vault and face -- Discussion -- Acknowledgments -- References -- 17 Recent Advances in Palate and Tongue Development -- Introduction -- The Current View of the Developmental Anatomy of the Palate and Tongue -- Palate development. , Patterning of the palatal shelves -- Elevation of the palatal shelves -- Palatal shelf growth: proliferation of the CNCC-derived mesenchyme -- Palatal fusion -- Soft palate development -- Tongue development -- Myogenic lineage in the developing tongue -- Cranial neural crest-derived mesenchyme in the developing tongue -- Myogenic stem cells, tongue disease, and therapeutic perspectives -- Discussion -- References -- 18 The Developmental Anatomy of Teeth -- Introduction -- The Current View of the Developmental Anatomy of Teeth -- The dental lamina -- Tooth placodes -- Enamel knots -- Stem cells in the continuously growing mouse incisor -- New lineage data -- Discussion -- Acknowledgments -- References -- 19 Brain Development -- Introduction -- The Current View of the Developmental Anatomy of the Mouse Brain -- Neural Induction, neurulation, and early regionalization -- The Developmental Anatomy of the Mouse Cerebral Neocortex -- The origin and migration of cortical neurons -- Pyramidal cells and radial migration -- Interneuron generation and tangential migration -- Cell death during early cortical development -- Mechanisms Controlling Development of the Mouse Cerebral Neocortex -- Extrinsic and intrinsic influences on cortical development -- Thalamic and thalamocortical development -- Formation of maps in the cortex -- Connectivity between regions -- Mouse barrel formation: an example of map formation -- Plasticity during development -- Development of the Mouse Cerebellum -- Cerebellar specification -- Genesis of the cerebellum -- The Formation of cerebellar connections -- Conclusions -- Acknowledgments -- References -- 20 The Visual System -- Introduction -- The Current View of the Developmental Anatomy of the Visual System -- Establishing the Eye Field -- Signals -- Transcription Factors -- Separating the Eye Field. , Optic Vesicle Patterning and Morphogenesis.

Weitere Ausg.: ISBN 9780128000434

Weitere Ausg.: ISBN 0128000430

Sprache: Englisch