Kooperativer Bibliotheksverbund

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Umfang: 1 online resource (253 p.)

Ausgabe: 1st ed.

ISBN: 9780128010785 , 0128010789 , 9780128013250 , 0128013257

Anmerkung: Description based upon print version of record. , ""Cover""; ""Title Page""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Overview""; ""Chapter 1 - Sepsis""; ""Introduction""; ""The microcirculation in sepsis""; ""The endothelium""; ""Nitric oxide and sepsis""; ""Arterioles""; ""Capillaries""; ""Venules""; ""Permeability""; ""Blood cells""; ""The Inflammatory Response in Sepsis""; ""Platelets in sepsis""; ""Thrombosis and coagulation in sepsis""; ""Models""; ""Genetics and sepsis""; ""Treatments for sepsis""; ""Conclusions""; ""Acknowledgment""; ""References""; ""Chapter 2 - Neutrophil-Mediated Vascular Host Defense"" , ""Introduction""""Bloodstream infections""; ""Conventional vascular host defense""; ""Neutrophil extracellular trap mediated vascular immunity""; ""Immunothrombosis""; ""NET-mediated tissue damage""; ""Conclusions""; ""References""; ""Chapter 3 - Platelets as Mediators of the Vascular Response to Infection""; ""Introduction""; ""Platelet and hemostasis""; ""Platelets and the response to infection""; ""Platelet-bacteria interactions""; ""Direct binding""; ""Indirect binding""; ""Shear stress""; ""Secreted products""; ""Platelet activation""; ""Platelets and sepsis""; ""Conclusions"" , ""References""""Chapter 4 - Mechanisms of Bacterial Interaction with Cells of the Blood-Cerebrospinal Fluid Barrier""; ""Introduction""; ""Bacterial meningitis""; ""Neuropathology and Clinical Presentation of Bacterial Meningitis""; ""N. meningitidis""; ""GBS""; ""Blood-brain barrier/blood-cerebrospinal fluid barrier""; ""In Vivo and In Vitro Models to Study the Pathogenesis of Bacterial Meningitis""; ""Bacterial ligand-receptor interactions""; ""Meningococcal Type IV Pili""; ""Meningococcal Opa and Opc Proteins""; ""Other Meningococcal Adhesins and Cortical Plaque Formation"" , ""GBS Surface Adhesins and Invasins""""GBS Pili and Other ECM-Binding Proteins""; ""Signal-transduction mechanisms""; ""Analysis of the host cell transcriptome in response to bacterial infection""; ""Meningococcal Infection""; ""GBS Infection""; ""Meningococcal Manipulation of the Outer Cell Membrane Lipid Composition""; ""Summary""; ""Acknowledgments""; ""References""; ""Chapter 5 - Vascular Responses to Chlamydia pneumoniae Infection""; ""Introduction""; ""Direct interaction with vascular cells""; ""Receptor-Mediated Binding and Uptake"" , ""C. pneumoniae Uses the Mannose 6-Phosphate Receptor on Endothelial Cells""""C. pneumoniae Binds to and Activates the LOX-1 Receptor on Endothelial Cells""; ""The C. pneumoniae Developmental Cycle and Persistent Infection""; ""Effects on Host Cell Energy Metabolism""; ""Inflammatory Activation of Vascular Cells and the Role of Toll-Like Receptors""; ""Foam Cell Formation""; ""Effects on Host Cell Turnover""; ""Systemic responses to infection and the impact on the vasculature""; ""Evidence of the Association of C. pneumoniae Infection and Atherosclerosis in Humans""; ""Clinical Trials"" , ""Animal Models of C. pneumoniae Infection: Effects on Atherosclerosis and Vascular Compliance"" , English

Sprache: Englisch

Schlagwort(e): Electronic books.

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